Trypanosomes are covered with a dense layer of antigenically identical glycoproteins. These molecules are highly immunogenic and elicit an antibody response in the infected host. Antibodies against the surface-exposed epitopes of the trypanosome variable surface glycoproteins (VSG) mediate the de...
Williams, D.J.L.
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Taylor, K.
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Wilkie, B.
,
Gichuki, B.
,
Authié, E.
,
[Antibody responses to the surface-exposed epitopes of the trypanosome variable surface glycoprotein in N'Dama and Boran cattle]
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Antibody responses to the surface-exposed epitopes of the trypanosome variable surface glycoprotein in N'Dama and Boran cattle
Infections of cattle with tsetse-transmitted Trypanosoma congolense are accompanied by antibody responses to the variable surface glycoprotein (VSG) and to two major invariant antigens, a member of the hsp 70 family and a 33KDa cysteine protease. During primary infection, trypanotolerant N'Dama (...
Lutje, V.
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Authié, E.
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Boulange, A.F.
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Williams, D.J.L.
,
[Bovine T-cell responses to defined Trypanosoma congolense antigens during infection]
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Bovine T-cell responses to defined Trypanosoma congolense antigens during infection
The trypanosome surface coat is composed almost entirely of a homogeneous array of molecules known as variable surface glycoproteins (VSG). These molecules are highly immunogenic and elicit a strong antibody response in the infected host. Antibodies against the surface-exposed epitopes of a parti...
Williams, D.J.L.
,
Taylor, K.
,
Newson, J.
,
Naessens, Jan
,
Authié, E.
,
[Protective and inappropriate antibody responses in trypanosome-infected cattle]
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Protective and inappropriate antibody responses in trypanosome-infected cattle