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Bishop, Richard P.Sohanpal, B.K.Morzaria, S.P.[Theileria parva: Detection of genomic polymorphisms by polymerase chain reaction amplification of DNA using arbitrary primers]Theileria parva: Detection of genomic polymorphisms by polymerase chain reaction amplification of DNA using arbitrary primers

Immunity to infection by the protozoan parasite Theileria parva in cattle is partially attributable to cytotoxic T cells, which kill lymphocytes infected with the schizont stage of the parasite. Here we evaluated five stocks of buffalo-derived T. parva lawrencei parasites and two stocks of cattle...


Kariuki, T.M.Grootenhuis, J.G.Dolan, T.T.Bishop, Richard P.Baldwin, C.L.[Immunization with Theileria parva parasites from buffaloes results in generation of cytotoxic T cells which recognize antigens common among cells infected with stocks of T. parva parva, T. parva bovis, and T. parva lawrencei]Immunization with Theileria parva parasites from buffaloes results in generation of cytotoxic T cells which recognize antigens common among cells infected with stocks of T. parva parva, T. parva bovis, and T. parva lawrencei

Heterologous priming-boosting vaccination regimens involving priming with plasmid DNA antigen constructs and inoculating (boosting) with the same recombinant antigen expressed in replication-attenuated poxviruses have recently been demonstrated to induce immunity, based on CD4(+)- and CD8(+)-T-c...


Taracha, E.L.N.Bishop, Richard P.Musoke, A.J.Hill, A.V.S.Gilbert, S.C.[Heterologous priming-boosting immunization of cattle with Mycobacterium tuberculosis 85A induces antigen-specific T-cell responses]Heterologous priming-boosting immunization of cattle with Mycobacterium tuberculosis 85A induces antigen-specific T-cell responses

A stage-specific surface antigen of Theileria parva, p67, is the basis for the development of an anti-sporozoite vaccine for the control of East Coast fever (ECF) in cattle. By Pepscan analysis with a series of overlapping synthetic p67 peptides, the antigen was shown to contain five distinct lin...


Nene, VishvanathGobright, E.I.Bishop, Richard P.Morzaria, S.P.Musoke, A.J.[Linear peptide specificity of bovine antibody responses to p67 of Theileria parva and sequence diversity of sporozoite-neutralising epitopes: Implications for a vaccine]Linear peptide specificity of bovine antibody responses to p67 of Theileria parva and sequence diversity of sporozoite-neutralising epitopes: Implications for a vaccine
Bishop, Richard P.Sohanpal, B.K.Morzaria, S.P.[Cloning and characterisation of a repetitive DNA sequence from Theileria mutans. Application as a species-specific probe]Cloning and characterisation of a repetitive DNA sequence from Theileria mutans. Application as a species-specific probe
Stagg, D.A.Bishop, Richard P.Morzaria, S.P.Shaw, M.K.Wesonga, D.Orinda, G.O.Grootenhuis, J.G.Molyneux, D.H.Young, A.S.[Characterization of Theileria parva which infects water buck (Kobus defassa)]Characterization of Theileria parva which infects water buck (Kobus defassa)

The discipline of genomics is setting new paradigms in research approaches to resolving problems in human and animal health. We propose to determine the genome sequence of Theileria parva, a pathogen of cattle, using the random shotgun approach pioneered at The Institute for Genomic Research (TIG...


Nene, VishvanathBishop, Richard P.Morzaria, S.P.Gardner, M.J.Sugimoto, C.Ole-MoiYoi, O.K.Fraser, C.M.Irvin, A.[Theileria parva genomics reveals an atypical apicomplexan genome]Theileria parva genomics reveals an atypical apicomplexan genome
Bishop, Richard P.Sohanpal, B.K.Spooner, P.R.Dolan, T.T.Allsopp, B.A.Morzaria, S.P.[Detection of polymorphisms among Theileria parva stocks using repetitive, telomeric ribosomal DNA probes and anti-schizont monoclonal antibodies]Detection of polymorphisms among Theileria parva stocks using repetitive, telomeric ribosomal DNA probes and anti-schizont monoclonal antibodies

The role of the ancestral sylvatic cycle of the African swine fever virus (ASFV) is not well understood in the endemic areas of eastern Africa. We therefore analysed the ASF infection status on samples collected from 51 free-ranging warthogs (Phacocherus africanus) and 1576 Ornithodorus porcinus ...


Gallardo, C.Okoth, S.Pelayo, V.Anchuelo, R.Martin, E.Simon, A.Llorente, A.Nieto, R.Soler Garzón, AlvaroMartin, R.Arias, MarisaBishop, Richard P.[African swine fever viruses with two different genotypes, both of which occur in domestic pigs, are associated with ticks and adult warthogs, respectively, at a single geographical site]African swine fever viruses with two different genotypes, both of which occur in domestic pigs, are associated with ticks and adult warthogs, respectively, at a single geographical site

African swine fever virus p72 genotype IX, associated with outbreaks in eastern Africa, is cocirculating in the Republic of the Congo with West African genotype I. Data suggest that viruses from eastern Africa are moving into western Africa, increasing the threat of outbreaks caused by novel viru...


Gallardo, C.Anchuelo, R.Pelayo, V.Poudevigne, F.León, T.Nzoussi, J.Bishop, Richard P.Pérez, C.Soler Garzón, AlvaroNieto, R.Martín, H.Arias, Marisa[African Swine Fever Virus p72 Genotype IX in Domestic Pigs, Congo, 2009]African Swine Fever Virus p72 Genotype IX in Domestic Pigs, Congo, 2009

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