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The catalytic domains of two closely related cysteine proteinases (CP l and CP2) from Trypanosoma congolense, referred to as Cl and C2, were expressed as proforms in Escherichia coli (C 1) and in the baculovirus system (C I and C2). While the bacterial expression system did not allow recovery of ...


Boulange, A.F.Serveau, C.Brillard, M.Minet, C.Gauthier, F.Diallo, A.Lalmanach, G.Authié, E.[Functional expression of the catalytic domains of two cysteine proteinases from Trypanosoma congolense]Functional expression of the catalytic domains of two cysteine proteinases from Trypanosoma congolense

Congopain and cruzipain, the major cysteine proteinases from Trypanosoma congolense and Trypanosoma cruzi, were compared for their activities towards a series of new, sensitive fluorogenic substrates of the papain family of cysteine proteinases and for their sensitivity to inhibition by cystatins...


Chagas, J.R.Authié, E.Servean, C.Lalmanach, G.Juliano, L.Gauthier, F.[A comparison of the enzymatic properties of the major cysteine proteinases from Trypanosoma congolense and Trypanosoma cruzi]A comparison of the enzymatic properties of the major cysteine proteinases from Trypanosoma congolense and Trypanosoma cruzi

Memory T- and B-cell responses to trypanosome antigens were measured in peripheral blood mononuclear cells, spleen and lymph node cells obtained from 4 trypanotolerant N'Dama cattle which had been exposed to 6 experimental infections with Trypanosoma congolense. These cattle were treated with try...


Lutje, V.Taylor, K.A.Boulange, A.F.Authié, E.[Trypanosoma congolense: Tissue distribution of long-term T- and B-cell responses in cattle]Trypanosoma congolense: Tissue distribution of long-term T- and B-cell responses in cattle
Authié, E.Duvallet, G.Robertson, C.Williams, D.J.L.[Antibody response to a 33 kDa cysteine protease of Trypanosoma congolense: Relationship to 'trypanotolerance' in cattle]Antibody response to a 33 kDa cysteine protease of Trypanosoma congolense: Relationship to 'trypanotolerance' in cattle
Williams, D.J.L.Logan-Henfrey, L.L.Authié, E.Seely, C.McOdimba, F.A.[Experimental infection with a haemorrhage-causing Trypanosoma vivax in N'Dama and Boran cattle]Experimental infection with a haemorrhage-causing Trypanosoma vivax in N'Dama and Boran cattle

Trypanosomosis is one of the major constraints on animal production in areas of Africa which have the greatest potential for significant increases in domestic livestock populations and livestock productivity. While the eradication of trypanosomosis from the entire continent is an unrealistic goal...


D'Ieteren, G.D.M.Authié, E.Wissocq, N.M.Murray, M.[Trypanotolerance, an option for sustainable livestock production in areas at risk from trypanosomiasis]Trypanotolerance, an option for sustainable livestock production in areas at risk from trypanosomiasis
Maille, J.C.Authié, E.D'Ieteren, G.D.M.Leak, S.G.A.Maehl, J.H.H.Nagda, S.M.Rarieya, J.M.Rowlands, G.J.Sauveroche, B.Thorpe, W.R.Trail, J.C.M.Yangari, G.[Aspects of trypanotolerance and associations with growth rate in post-weaner N'Dama cattle under high trypanosomiasis risk]Aspects of trypanotolerance and associations with growth rate in post-weaner N'Dama cattle under high trypanosomiasis risk
Akol, G.W.O.Authié, E.Pinder, M.Moloo, S.K.Roelants, G.E.Murray, M.[Susceptibility and immune responses of Zebu and Taurine cattle of West Africa to infection with Trypanosoma congolense transmitted by Glossina morsitans centralis]Susceptibility and immune responses of Zebu and Taurine cattle of West Africa to infection with Trypanosoma congolense transmitted by Glossina morsitans centralis

Approximately 320 East African Zebu cows over 36 months of age were monitored monthly from 1986 to 1992 in nine village herds in an area of high trypanosomiasis risk in southwest Ethiopia where there was resistance to all available trypanocidal drugs. Cows were individually treated with diminazen...


Rowlands, G.J.Mulatu, W.Authié, E.D'Ieteren, G.D.M.Leak, S.G.A.Nagda, S.M.[Effects of trypanosomiasis on reproduction of East African Zebu cows exposed to drug-resistant trypanosomes]Effects of trypanosomiasis on reproduction of East African Zebu cows exposed to drug-resistant trypanosomes

Trypanosomiasis is a serious constraint to livestock production in sub-Saharan Africa. Some breeds of cattle are genetically more resistant to the pathogenic effects of trypanosome infection. We measured B-cell activation and the quantity and isotype of antibody produced at the cellular level in ...


Taylor, K.A.Lutje, V.Kennedy, D.Authié, E.Boulange, A.F.Logan-Henfrey, L.L.Gichuki, B.Gettinby, G.[Trypanosoma congolense: B-Lymphocyte responses differ between trypanotolerant and trypanosusceptible cattle]Trypanosoma congolense: B-Lymphocyte responses differ between trypanotolerant and trypanosusceptible cattle

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