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A 69-kDa immunodominant protein of Trypanosoma congolense was identified as a member of the hsp70 family that is homologous to mammalian BiP. We report here the expression of the gene encoding the T. congolense BiP in a bacterial system. Dot blotting of the truncated recombinant proteins confirme...


Boulange, A.F.Katende, J.Authié, E.[Trypanosoma congolense: Expression of a heat shock protein 70 and initial evaluation as a diagnostic antigen for bovine trypanosomosis]Trypanosoma congolense: Expression of a heat shock protein 70 and initial evaluation as a diagnostic antigen for bovine trypanosomosis

The trypanosome surface coat is composed almost entirely of a homogeneous array of molecules known as variable surface glycoproteins (VSG). These molecules are highly immunogenic and elicit a strong antibody response in the infected host. Antibodies against the surface-exposed epitopes of a parti...


Williams, D.J.L.Taylor, K.Newson, J.Naessens, JanAuthié, E.[Protective and inappropriate antibody responses in trypanosome-infected cattle]Protective and inappropriate antibody responses in trypanosome-infected cattle

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