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Forty-three metabolites including several methoxylated flavonoids, tremetones, and ent-clerodane diterpenes were accurately identified for the first time in the ethanolic extract of P. quadrangularis by means of hyphenated UHPLC-quadrupole Orbitrap mass spectrometry, and seven isolated compounds ...


Ardiles, A.Barrientos, R.Simirgiotis, M.J.Bórquez, J.Sepúlveda, B.Areche, C.[Gastroprotective activity of Parastrephia quadrangularis (Meyen), cabrera from the atacama desert]Gastroprotective activity of Parastrephia quadrangularis (Meyen), cabrera from the atacama desert

High-resolution mass spectrometry is currently used to determine the mass of biologically active compounds in plants and UHPLC-Orbitrap is a relatively new technology that allows fast fingerprinting and metabolomics analysis. In this work, several phenolic compounds including eleven phenolic acid...


Simirgiotis, M.J.Quispe, C.Mocan, A.Villatoro, J.M.Areche, C.Bórquez, J.Sepúlveda, B.Echiburu-Chau, C.[UHPLC high resolution orbitrap metabolomic fingerprinting of the unique species Ophryosporus triangularis meyen from the atacama desert, Northern Chile]UHPLC high resolution orbitrap metabolomic fingerprinting of the unique species Ophryosporus triangularis meyen from the atacama desert, Northern Chile

UHPLC/ESI/MS identification of organic compounds is the first step in the majority of screening techniques for the characterization of biologically active metabolites in natural sources. This paper describes a method for the fast identification and characterisation of secondary metabolites in Lep...


Jiménez-González, A.Quispe, C.Bórquez, J.Sepúlveda, B.Riveros, F.Areche, C.Nagles, E.García-Beltrán, O.Simirgiotis, M.J.[UHPLC-ESI-ORBITRAP-MS analysis of the native Mapuche medicinal plant palo negro (Leptocarpha rivularis DC.–Asteraceae) and evaluation of its antioxidant and cholinesterase inhibitory properties]UHPLC-ESI-ORBITRAP-MS analysis of the native Mapuche medicinal plant palo negro (Leptocarpha rivularis DC.–Asteraceae) and evaluation of its antioxidant and cholinesterase inhibitory properties

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