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In order to test the hypothesis that trypanosome cysteine proteinases (CPs) contribute to pathology of trypanosomosis. cattle were immunised with CPl and/or CP2, the major Cps of Trypanosoma congolense, and subsequently challenged with T. congolense. Immunisation had no effect on the establishmen...


Authié, E.Boulange, A.F.Muteti, D.Lalmanach, G.Gauthier, F.Musoke, A.J.[Immunisation of cattle with cysteine proteinases of Trypanosoma congolense: Targetting the disease rather than the parasite]Immunisation of cattle with cysteine proteinases of Trypanosoma congolense: Targetting the disease rather than the parasite

The catalytic domains of two closely related cysteine proteinases (CP l and CP2) from Trypanosoma congolense, referred to as Cl and C2, were expressed as proforms in Escherichia coli (C 1) and in the baculovirus system (C I and C2). While the bacterial expression system did not allow recovery of ...


Boulange, A.F.Serveau, C.Brillard, M.Minet, C.Gauthier, F.Diallo, A.Lalmanach, G.Authié, E.[Functional expression of the catalytic domains of two cysteine proteinases from Trypanosoma congolense]Functional expression of the catalytic domains of two cysteine proteinases from Trypanosoma congolense

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