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Williams, D.J.L.Logan-Henfrey, L.L.Authié, E.Seely, C.McOdimba, F.A.[Experimental infection with a haemorrhage-causing Trypanosoma vivax in N'Dama and Boran cattle]Experimental infection with a haemorrhage-causing Trypanosoma vivax in N'Dama and Boran cattle

A comparison of T-cell-mediated immune responses in trypanotolerant N'Dama and susceptible Boran cattle during primary infection with tsetse-transmitted Trypanosoma congolense was conducted to assess whether different patterns of T-cell activation occurred during trypanosome infection. Proliferat...


Lutje, V.Taylor, K.A.Kennedy, D.Authié, E.Boulange, A.F.Gettinby, G.[Trypanosoma congolense: A comparison of T-cell-mediated responses in lymph nodes of trypanotolerant and trypanosusceptible cattle during primary infection]Trypanosoma congolense: A comparison of T-cell-mediated responses in lymph nodes of trypanotolerant and trypanosusceptible cattle during primary infection

T-cell-mediated immune responses to defined antigens of Trypanosoma congolense were measured in cattle undergoing primary infection. The antigens used were the variable surface glycoprotein and two invariant antigens, a 33-kDa cysteine protease (congopain) and a recombinant form of a 69-kDa heat-...


Lutje, V.Mertens, B.Boulange, A.F.Williams, D.J.L.Authié, E.[Trypanosoma congolense: Proliferative responses and interleukin production in lymph node cells of infected cattle]Trypanosoma congolense: Proliferative responses and interleukin production in lymph node cells of infected cattle

Infections of cattle with tsetse-transmitted Trypanosoma congolense are accompanied by antibody responses to the variable surface glycoprotein (VSG) and to two major invariant antigens, a member of the hsp 70 family and a 33KDa cysteine protease. During primary infection, trypanotolerant N'Dama (...


Lutje, V.Authié, E.Boulange, A.F.Williams, D.J.L.[Bovine T-cell responses to defined Trypanosoma congolense antigens during infection]Bovine T-cell responses to defined Trypanosoma congolense antigens during infection

The trypanosome surface coat is composed almost entirely of a homogeneous array of molecules known as variable surface glycoproteins (VSG). These molecules are highly immunogenic and elicit a strong antibody response in the infected host. Antibodies against the surface-exposed epitopes of a parti...


Williams, D.J.L.Taylor, K.Newson, J.Naessens, JanAuthié, E.[Protective and inappropriate antibody responses in trypanosome-infected cattle]Protective and inappropriate antibody responses in trypanosome-infected cattle

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