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Objectives Leptospirosis has been documented in slaughterhouse workers around the world. Risk factors include smoking and drinking at work, and performing tasks such as cleaning offal. This paper examined risk factors for leptospirosis seropositivity in slaughterhouse workers in western Kenya. M...


Cook, Elizabeth A.J.Glanville, William A. deThomas, L.F.Kariuki, S.Bronsvoort, B.M. de C.Fèvre, Eric M.[Risk factors for leptospirosis seropositivity in slaughterhouse workers in western Kenya]Risk factors for leptospirosis seropositivity in slaughterhouse workers in western Kenya

The major histocompatibility complex (MHC) region contains many genes that are key regulators of both innate and adaptive immunity including the polymorphic MHCI and MHCII genes. Consequently, the characterisation of the repertoire of MHC genes is critical to understanding the variation that dete...


Vasoya, D.Law, A.Motta, P.Mingyan YuMuwonge, A.Cook, Elizabeth A.J.Xiaoying LiBryson, K.MacCallam, A.Sitt, T.Toye, Philip G.Bronsvoort, B.M. de C.Watson, MickMorrison, W. IvanConnelley, T.[Rapid identification of bovine MHCI haplotypes in genetically divergent cattle populations using next-generation sequencing]Rapid identification of bovine MHCI haplotypes in genetically divergent cattle populations using next-generation sequencing

The neglected tropical diseases (NTDs) are characterized by their tendency to cluster within groups of people, typically the poorest and most marginalized. Despite this, measures of clustering, such as within-group correlation or between-group heterogeneity, are rarely reported from community-bas...


Glanville, William A. deThomas, Lian F.Cook, Elizabeth A.J.Bronsvoort, B.M. de C.Wardrop, N.Wamae, C.N.Kariuki, S.Fèvre, Eric M.[General contextual effects on neglected tropical disease risk in rural Kenya]General contextual effects on neglected tropical disease risk in rural Kenya

Many individual hosts are infected with multiple parasite species, and this may increase or decrease the pathogenicity of the infections. This phenomenon is termed heterologous reactivity and is potentially an important determinant of both patterns of morbidity and mortality and of the impact of ...


Woolhouse, Mark E.J.Thumbi, S.M.Jennings, A.Chase-Topping, M.Callaby, R.Kiara, Henry K.Oosthuizen, M.C.Mbole-Kariuki, Mary N.Conradie, I.Handel, I.G.Poole, Elizabeth J.Njiiri, E.Collins, N.E.Murray, G.Tapio, M.Auguet, O.T.Weir, W.Morrison, W. IvanKruuk, L.E.B.Bronsvoort, B.M. de C.Hanotte, Olivier H.Coetzer, K.Toye, Philip G.[Co-infections determine patterns of mortality in a population exposed to parasite infection]Co-infections determine patterns of mortality in a population exposed to parasite infection

Tick-borne diseases are a major impediment to improved productivity of livestock in sub-Saharan Africa. Improved control of these diseases would be assisted by detailed epidemiological data. Here we used longitudinal, serological data to determine the patterns of exposure to Theileria parva, Thei...


Kiara, Henry K.Jennings, A.Bronsvoort, B.M. de C.Hande, I.G.Mwangi, S.T.Mbole-Kariuki, Mary N.Wyk, I.C. vanPoole, Elizabeth J.Hanotte, Olivier H.Coetzer, J.A.W.Woolhouse, Mark E.J.Toye, Philip G.[A longitudinal assessment of the serological response to Theileria parva and other tick-borne parasites from birth to one year in a cohort of indigenous calves in western Kenya]A longitudinal assessment of the serological response to Theileria parva and other tick-borne parasites from birth to one year in a cohort of indigenous calves in western Kenya

Parasite burden varies widely between individuals within a population, and can covary with multiple aspects of individual phenotype. Here we investigate the sources of variation in faecal strongyle eggs counts, and its association with body weight and a suite of haematological measures, in a coho...


Callaby, R.Hanotte, Olivier H.Wyk, I.C. vanKiara, Henry K.Toye, Philip G.Mbole-Kariuki, Mary N.Jennings, A.Thumbi, S.M.Coetzer, J.A.W.Bronsvoort, B.M. de C.Knott, S.A.Woolhouse, Mark E.J.Kruuk, L.E.B.[Variation and covariation in strongyle infection in East African shorthorn zebu calves]Variation and covariation in strongyle infection in East African shorthorn zebu calves

Most studies of infectious diseases in East African cattle have concentrated on gastro-intestinal parasites and vector-borne diseases. As a result, relatively little is known about viral diseases, except for those that are clinically symptomatic or which affect international trade such as foot an...


Callaby, R.Toye, Philip G.Jennings, A.Thumbi, S.M.Wyk, I.C. vanHanotte, Olivier H.Mbole-Kariuki, Mary N.Bronsvoort, B.M. de C.Kruuk, L.E.B.Woolhouse, Mark E.J.Kiara, Henry K.[Seroprevalence of respiratory viral pathogens of indigenous calves in western Kenya]Seroprevalence of respiratory viral pathogens of indigenous calves in western Kenya
Scolamacchia, F.Handel, I.G.Fèvre, Eric M.Morgan, K.L.Tanya, V.N.Bronsvoort, B.M. de C.[Serological patterns of brucellosis, leptospirosis and Q fever in Bos indicus cattle in Cameroon]Serological patterns of brucellosis, leptospirosis and Q fever in Bos indicus cattle in Cameroon
Fèvre, Eric M.Bronsvoort, B.M. de C.Hamilton, K.A.Cleaveland, S.[Animal movements and the spread of infectious diseases]Animal movements and the spread of infectious diseases
Bronsvoort, B.M. de C.Wissmann, B. vonFèvre, Eric M.Handel, I.G.Picozzi, K.Welburn, S.C.[No gold standard estimation of the sensitivity and specificity of two molecular diagnostic protocols for Trypanosoma brucei spp. in Western Kenya]No gold standard estimation of the sensitivity and specificity of two molecular diagnostic protocols for Trypanosoma brucei spp. in Western Kenya

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