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Micronutrient malnutrition affects more than half of the world population, particularly in developing countries. Concerted international and national fortification and supplementation efforts to curb the scourge of micronutrient malnutrition are showing a positive impact, alas without reaching th...


Mayer, Jorge EdgardPfeiffer, Wolfgang H.Beyer, Peter[Biofortified crops to alleviate micronutrient malnutrition]Biofortified crops to alleviate micronutrient malnutrition
Chavarriaga Aguirre, PaulLadino Franco, YJBeltrán Giraldo, Jorge AlonsoVacca, OLópez, D.García, M.Chávez, Alba L.Arango Mejía, J.Beyer, PeterAl-Babili, S.Tohme, Joseph M.[Transgenic cassava with bacterial genes of the carotenoid biosynthetic pathway accumulate higher levels of phytoene, lutein and a and b-carotene]Transgenic cassava with bacterial genes of the carotenoid biosynthetic pathway accumulate higher levels of phytoene, lutein and a and b-carotene

Cassava (Manihot esculenta) is an important staple crop, especially in the arid tropics. Because roots of commercial cassava cultivars contain a limited amount of provitamin A carotenoids, both conventional breeding and genetic modification are being applied to increase their production and accum...


Welsch, RArango, JacoboBar, CSalazar, BAl-Babili, S.Beltrán Giraldo, Jorge AlonsoChavarriaga Aguirre, PaulCeballos, H.Tohme, Joseph M.Beyer, Peter[Provitamin A accumulation in Cassava (Manihot esculenta) roots driven by a single nucleotide polymorphism in a phytoene synthase gene[W]]Provitamin A accumulation in Cassava (Manihot esculenta) roots driven by a single nucleotide polymorphism in a phytoene synthase gene[W]

A prerequisite for biotechnological improvements of storage roots is the availability of tissue-specific promoters enabling high expression of transgenes. In this work, we cloned two genomic fragments, pMe1 and pDJ3S, controlling the expression of a gene with unknown function from cassava (Maniho...


Arango Mejía, J.Salazar, BWelsch, RSarmiento Salazar, FBeyer, PeterAl-Babili, S.[Putative storage root specific promoters from cassava and yam : Cloning and evaluation in transgenic carrots as a model system]Putative storage root specific promoters from cassava and yam : Cloning and evaluation in transgenic carrots as a model system
Schaub, PatrickWüst, FlorianKoschmieder, JulianYu, QiujuVirk, Parminder SinghTohme, Joseph M.Beyer, Peter[Nonenzymatic β-Carotene Degradation in Provitamin A-Biofortified Crop Plants]Nonenzymatic β-Carotene Degradation in Provitamin A-Biofortified Crop Plants
Arango, JacoboJourdan, MatthieuGeoffriau, EmmanuelBeyer, PeterWelsch, Ralf[Carotene hydroxylase activity determines the levels of both a-carotene and total carotenoids in orange carrots]Carotene hydroxylase activity determines the levels of both a-carotene and total carotenoids in orange carrots

A major constraint for incorporating new traits into cassava using biotechnology is the limited list of known/tested promoters that encourage the expression of transgenes in the cassava’s starchy roots. Based on a previous report on the glutamic-acid-rich protein Pt2L4, indicating a preferential ...


Beltrán Giraldo, Jorge AlonsoPrias, MAl-Babili, S.Ladino Franco, YJLópez, D.Beyer, PeterChavarriaga Aguirre, PaulTohme, Joseph M.[Expression pattern conferred by a glutamic acid-rich protein gene promoter in field-grown transgenic cassava (Manihot esculenta Crantz)]Expression pattern conferred by a glutamic acid-rich protein gene promoter in field-grown transgenic cassava (Manihot esculenta Crantz)
Beltrán Giraldo, Jorge AlonsoLadino Franco, YJVacca, OLópez, D.Arango Mejía, J.Chávez, Alba L.Al-Babili, S.Beyer, PeterChavarriaga Aguirre, PaulTohme, Joseph M.[Increasing phytoene and B-carotene content in cassava roots by expression of an exognous phytoene synthase (CrtB) gene]Increasing phytoene and B-carotene content in cassava roots by expression of an exognous phytoene synthase (CrtB) gene
Chavarriaga Aguirre, PaulBeltrán Giraldo, Jorge AlonsoLadino Franco, YJVacca, OLópez, D.Arango Mejía, J.Al-Babili, S.Beyer, PeterTohme, Joseph M.[Multiple strategies to enhance the accumulation of pro-Vit A in cassava roots]Multiple strategies to enhance the accumulation of pro-Vit A in cassava roots
Beltrán Giraldo, Jorge AlonsoLadino Franco, YJVacca, OLópez, D.Al-Babili, S.Beyer, PeterChavarriaga Aguirre, PaulTohme, Joseph M.[Partial functional characterization of the promoters CP1+ and CP2-, derived from a cassava glutamic acid-rich protein gene, in cassava and carrot transgenic plants]Partial functional characterization of the promoters CP1+ and CP2-, derived from a cassava glutamic acid-rich protein gene, in cassava and carrot transgenic plants

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