Theileria parva antigens recognized by cytotoxic T lymphocytes (CTLs) are prime vaccine candidates against East Coast Fever in cattle. A strategy for enhancing induction of parasite-specific T cell responses by increasing recruitment and activation of dendritic cells (DCs) at the immunization sit...
Mwangi, D.M.
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Honda, Y.
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Graham, S.P.
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Pelle, Roger
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Taracha, E.L.N.
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Gachanja, J.
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Nyanjui, J.K.
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Bray, J.
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Palmer, G.H.
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Brown, W.C.
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Mwangi, W.
,
[Treatment of cattle with DNA-encoded Flt3L and GM-CSF prior to immunization with Theileria parva candidate vaccine antigens induces CD4 and CD8 T cell IFN-γ responses but not CTL responses]
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Treatment of cattle with DNA-encoded Flt3L and GM-CSF prior to immunization with Theileria parva candidate vaccine antigens induces CD4 and CD8 T cell IFN-γ responses but not CTL responses
Brown, W.C.
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Shaw, M.K.
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Conrad, P.A.
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Dolan, T.T.
,
[Theileria-parva: Reappearance of schizonts in infected lymphoblastoid cells treated with parvaquone is dependent on interleukin 2-like growth factors]
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Theileria-parva: Reappearance of schizonts in infected lymphoblastoid cells treated with parvaquone is dependent on interleukin 2-like growth factors
Alpha gamma T cells in ruminants can be subdivided in two or more subpopulations on the basis of the expression of surface antigen WC1, which can exist in different isoforms. In this study, 18 monoclonal antibodies (mAbs) submitted to the Third International Workshop that were predicted to react ...
Davis, W.C.
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Brown, W.C.
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Hamilton, M.J.
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Wyatt, C.R.
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Orden, J.A.
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Khalid, A.M.
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Naessens, Jan
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[Analysis of monoclonal antibodies specific for the gamma alpha TcR]
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Analysis of monoclonal antibodies specific for the gamma alpha TcR
Brown, W.C.
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Grab, D.J.
,
[Biological and biochemical characterization of bovine interleukin. 2. Studies with cloned bovine T cells]
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Biological and biochemical characterization of bovine interleukin. 2. Studies with cloned bovine T cells
Monoclonal antibodies potentially specific for antigens expressed or upregulated on activated leukocytes were selected for further analysis from the panel submitted to the third international workshop on ruminant leukocyte antigens. The kinetics of expression of these activation antigens or resti...
Davis, W.C.
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Naessens, Jan
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Brown, W.C.
,
Ellis, J.A.
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Hamilton, M.J.
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Canton, G.H.
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Barbosa, J.J.R.
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Ferens, W.
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Bohach, G.A.
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[Analysis of monoclonal antibodies reactive with molecules upregulated or expressed only on activated lymphocytes]
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Analysis of monoclonal antibodies reactive with molecules upregulated or expressed only on activated lymphocytes
Sugimoto, C.
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Mutharia, L.M.
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Conrad, P.A.
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Dolan, T.T.
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Brown, W.C.
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Doddeeris, B.M.
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Pearson, T.W.
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[Protein changes in bovine lymphoblastoid cells induced by infection with the intracellular parasite Theileria parva]
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Protein changes in bovine lymphoblastoid cells induced by infection with the intracellular parasite Theileria parva
Baldwin, C.L.
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Iams, K.P.
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Brown, W.C.
,
Grab, D.J.
,
[Theileria parva: CD4+ helper and cytotoxic T-cell clones react with a schizont-derived antigen associated with the surface of Theileria parva-infected lymphocytes]
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Theileria parva: CD4+ helper and cytotoxic T-cell clones react with a schizont-derived antigen associated with the surface of Theileria parva-infected lymphocytes
Brown, W.C.
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Sugimoto, C.
,
Grab, D.J.
,
[Theileria parva: Bovine helper T cell clones specific for both infected lymphocytes and schizont membrane antigens]
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Theileria parva: Bovine helper T cell clones specific for both infected lymphocytes and schizont membrane antigens
Grab, D.J.
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Baldwin, C.L.
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Brown, W.C.
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Innes, E.A.
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Lonsdale-Eccles, J.D.
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Verjee, Y.
,
[Immune CD4+ T cells specific for Theileria parva-infected lymphocytes recognize a 24-kilodalton protein]
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Immune CD4+ T cells specific for Theileria parva-infected lymphocytes recognize a 24-kilodalton protein
Morrison, W. Ivan
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Goddeeris, M.
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Brown, W.C.
,
Baldwin, C.L.
,
Teale, A.J.
,
[Theileria parva in cattle: Characterization of infected lymphocytes and the immune responses they provoke]
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Theileria parva in cattle: Characterization of infected lymphocytes and the immune responses they provoke