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Svitek, NicholasHansen, A.M.Steinaa, LucillaSaya, R.Awino, A.Nielsen, MortenBuus, SorenNene, Vishvanath[Immunoinformatics and MHC-Tetramers, revolutionary technologies for vaccine development]Immunoinformatics and MHC-Tetramers, revolutionary technologies for vaccine development
Svitek, NicholasSteinaa, LucillaSaya, R.Awino, EliasNielsen, MortenBuus, SorenNene, Vishvanath[The quest for the needle (antigen) in the haystack (pathogen): Immunoinformatics to the rescue]The quest for the needle (antigen) in the haystack (pathogen): Immunoinformatics to the rescue

T cell responses contribute to immunity against many intracellular infections. There is, for example, strong evidence that major histocompatibility complex (MHC) class I-restricted cytotoxic T lymphocytes (CTLs) play an essential role in mediating immunity to East Coast fever (ECF), a fatal lymph...


Nene, VishvanathSvitek, NicholasToye, Philip G.Golde, W.T.Barlow, J.Buus, SorenNielsen, Morten[Designing bovine T cell vaccines via reverse immunology]Designing bovine T cell vaccines via reverse immunology

Peptide-major histocompatibility complex (p-MHC) class I tetramer complexes have facilitated the early detection and functional characterisation of epitope specific CD8+ cytotoxic T lymphocytes (CTL). Here, we report on the generation of seven recombinant bovine leukocyte antigens (BoLA) and reco...


Svitek, NicholasHansen, A.M.Steinaa, LucillaSaya, R.Awino, EliasNielsen, MortenBuus, SorenNene, Vishvanath[Use of “one-pot, mix-and-read” peptide-MHC class I tetramers and predictive algorithms to improve detection of cytotoxic T lymphocyte responses in cattle]Use of “one-pot, mix-and-read” peptide-MHC class I tetramers and predictive algorithms to improve detection of cytotoxic T lymphocyte responses in cattle

Steinaa, LucillaHenson, Sonal P.Buus, SorenStryhn, AnnetteNielsen, MortenSvitek, NicholasOnzere, Cynthia K.Nyambego, Edwina B.Ndambuki, Gideon M.Bishop, Richard P.[Sequencing swine leucocyte alleles for vaccine development]Sequencing swine leucocyte alleles for vaccine development

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