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The neglected tropical diseases (NTDs) are characterized by their tendency to cluster within groups of people, typically the poorest and most marginalized. Despite this, measures of clustering, such as within-group correlation or between-group heterogeneity, are rarely reported from community-bas...


Glanville, William A. deThomas, Lian F.Cook, Elizabeth A.J.Bronsvoort, B.M. de C.Wardrop, N.Wamae, C.N.Kariuki, S.Fèvre, Eric M.[General contextual effects on neglected tropical disease risk in rural Kenya]General contextual effects on neglected tropical disease risk in rural Kenya

Many individual hosts are infected with multiple parasite species, and this may increase or decrease the pathogenicity of the infections. This phenomenon is termed heterologous reactivity and is potentially an important determinant of both patterns of morbidity and mortality and of the impact of ...


Woolhouse, Mark E.J.Thumbi, S.M.Jennings, A.Chase-Topping, M.Callaby, R.Kiara, Henry K.Oosthuizen, M.C.Mbole-Kariuki, Mary N.Conradie, I.Handel, I.G.Poole, Elizabeth J.Njiiri, E.Collins, N.E.Murray, G.Tapio, M.Auguet, O.T.Weir, W.Morrison, W. IvanKruuk, L.E.B.Bronsvoort, B.M. de C.Hanotte, Olivier H.Coetzer, K.Toye, Philip G.[Co-infections determine patterns of mortality in a population exposed to parasite infection]Co-infections determine patterns of mortality in a population exposed to parasite infection

Tick-borne diseases are a major impediment to improved productivity of livestock in sub-Saharan Africa. Improved control of these diseases would be assisted by detailed epidemiological data. Here we used longitudinal, serological data to determine the patterns of exposure to Theileria parva, Thei...


Kiara, Henry K.Jennings, A.Bronsvoort, B.M. de C.Hande, I.G.Mwangi, S.T.Mbole-Kariuki, Mary N.Wyk, I.C. vanPoole, Elizabeth J.Hanotte, Olivier H.Coetzer, J.A.W.Woolhouse, Mark E.J.Toye, Philip G.[A longitudinal assessment of the serological response to Theileria parva and other tick-borne parasites from birth to one year in a cohort of indigenous calves in western Kenya]A longitudinal assessment of the serological response to Theileria parva and other tick-borne parasites from birth to one year in a cohort of indigenous calves in western Kenya

Parasite burden varies widely between individuals within a population, and can covary with multiple aspects of individual phenotype. Here we investigate the sources of variation in faecal strongyle eggs counts, and its association with body weight and a suite of haematological measures, in a coho...


Callaby, R.Hanotte, Olivier H.Wyk, I.C. vanKiara, Henry K.Toye, Philip G.Mbole-Kariuki, Mary N.Jennings, A.Thumbi, S.M.Coetzer, J.A.W.Bronsvoort, B.M. de C.Knott, S.A.Woolhouse, Mark E.J.Kruuk, L.E.B.[Variation and covariation in strongyle infection in East African shorthorn zebu calves]Variation and covariation in strongyle infection in East African shorthorn zebu calves

Most studies of infectious diseases in East African cattle have concentrated on gastro-intestinal parasites and vector-borne diseases. As a result, relatively little is known about viral diseases, except for those that are clinically symptomatic or which affect international trade such as foot an...


Callaby, R.Toye, Philip G.Jennings, A.Thumbi, S.M.Wyk, I.C. vanHanotte, Olivier H.Mbole-Kariuki, Mary N.Bronsvoort, B.M. de C.Kruuk, L.E.B.Woolhouse, Mark E.J.Kiara, Henry K.[Seroprevalence of respiratory viral pathogens of indigenous calves in western Kenya]Seroprevalence of respiratory viral pathogens of indigenous calves in western Kenya
Scolamacchia, F.Handel, I.G.Fèvre, Eric M.Morgan, K.L.Tanya, V.N.Bronsvoort, B.M. de C.[Serological patterns of brucellosis, leptospirosis and Q fever in Bos indicus cattle in Cameroon]Serological patterns of brucellosis, leptospirosis and Q fever in Bos indicus cattle in Cameroon

In this presentation we would like to introduce a novel diagnostic tool for Taenia solium cysticercosis in the porcine host. This tool is a rapid, user-friendly lateral flow format assay utilising the HP10 monoclonal antibody. We will describe the production of this assay, its performance as judg...


Doble, L.F.Fèvre, Eric M.Bronsvoort, B.M. de C.Harrison, L.J.S.Parkhouse, R.M.E.Toye, Philip G.[Development of a rapid, user-friendly, diagnostic test for Taenia solium cysticercosis]Development of a rapid, user-friendly, diagnostic test for Taenia solium cysticercosis

The transmission dynamics of infectious disease depends on the frequency and type of contacts between susceptible and infectious individuals or groups. Between-farm contact structures have been defined in several countries, and have been widely used to model disease spread. In this study, we desc...


Glanville, William A. deBronsvoort, B.M. de C.Fèvre, Eric M.[Between farm contacts in western Kenya: Implications for disease transmission]Between farm contacts in western Kenya: Implications for disease transmission

We report on the results of work on three bacterial zoonoses arising as part of a large project dealing with zoonotic infections amongst livestock and the farmers who keep them. Domestic livestock are an important source of zoonotic infections to humans, particularly in rural parts of Africa. Und...


Fèvre, Eric M.Glanville, William A. deDoble, L.F.Cook, Elizabeth A.J.Bronsvoort, B.M. de C.Kariuki, S.Wamae, N.[Epidemiology of bacterial infections in livestock and their human keepers in Western Kenya]Epidemiology of bacterial infections in livestock and their human keepers in Western Kenya

In developing countries, cities are rapidly expanding and urban and peri-urban agriculture (UPA) has an important role in feeding these growing urban populations; however such agriculture also carries public health risks such as zoonotic disease transmission. It is important to assess the role of...


Makita, K.Fèvre, Eric M.Waiswa, C.Bronsvoort, B.M. de C.Eisler, M.C.Welburn, S.C.[Population-dynamics focussed rapid rural mapping and characterization of the peri-urban interface of Kampala, Uganda]Population-dynamics focussed rapid rural mapping and characterization of the peri-urban interface of Kampala, Uganda

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