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Resistance to nematode parasites can be improved by selection, but efforts to include appropriate traits in commercial livestock breeding programs are only a recent development. Procedures for including resistance in breeding programs are similar to those involving other traits. The steps are des...


Woolaston, R.R.Baker, R.L.[Prospects of breeding small ruminants for resistance to internal parasites]Prospects of breeding small ruminants for resistance to internal parasites

Red Maasai and Dorper sheep were evaluated for their resistance to gastro-intestinal (GI) nematode parasites (predominantly Haemonchus contortus), productivity and productive efficiency (assessed on a metabolizable energy basis) in experiments undertaken at the Kenyan coast (sub-humid environment...


Baker, R.L.Mugambi, J.M.M.Audho, James O.Carles, A.B.Thorpe, W.R.[Genotype by environment interactions for productivity and resistance to gastro-intestinal nematode parasites in Red Maasai and Dorper sheep]Genotype by environment interactions for productivity and resistance to gastro-intestinal nematode parasites in Red Maasai and Dorper sheep

This paper reports the results of a genome-wide search for quantitative trait loci (QTL) influencing immunological responses to infection with the gastro-intestinal nematode parasite Heligmosomoides polygyrus in an F2 population created by crossing the resistant SWR and the susceptible CBA inbr...


Menge, D.M.Behnke, J.M.Lowe, A.Gibson, John P.Iraqi, F.A.Baker, R.L.Wakelin, D.[Mapping of chromosomal regions influencing immunological responses to gastrointestinal nematode infections in mice]Mapping of chromosomal regions influencing immunological responses to gastrointestinal nematode infections in mice

A study was carried out at the International Livestock Research Institute (ILRI) Debre Berhan Research Station in Ethiopia from 1992 to 1995 to compare the peri-parturient rise (PPR) in faecal nematode egg counts (FEC) in ewes of two indigenous sheep breeds. A total of 1439 Menz and 1347 Horro ew...


Tembely, S.Lahlou-Kassi, A.Rege, J.E.O.Mukasa-Mugerwa, E.Anindo, D.O.Sovani, S.Baker, R.L.[Breed and season effects on the peri-parturient rise in nematode egg output in indigenous ewes in a cool tropical environment]Breed and season effects on the peri-parturient rise in nematode egg output in indigenous ewes in a cool tropical environment

The host-protective immune response to infection with gastrointestinal (GI) nematodes involves a range of interacting processes that begin with recognition of the parasite's antigens and culminate in an inflammatory reaction in the intestinal mucosa. Precisely which immune effectors are responsib...


Behnke, J.M.Iraqi, F.A.Menge, D.Baker, R.L.Gibson, John P.Wakelin, D.[Chasing the genes that control resistance to gastrointestinal nematodes]Chasing the genes that control resistance to gastrointestinal nematodes

Six first cross (F1) Red Maasai X Dorper rams were mated to both Red Maasai (R) and Dorper (D) ewes to produce 1342 double backcross progeny (672 3/4 D/1/4 R and 670 3/4 R/1/4 D lambs born alive). These six double backcross resource families are being used to identify quantitative trait loci con...


Mugambi, J.M.M.Audho, James O.Baker, R.L.[Evaluation of the phenotypic performance of a Red Maasai and Dorper double backcross resource population: Natural pasture challenge with gastro-intestinal nematode parasites]Evaluation of the phenotypic performance of a Red Maasai and Dorper double backcross resource population: Natural pasture challenge with gastro-intestinal nematode parasites

Parasitic nematodes are among the most common and economically important infectious diseases of grazing livestock, especially in small ruminants in the tropics and subtropics in Kenya the control of gastrointestinal nematode infections in sheep and goats is usually made with synthetic anthelmin...


Githiori, J.B.Hoglund, J.Waller, P.J.Baker, R.L.[Evaluation of anthelmintic properties of extracts from some plants used as livestock dewormers by pastoralist and smallholder farmers in Kenya against Heligmosomoides polygyrus infections in mice]Evaluation of anthelmintic properties of extracts from some plants used as livestock dewormers by pastoralist and smallholder farmers in Kenya against Heligmosomoides polygyrus infections in mice

Albizia anthelmintica Brong., belongs to the plant family Mimosaceae. The plant is widely used in East Africa by poor smallholder farmers and pastoralists to treat their livestock against internal parasites. The anthelmintic effects of water extracts from the bark of A. anthelmintica, obtained f...


Githiori, J.B.Hoglund, J.Waller, P.J.Baker, R.L.[The anthelmintic efficacy of the plant, Albizia anthelmintica, against the nematode parasites Haemonchus contortus of sheep and Heligmosomoides polygyrus of mice]The anthelmintic efficacy of the plant, Albizia anthelmintica, against the nematode parasites Haemonchus contortus of sheep and Heligmosomoides polygyrus of mice

Since the publication of the mouse genome, attention has focused on the strains that were selected for sequencing. In this paper we report the results of experiments that characterized the response to infection with the murine gastrointestinal nematode Heligmosomoides polygyrus of eight new strai...


Behnke, J.M.Mugambi, J.M.M.Clifford, S.Iraqi, F.A.Baker, R.L.Gibson, John P.Wakelin, D.[Genetic variation in resistance to repeated infections with Heligmosomoides polygyrus bakeri, in inbred mouse strains selected for the mouse genome project]Genetic variation in resistance to repeated infections with Heligmosomoides polygyrus bakeri, in inbred mouse strains selected for the mouse genome project

The effects of breed and dietary protein supplementation on the development of resistance and resilience to gastrointestinal nematode parasites (endoparasites) were examined in artificially infected Horro and Menz lambs from 4 to 12 months of age. The factorial design involved two breeds, two inf...


Haile, AynalemTembely, S.Anindo, D.O.Mukasa-Mugerwa, E.Rege, J.E.O.Yami, A.Baker, R.L.[Effects of breed and dietary protein supplementation on the responses to gastro intestinal nematode infections in Ethiopian sheep]Effects of breed and dietary protein supplementation on the responses to gastro intestinal nematode infections in Ethiopian sheep

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