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The infection-and-treatment method (ITM) for immunization of cattle against East Coast fever has historically been used only on a limited scale because of logistical and policy constraints. Recent large-scale deployment among pastoralists in Tanzania has stimulated demand. Concurrently, a suite o...


Giulio, Giuseppe diLynen, GodelieveMorzaria, S.P.Oura, C.Bishop, Richard P.[Live immunization against East Coast fever - current status]Live immunization against East Coast fever - current status

The preparation of Theileria parva stabilates has been described by Cunningham et al (1973). The method is detailed in the FAO report (1978) and the FAO tick and tick-borne Disease Manual (1984). Theileria parva stabilates are a source of viable sporozoites that can be used to immunise cattle by ...


Morzaria, S.P.Spooner, P.R.Bishop, Richard P.Mwaura, S.[The preparation of a composite stabilate for immunisation against East Coast fever]The preparation of a composite stabilate for immunisation against East Coast fever

The "Muguga cocktail" live vaccine comprises three Theileria parva stocks (Muguga, Kiambu 5 and the buffalo-derived Serengeti-transformed) and has been used extensively in Eastern, Central and Southern Africa with an infection and treatment protocol to protect cattle against East Coast fever. We ...


Oura, C.A.L.Bishop, Richard P.Wampande, E.M.Lubega, G.W.Tait, A.[The persistence of component Theileria parva stocks in cattle immunized with the ‘Muguga cocktail’ live vaccine against East Coast fever in Uganda]The persistence of component Theileria parva stocks in cattle immunized with the ‘Muguga cocktail’ live vaccine against East Coast fever in Uganda

The primary goals of applying molecular tools, developed at ILRI in conjunction with the use of infection and treatment immunisation are quality control of vaccines; monitoring of possible vaccine breakthrough and breakdown; and assessment of the impact of introducing new parasite types on long-t...


Bishop, Richard P.Nene, VishvanathSpooner, P.R.Mbogo, S.Kariuki, D.Payne, R.Morzaria, S.P.[Application of molecular tools in support of deployment of Theileria parva live vaccines]Application of molecular tools in support of deployment of Theileria parva live vaccines

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