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Host resistance is the most widely explored strategy for eliminating aflatoxin contamination by Aspergillus flavus. Breeding strategies for developing resistant corn germplasm have been enhanced by the development of new screening tools for field inoculation and for laboratory screening. RFLP ana...


Brown, R.L.Zhi-Yuan, C.Menkir, A.Cleveland, T.E.[Using biotechnology to enhance host resistance to aflatoxin contaminiation of corn]Using biotechnology to enhance host resistance to aflatoxin contaminiation of corn

Aflatoxin contamination caused by the opportunistic pathogen A. flavus is a major concern in maize production prior to harvest and through storage. Previous studies have highlighted the constitutive production of proteins involved in maize kernel resistance against A. flavus’ infection. However, ...


Luo, M.Brown, R.L.Chen, Z.Y.Menkir, A.Yu, J.Bhatnagar, D.[Transcriptional profiles uncover Aspergillus flavus-induced resistance in maize kernels]Transcriptional profiles uncover Aspergillus flavus-induced resistance in maize kernels

Aflatoxin contamination of maize by Aspergillus flavus poses serious potential economic losses in the US and health hazards to humans, particularly in West Africa. The Southern Regional Research Center of the United States Department of Agriculture, Agricultural Research Service (USDA-ARS-SRRC) a...


Menkir, A.Brown, R.L.Bandyopadhyay, RanajitChen, Z.Y.Cleveland, T.E.[A USA Africa collaborative strategy for identifying, characterising and developing maize germplasm with resistance to aflatoxin contamination]A USA Africa collaborative strategy for identifying, characterising and developing maize germplasm with resistance to aflatoxin contamination

Efforts to identify maize germplasm with resistance to Aspergillus flavus infection and subsequent accumulation of aflatoxins were initiated by the US Department of Agriculture, Agricultural Research Service at several locations in the late 1970s and early 1980s. Research units at four locati...


Williams, W.P.Krakowsky, M.D.Scully, B.T.Brown, R.L.Menkir, A.Warburton, M.L.Windham, G.L.[Identifying and developing maize germplasm with resistance to accumulation of aflatoxins]Identifying and developing maize germplasm with resistance to accumulation of aflatoxins

Aspergillus flavus infection of maize and subsequent contamination with carcinogenic aflatoxins poses serious health concerns, especially in developing countries. Maize lines resistant to A. flavus infection have been identified; however, the development of commercially-useful aflatoxin-resistant...


Chen, Z.Brown, R.L.Menkir, A.Cleveland, T.E.[Identification of resistanceassociated proteins in closelyrelated maize lines varying in aflatoxin accumulation]Identification of resistanceassociated proteins in closelyrelated maize lines varying in aflatoxin accumulation

Aflatoxins are carcinogenic secondary metab-olites produced mainly byAspergillus flavusLinkex. Fries, andA. prarasiticusSpeare duringinfection of susceptible crops, such as maize,cottonseed, peanuts and tree nuts. This paper willreview research efforts in identifying afla...


Chen, Z.Y.Brown, R.L.Guo, B.Z.Menkir, A.Cleveland, T.E.[Identifying aflatoxin resistance related proteins/genes through proteomics and RNAi gene silencing]Identifying aflatoxin resistance related proteins/genes through proteomics and RNAi gene silencing

Aflatoxin accumulation in maize (Zea mays L.) kernels is a serious economic and health problem that reduces grain quality and nutritional values and causes death to livestock and humans. Understanding the genetic parameters and heterotic responses of exotic maize inbred lines can facilitate their...


Meseka, S.Williams, W.P.Warburton, M.L.Brown, R.L.Augusto, J.Ortega-Beltran, A.Bandyopadhyay, RanajitMenkir, A.[Heterotic affinity and combining ability of exotic maize inbred lines for resistance to aflatoxin accumulation]Heterotic affinity and combining ability of exotic maize inbred lines for resistance to aflatoxin accumulation

Aflatoxins, produced by the fungus Aspergillus flavus, contaminate maize grain and threaten human food and feed safety. Plant resistance is considered the best strategy for reducing aflatoxin accumulation. Six maize germplasm lines, TZAR101–TZAR106, were released by the International Institute of...


Brown, R.L.Williams, W.P.Windham, G.L.Menkir, A.Chen, Z.Y.[Evaluation of African-bred maize germplasm lines for resistance to aflatoxin accumulation]Evaluation of African-bred maize germplasm lines for resistance to aflatoxin accumulation

Several maize near-isogenic inbred lines were subjected to comparative proteomics to identify kernel proteins associated with resistance. These lines were developed in Nigeria through a joint project between ARS-SRRC and the International Institute of Tropical Agriculture. The goal of this projec...


Brown, R.L.Menkir, A.Bandyopadhyay, RanajitCleveland, T.E.Chen, Z.[Comparative proteomics of nearisogenic maize inbred lines to identify potential aflatoxinresistance markers]Comparative proteomics of nearisogenic maize inbred lines to identify potential aflatoxinresistance markers

Thirty-six inbred lines selected in West and Central Africa for moderate to high resistance to maize ear rot under conditions of severe natural infection were screened for resistance to aflatoxin contamination using the previously established kernel screening assay. Results showed that more than ...


Brown, R.L.Chen, Z.Y.Menkir, A.Cleveland, T.E.Cardwell, K.Kling, J.White, D.G.[Resistance to aflatoxin accumulation in kernels of maize inbreds selected for ear rot resistance in West and Central Africa]Resistance to aflatoxin accumulation in kernels of maize inbreds selected for ear rot resistance in West and Central Africa

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