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Article 2017-05

ALS skeletal muscle shows enhanced TGF-β signaling, fibrosis and induction of fibro/adipogenic progenitor markers

Autor: Gonzalez, D. Contreras, O. Rebolledo, D.L. Espinoza, J.P. Van Zundert, B. Brandan, E.

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease in which upper and lower motoneurons degenerate leading to muscle wasting, paralysis and eventually death from respiratory failure. Several studies indicate that skeletal muscle contributes to disease progression; however th...

Enlace original: http://repositorio.unab.cl/xmlui/handle/ria/4721

Repositorio Universidad Andrés Bello

Adipogenesis

Amyotrophic Lateral Sclerosis

Animals

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Gonzalez, D. , Contreras, O. , Rebolledo, D.L. , Espinoza, J.P. , Van Zundert, B. , Brandan, E. , [ALS skeletal muscle shows enhanced TGF-β signaling, fibrosis and induction of fibro/adipogenic progenitor markers] , ALS skeletal muscle shows enhanced TGF-β signaling, fibrosis and induction of fibro/adipogenic progenitor markers

Artículo 2014

Andrographolide attenuates skeletal muscle dystrophy in mdx mice and increases efficiency of cell therapy by reducing fibrosis

Autor: Cabrera, D. Gutiérrez, J. Cabello-Verrugio, C. Morales, M. G. Mezzano, S. Fadic, R. Casar, J. C. Hancke, J. L. Brandan, E.

Background: Duchenne muscular dystrophy (DMD) is characterized by the absence of the cytoskeletal protein dystrophin, muscle wasting, increased transforming growth factor type beta (TGF-β) signaling, and fibrosis. At the present time, the only clinically validated treatments for DMD are glucocort...

Enlace original: https://repositorio.uc.cl/handle/11534/27461 https://repositorio.uc.cl/handle/11534/27461

Repositorio UC

Andrographolide

Cell therapy

DMD

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Cabrera, D. , Gutiérrez, J. , Cabello-Verrugio, C. , Morales, M. G. , Mezzano, S. , Fadic, R. , Casar, J. C. , Hancke, J. L. , Brandan, E. , [Andrographolide attenuates skeletal muscle dystrophy in mdx mice and increases efficiency of cell therapy by reducing fibrosis] , Andrographolide attenuates skeletal muscle dystrophy in mdx mice and increases efficiency of cell therapy by reducing fibrosis

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ALS skeletal muscle shows enhanced TGF-β signaling, fibrosis and induction of fibro/adipogenic progenitor markers

Andrographolide attenuates skeletal muscle dystrophy in mdx mice and increases efficiency of cell therapy by reducing fibrosis

Descubre y comparte nuestro conocimiento público

Resultados de búsqueda

ALS skeletal muscle shows enhanced TGF-β signaling, fibrosis and induction of fibro/adipogenic progenitor markers

[Gonzalez_D_ALS_skeletal_muscle.pdf]

Andrographolide attenuates skeletal muscle dystrophy in mdx mice and increases efficiency of cell therapy by reducing fibrosis

[Andrographolide attenuates skeletal muscle dystrophy in mdx mice and increases efficiency of cell therapy by reducing fibrosis.pdf]