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Trypanosomes are covered with a dense layer of antigenically identical glycoproteins. These molecules are highly immunogenic and elicit an antibody response in the infected host. Antibodies against the surface-exposed epitopes of the trypanosome variable surface glycoproteins (VSG) mediate the de...


Williams, D.J.L.Taylor, K.Wilkie, B.Gichuki, B.Authié, E.[Antibody responses to the surface-exposed epitopes of the trypanosome variable surface glycoprotein in N'Dama and Boran cattle]Antibody responses to the surface-exposed epitopes of the trypanosome variable surface glycoprotein in N'Dama and Boran cattle
Authié, E.Muteti, D.K.Williams, D.J.L.[Antibody responses to invariant antigens of Trypanosoma congolense in cattle of differing susceptibility to trypanosomiasis]Antibody responses to invariant antigens of Trypanosoma congolense in cattle of differing susceptibility to trypanosomiasis
Boulange, A.F.Authié, E.[A 69-KDa immunodominant antigen of Trypanosoma (Nannomonas) congolense is homologous to immunoglobulin heavy chain binding protein (Bip)]A 69-KDa immunodominant antigen of Trypanosoma (Nannomonas) congolense is homologous to immunoglobulin heavy chain binding protein (Bip)

Memory T- and B-cell responses to trypanosome antigens were measured in peripheral blood mononuclear cells, spleen and lymph node cells obtained from 4 trypanotolerant N'Dama cattle which had been exposed to 6 experimental infections with Trypanosoma congolense. These cattle were treated with try...


Lutje, V.Taylor, K.A.Boulange, A.F.Authié, E.[Trypanosoma congolense: Tissue distribution of long-term T- and B-cell responses in cattle]Trypanosoma congolense: Tissue distribution of long-term T- and B-cell responses in cattle
Authié, E.Duvallet, G.Robertson, C.Williams, D.J.L.[Antibody response to a 33 kDa cysteine protease of Trypanosoma congolense: Relationship to 'trypanotolerance' in cattle]Antibody response to a 33 kDa cysteine protease of Trypanosoma congolense: Relationship to 'trypanotolerance' in cattle
Williams, D.J.L.Logan-Henfrey, L.L.Authié, E.Seely, C.McOdimba, F.A.[Experimental infection with a haemorrhage-causing Trypanosoma vivax in N'Dama and Boran cattle]Experimental infection with a haemorrhage-causing Trypanosoma vivax in N'Dama and Boran cattle
Akol, G.W.O.Authié, E.Pinder, M.Moloo, S.K.Roelants, G.E.Murray, M.[Susceptibility and immune responses of Zebu and Taurine cattle of West Africa to infection with Trypanosoma congolense transmitted by Glossina morsitans centralis]Susceptibility and immune responses of Zebu and Taurine cattle of West Africa to infection with Trypanosoma congolense transmitted by Glossina morsitans centralis

T-cell-mediated immune responses to defined antigens of Trypanosoma congolense were measured in cattle undergoing primary infection. The antigens used were the variable surface glycoprotein and two invariant antigens, a 33-kDa cysteine protease (congopain) and a recombinant form of a 69-kDa heat-...


Lutje, V.Mertens, B.Boulange, A.F.Williams, D.J.L.Authié, E.[Trypanosoma congolense: Proliferative responses and interleukin production in lymph node cells of infected cattle]Trypanosoma congolense: Proliferative responses and interleukin production in lymph node cells of infected cattle

African animal trypanosomosis (nagana) is arguably the most important parasitic disease affecting livestock in sub-Saharan Africa. Since none of the existing control measures are entirely satisfactory, vaccine development is being actively pursued. However, due to antigenic variation, the quest f...


Boulange, A.F.Khamadi, S.A.Pillay, D.Coetzer, T.H.T.Authié, E.[Production of congopain, the major cysteine protease of Trypanosoma (Nannomonas) congolense, in Pichia pastoris reveals unexpected dimerization at physiological Ph]Production of congopain, the major cysteine protease of Trypanosoma (Nannomonas) congolense, in Pichia pastoris reveals unexpected dimerization at physiological Ph
Rowlands, G.J.Authié, E.D'Ieteren, G.D.M.Leak, S.G.A.Mulatu, W.Nagda, S.M.Peregrine, A.S.[An epidemiological study of recurrent trypanosome infection in East African Zebu cattle and its association with drug resistance]An epidemiological study of recurrent trypanosome infection in East African Zebu cattle and its association with drug resistance

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