Trypanosomes are covered with a dense layer of antigenically identical glycoproteins. These molecules are highly immunogenic and elicit an antibody response in the infected host. Antibodies against the surface-exposed epitopes of the trypanosome variable surface glycoproteins (VSG) mediate the de...
Williams, D.J.L.
,
Taylor, K.
,
Wilkie, B.
,
Gichuki, B.
,
Authié, E.
,
[Antibody responses to the surface-exposed epitopes of the trypanosome variable surface glycoprotein in N'Dama and Boran cattle]
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Antibody responses to the surface-exposed epitopes of the trypanosome variable surface glycoprotein in N'Dama and Boran cattle
Authié, E.
,
Muteti, D.K.
,
Williams, D.J.L.
,
[Antibody responses to invariant antigens of Trypanosoma congolense in cattle of differing susceptibility to trypanosomiasis]
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Antibody responses to invariant antigens of Trypanosoma congolense in cattle of differing susceptibility to trypanosomiasis
Boulange, A.F.
,
Authié, E.
,
[A 69-KDa immunodominant antigen of Trypanosoma (Nannomonas) congolense is homologous to immunoglobulin heavy chain binding protein (Bip)]
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A 69-KDa immunodominant antigen of Trypanosoma (Nannomonas) congolense is homologous to immunoglobulin heavy chain binding protein (Bip)
Memory T- and B-cell responses to trypanosome antigens were measured in peripheral blood mononuclear cells, spleen and lymph node cells obtained from 4 trypanotolerant N'Dama cattle which had been exposed to 6 experimental infections with Trypanosoma congolense. These cattle were treated with try...
Lutje, V.
,
Taylor, K.A.
,
Boulange, A.F.
,
Authié, E.
,
[Trypanosoma congolense: Tissue distribution of long-term T- and B-cell responses in cattle]
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Trypanosoma congolense: Tissue distribution of long-term T- and B-cell responses in cattle
Authié, E.
,
Duvallet, G.
,
Robertson, C.
,
Williams, D.J.L.
,
[Antibody response to a 33 kDa cysteine protease of Trypanosoma congolense: Relationship to 'trypanotolerance' in cattle]
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Antibody response to a 33 kDa cysteine protease of Trypanosoma congolense: Relationship to 'trypanotolerance' in cattle
Williams, D.J.L.
,
Logan-Henfrey, L.L.
,
Authié, E.
,
Seely, C.
,
McOdimba, F.A.
,
[Experimental infection with a haemorrhage-causing Trypanosoma vivax in N'Dama and Boran cattle]
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Experimental infection with a haemorrhage-causing Trypanosoma vivax in N'Dama and Boran cattle
Akol, G.W.O.
,
Authié, E.
,
Pinder, M.
,
Moloo, S.K.
,
Roelants, G.E.
,
Murray, M.
,
[Susceptibility and immune responses of Zebu and Taurine cattle of West Africa to infection with Trypanosoma congolense transmitted by Glossina morsitans centralis]
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Susceptibility and immune responses of Zebu and Taurine cattle of West Africa to infection with Trypanosoma congolense transmitted by Glossina morsitans centralis
T-cell-mediated immune responses to defined antigens of Trypanosoma congolense were measured in cattle undergoing primary infection. The antigens used were the variable surface glycoprotein and two invariant antigens, a 33-kDa cysteine protease (congopain) and a recombinant form of a 69-kDa heat-...
Lutje, V.
,
Mertens, B.
,
Boulange, A.F.
,
Williams, D.J.L.
,
Authié, E.
,
[Trypanosoma congolense: Proliferative responses and interleukin production in lymph node cells of infected cattle]
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Trypanosoma congolense: Proliferative responses and interleukin production in lymph node cells of infected cattle
African animal trypanosomosis (nagana) is arguably the most important parasitic disease affecting livestock in sub-Saharan Africa. Since none of the existing control measures are entirely satisfactory, vaccine development is being actively pursued. However, due to antigenic variation, the quest f...
Boulange, A.F.
,
Khamadi, S.A.
,
Pillay, D.
,
Coetzer, T.H.T.
,
Authié, E.
,
[Production of congopain, the major cysteine protease of Trypanosoma (Nannomonas) congolense, in Pichia pastoris reveals unexpected dimerization at physiological Ph]
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Production of congopain, the major cysteine protease of Trypanosoma (Nannomonas) congolense, in Pichia pastoris reveals unexpected dimerization at physiological Ph
Rowlands, G.J.
,
Authié, E.
,
D'Ieteren, G.D.M.
,
Leak, S.G.A.
,
Mulatu, W.
,
Nagda, S.M.
,
Peregrine, A.S.
,
[An epidemiological study of recurrent trypanosome infection in East African Zebu cattle and its association with drug resistance]
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An epidemiological study of recurrent trypanosome infection in East African Zebu cattle and its association with drug resistance