This paper reports the results of a genome-wide search for quantitative trait loci (QTL) influencing immunological responses to infection with the gastro-intestinal nematode parasite Heligmosomoides polygyrus in an F2 population created by crossing the resistant SWR and the susceptible CBA inbr...
Menge, D.M.
,
Behnke, J.M.
,
Lowe, A.
,
Gibson, John P.
,
Iraqi, F.A.
,
Baker, R.L.
,
Wakelin, D.
,
[Mapping of chromosomal regions influencing immunological responses to gastrointestinal nematode infections in mice]
,
Mapping of chromosomal regions influencing immunological responses to gastrointestinal nematode infections in mice
Quantitative trait loci (QTL) associated with resistance to an intestinal worm in a well-defined murine model are described. These have been identified in an F(2) population derived from resistant (SWR) and susceptible (CBA) parental mouse strains infected with the gastro-intestinal nematode par...
Breeds of cattle, sheep and goats have been identified which are genetically resistant and/or tolerant to gastro-intestinal nematode parasites. Mapping and cloning of resistant genes will facilitate Development of new breeds of livestock, which combine this important disease resistance trait with...