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Article 2016-04

Autor: Morales, M.G. Abrigo, J. Acuna, M.J. Santos, R.A. Bader, M. Brandan, E. Simon, F. Olguin, H. Cabrera, D. Cabello-Verrugio, C.

Immobilization is a form of disuse characterized by a loss of strength and muscle mass. Among the main features are decreased IGF-1/Akt signalling and increased ubiquitin-proteasome pathway signalling, which induce greater myosin heavy chain degradation. Activation of the classical renin-angioten...

Enlace original: http://repositorio.unab.cl/xmlui/handle/ria/3994

Repositorio Universidad Andrés Bello
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Morales, M.G. ,  Abrigo, J. ,  Acuna, M.J. ,  Santos, R.A. ,  Bader, M. ,  Brandan, E. ,  Simon, F. ,  Olguin, H. ,  Cabrera, D. ,  Cabello-Verrugio, C. ,  [Angiotensin-(1-7) attenuates disuse skeletal muscle atrophy in mice via its receptor, Mas] ,  Angiotensin-(1-7) attenuates disuse skeletal muscle atrophy in mice via its receptor, Mas
Article 2017-06

Autor: Cabrera, D. Wree, A. Povero, D. Solís, N. Hernandez, A. Pizarro, M. Moshage, H. Torres, J. Feldstein, A.E. Cabello-Verrugio, C. Brandan, E. Barrera, F. Arab, J.P. Arrese, M.

Therapy for nonalcoholic steatohepatitis (NASH) is limited. Andrographolide (ANDRO), a botanical compound, has a potent anti-inflammatory activity due to its ability to inhibit NF-κB. ANDRO has been also shown to inhibit the NLRP3 inflammasome, a relevant pathway in NASH. Our aim was to evaluate ...

Enlace original: http://repositorio.unab.cl/xmlui/handle/ria/4736

Repositorio Universidad Andrés Bello
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Cabrera, D. ,  Wree, A. ,  Povero, D. ,  Solís, N. ,  Hernandez, A. ,  Pizarro, M. ,  Moshage, H. ,  Torres, J. ,  Feldstein, A.E. ,  Cabello-Verrugio, C. ,  Brandan, E. ,  Barrera, F. ,  Arab, J.P. ,  Arrese, M. ,  [Andrographolide Ameliorates Inflammation and Fibrogenesis and Attenuates Inflammasome Activation in Experimental Non-Alcoholic Steatohepatitis] ,  Andrographolide Ameliorates Inflammation and Fibrogenesis and Attenuates Inflammasome Activation in Experimental Non-Alcoholic Steatohepatitis
Article 2017-05

Autor: Gonzalez, D. Contreras, O. Rebolledo, D.L. Espinoza, J.P. Van Zundert, B. Brandan, E.

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease in which upper and lower motoneurons degenerate leading to muscle wasting, paralysis and eventually death from respiratory failure. Several studies indicate that skeletal muscle contributes to disease progression; however th...

Enlace original: http://repositorio.unab.cl/xmlui/handle/ria/4721

Repositorio Universidad Andrés Bello
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Gonzalez, D. ,  Contreras, O. ,  Rebolledo, D.L. ,  Espinoza, J.P. ,  Van Zundert, B. ,  Brandan, E. ,  [ALS skeletal muscle shows enhanced TGF-β signaling, fibrosis and induction of fibro/adipogenic progenitor markers] ,  ALS skeletal muscle shows enhanced TGF-β signaling, fibrosis and induction of fibro/adipogenic progenitor markers

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