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Silatsa, Barberine A.Simo, GustaveGithaka, Naftaly W.Mwaura, StephenKamga, Rolin M.Oumarou, FariikouTiambo, Christian K.Bishop, Richard P.Djikeng, AppolinaireKuiate, Jules-RogerNjiokou, FlobertPelle, Roger[A comprehensive survey of the prevalence and spatial distribution of ticks infesting cattle in different agro-ecological zones of Cameroon]A comprehensive survey of the prevalence and spatial distribution of ticks infesting cattle in different agro-ecological zones of Cameroon

A stochastic model designed to simulate transmission dynamics of African swine fever virus (ASFV) in a free-ranging pig population under various intervention scenarios is presented. The model was used to assess the relative impact of the timing of the implementation of different control strategie...


Barongo, M.B.Bishop, Richard P.Fèvre, Eric M.Knobel, D.L.Ssematimba, A.[A mathematical model that simulates control options for African swine fever virus (ASFV)]A mathematical model that simulates control options for African swine fever virus (ASFV)

Reassociation kinetics and flow cytometry data indicate that ixodid tick genomes are large, relative to most arthropods, containing ≥ 109 base pairs. The molecular basis for this is unknown. We have identified a novel small interspersed element with features of a tRNA-derived SINE, designated Ruk...


Sunter, J.D.Patel, S.P.Skilton, Robert A.Knowles, Donald P.Scoles, Glen A.Nene, VishvanathVilliers, Etienne P. deBishop, Richard P.[A novel SINE family occurs frequently in both genomic DNA and transcribed sequences in ixodid ticks of the arthropod sub-phylum Chelicerata]A novel SINE family occurs frequently in both genomic DNA and transcribed sequences in ixodid ticks of the arthropod sub-phylum Chelicerata

Vaccines based on recombinant Bm86 gut antigen from Boophilus microplus are a useful component of integrated control strategies against B. microplus infestations of cattle. The capacity of such vaccines to control heterologous infestations by two African tick species was investigated. The mean we...


Odongo, D.Kamau, L.Skilton, Robert A.Mwaura, S.Nitsch, C.Musoke, A.J.Taracha, E.A.Daubenberger, C.A.Bishop, Richard P.[Vaccination of cattle with TickGARD induces cross-reactive antibodies binding to conserved linear peptides of Bm86 homologues in Boophilus decoloratus]Vaccination of cattle with TickGARD induces cross-reactive antibodies binding to conserved linear peptides of Bm86 homologues in Boophilus decoloratus

Previous studies using monoclonal antibody (mAb) 4C9 specific for a 32 kDa antigen (p32) of Theileria parva demonstrated expression of the antigen on the surface of the sporozoite, making it a potential antigen for sporozoite neutralization. A full-length cDNA encoding the major merozoite/piropla...


Skilton, Robert A.Musoke, A.J.Wells, C.W.Yagi, Y.Nene, VishvanathSpooner, P.R.Gachanja, J.Osaso, J.Bishop, Richard P.Morzaria, S.P.[A 32 kDa surface antigen of Theileria parva: Characterization and immunization studies]A 32 kDa surface antigen of Theileria parva: Characterization and immunization studies

Immunity against the bovine protozoan parasite Theileria parva has previously been shown to be mediated through lysis of parasite-infected cells by MHC class I restricted CD8+ cytotoxic T lymphocytes. It is hypothesized that identification of CTL target schizont antigens will aid the development ...


Graham, S.P.Honda, Y.Pelle, RogerMwangi, D.M.Glew, E.J.Villiers, Etienne P. deShah, TushaarBishop, Richard P.Bruggen, P. van derNene, VishvanathTaracha, E.L.N.[A novel strategy for the identification of antigens that are recognised by bovine MHC class I restricted cytotoxic T cells in a protozoan infection using reverse vaccinology]A novel strategy for the identification of antigens that are recognised by bovine MHC class I restricted cytotoxic T cells in a protozoan infection using reverse vaccinology

Background The ixodid tick Rhipicephalus appendiculatus transmits the apicomplexan protozoan parasite Theileria parva,which causes East coast fever (ECF), the most economically important cattle disease in eastern and southern Africa. Recent analysis of micro- and minisatellite markers showed an a...


Kanduma, E.G.Mwacharo, Joram M.Githaka, Naftaly W.Kinyanjui, P.W.Njuguna, J.Kamau, L.M.Kariuki, E.Mwaura, S.Skilton, Robert A.Bishop, Richard P.[Analyses of mitochondrial genes reveal two sympatric but genetically divergent lineages of Rhipicephalus appendiculatus in Kenya]Analyses of mitochondrial genes reveal two sympatric but genetically divergent lineages of Rhipicephalus appendiculatus in Kenya

Rab genes encode a subgroup of small GTP-binding proteins within the ras super-family that regulate targeting and fusion of transport vesicles within the secretory and endocytic pathways. These genes are of particular interest in the protozoan phylum Apicomplexa, since a family of Rab GTPases has...


Langsley, G.Noort, V. vanCarret, C.Meissner, M.Villiers, Etienne P. deBishop, Richard P.Pain, A.[Comparative genomics of the Rab protein family in Apicomplexan parasites]Comparative genomics of the Rab protein family in Apicomplexan parasites

Bishop, Richard P.Okoth, S.Davies, J.[Epidemiology of African Swine Fever: A prerequisite to control]Epidemiology of African Swine Fever: A prerequisite to control
Bishop, Richard P.Musoke, A.J.Skilton, Robert A.Morzaria, S.P.Gardner, M.Nene, Vishvanath[Theileria: Life cycle stages associated with the ixodid tick vector]Theileria: Life cycle stages associated with the ixodid tick vector

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