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Article 2018-05

Somatotropic axis dysfunction in non-alcoholic fatty liver disease: Beneficial hepatic and systemic effects of hormone supplementation

Autor: Cabrera, D. Cabello-Verrugio, C. Solís, N. Martín, D.S. Cofré, C. Pizarro, M. Arab, J.P. Abrigo, J. Campos, F. Irigoyen, B. Carrasco-Avino, G. Bezares, K. Riquelme, V. Riquelme, A. Arrese, M. Barrera, F.

Background: Somatotropic axis dysfunction associated with non-alcoholic fatty liver disease (NAFLD) has potential multisystemic detrimental effects. Here, we analysed the effects of growth hormone (GH) and insulin-like growth factor-1 (IGF-1) supplementation on liver histology, adipokine profile ...

Enlace original: http://repositorio.unab.cl/xmlui/handle/ria/8891

Repositorio Universidad Andrés Bello

Fatty liver

Growth hormone

IGF-1

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Cabrera, D. , Cabello-Verrugio, C. , Solís, N. , Martín, D.S. , Cofré, C. , Pizarro, M. , Arab, J.P. , Abrigo, J. , Campos, F. , Irigoyen, B. , Carrasco-Avino, G. , Bezares, K. , Riquelme, V. , Riquelme, A. , Arrese, M. , Barrera, F. , [Somatotropic axis dysfunction in non-alcoholic fatty liver disease: Beneficial hepatic and systemic effects of hormone supplementation] , Somatotropic axis dysfunction in non-alcoholic fatty liver disease: Beneficial hepatic and systemic effects of hormone supplementation

Article 2018-04

Combined therapies for Duchenne muscular dystrophy to optimize treatment efficacy

Autor: Cordova, G. Negroni, E. Cabello-Verrugio, C. Mouly, V. Trollet, C.

Duchene Muscular Dystrophy (DMD) is the most frequent muscular dystrophy and one of the most severe due to the absence of the dystrophin protein. Typical pathological features include muscle weakness, muscle wasting, degeneration, and inflammation. At advanced stages DMD muscles present exacerbat...

Enlace original: http://repositorio.unab.cl/xmlui/handle/ria/8278

Repositorio Universidad Andrés Bello

Atrophy

Cell therapy

Duchenne muscular dystrophy

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Cordova, G. , Negroni, E. , Cabello-Verrugio, C. , Mouly, V. , Trollet, C. , [Combined therapies for Duchenne muscular dystrophy to optimize treatment efficacy] , Combined therapies for Duchenne muscular dystrophy to optimize treatment efficacy

Article 2016-04

Angiotensin-(1-7) attenuates disuse skeletal muscle atrophy in mice via its receptor, Mas

Autor: Morales, M.G. Abrigo, J. Acuna, M.J. Santos, R.A. Bader, M. Brandan, E. Simon, F. Olguin, H. Cabrera, D. Cabello-Verrugio, C.

Immobilization is a form of disuse characterized by a loss of strength and muscle mass. Among the main features are decreased IGF-1/Akt signalling and increased ubiquitin-proteasome pathway signalling, which induce greater myosin heavy chain degradation. Activation of the classical renin-angioten...

Enlace original: http://repositorio.unab.cl/xmlui/handle/ria/3994

Repositorio Universidad Andrés Bello

Angiotensin-(1-7)

Atrophy

Disuse

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Morales, M.G. , Abrigo, J. , Acuna, M.J. , Santos, R.A. , Bader, M. , Brandan, E. , Simon, F. , Olguin, H. , Cabrera, D. , Cabello-Verrugio, C. , [Angiotensin-(1-7) attenuates disuse skeletal muscle atrophy in mice via its receptor, Mas] , Angiotensin-(1-7) attenuates disuse skeletal muscle atrophy in mice via its receptor, Mas

Article 2017-06

Andrographolide Ameliorates Inflammation and Fibrogenesis and Attenuates Inflammasome Activation in Experimental Non-Alcoholic Steatohepatitis

Autor: Cabrera, D. Wree, A. Povero, D. Solís, N. Hernandez, A. Pizarro, M. Moshage, H. Torres, J. Feldstein, A.E. Cabello-Verrugio, C. Brandan, E. Barrera, F. Arab, J.P. Arrese, M.

Therapy for nonalcoholic steatohepatitis (NASH) is limited. Andrographolide (ANDRO), a botanical compound, has a potent anti-inflammatory activity due to its ability to inhibit NF-κB. ANDRO has been also shown to inhibit the NLRP3 inflammasome, a relevant pathway in NASH. Our aim was to evaluate ...

Enlace original: http://repositorio.unab.cl/xmlui/handle/ria/4736

Repositorio Universidad Andrés Bello

FATTY LIVER-DISEASE

NF-KAPPA-B

NLRP3 INFLAMMASOME

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Cabrera, D. , Wree, A. , Povero, D. , Solís, N. , Hernandez, A. , Pizarro, M. , Moshage, H. , Torres, J. , Feldstein, A.E. , Cabello-Verrugio, C. , Brandan, E. , Barrera, F. , Arab, J.P. , Arrese, M. , [Andrographolide Ameliorates Inflammation and Fibrogenesis and Attenuates Inflammasome Activation in Experimental Non-Alcoholic Steatohepatitis] , Andrographolide Ameliorates Inflammation and Fibrogenesis and Attenuates Inflammasome Activation in Experimental Non-Alcoholic Steatohepatitis

Article 2018

Oxidative stress in disease and aging: Mechanisms and therapies 2018

Autor: Cabello-Verrugio, C. Vilos, C. Rodrigues-Diez, R. Estrada, L.

Enlace original: http://repositorio.unab.cl/xmlui/handle/ria/11391

Repositorio Universidad Andrés Bello

Aging

Antioxidants

Cardiomyopathies

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Cabello-Verrugio, C. , Vilos, C. , Rodrigues-Diez, R. , Estrada, L. , [Oxidative stress in disease and aging: Mechanisms and therapies 2018] , Oxidative stress in disease and aging: Mechanisms and therapies 2018

Article 2018-06

Gestational hypothyroxinemia affects its offspring with a reduced suppressive capacity impairing the outcome of the experimental autoimmune encephalomyelitis

Autor: Haensgen, H. Albornoz, E. Opazo, M.C. Bugueño, K. Jara Fernández, E.L. Binzberger, R. Rivero-Castillo, T. Venegas Salas, L.F. Simon, F. Cabello-Verrugio, C. Elorza, A.A. Kalergis, A.M. Bueno, S.M. Riedel, C.A.

Hypothyroxinemia (Hpx) is a thyroid hormone deficiency (THD) condition highly frequent during pregnancy, which although asymptomatic for the mother, it can impair the cognitive function of the offspring. Previous studies have shown that maternal hypothyroidism increases the severity of experiment...

Enlace original: http://repositorio.unab.cl/xmlui/handle/ria/8966

Repositorio Universidad Andrés Bello

Experimental autoimmune encephalomyelitis

Hypothyroxinemia

Multiple sclerosis

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Haensgen, H. , Albornoz, E. , Opazo, M.C. , Bugueño, K. , Jara Fernández, E.L. , Binzberger, R. , Rivero-Castillo, T. , Venegas Salas, L.F. , Simon, F. , Cabello-Verrugio, C. , Elorza, A.A. , Kalergis, A.M. , Bueno, S.M. , Riedel, C.A. , [Gestational hypothyroxinemia affects its offspring with a reduced suppressive capacity impairing the outcome of the experimental autoimmune encephalomyelitis] , Gestational hypothyroxinemia affects its offspring with a reduced suppressive capacity impairing the outcome of the experimental autoimmune encephalomyelitis

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Resultados de búsqueda

Somatotropic axis dysfunction in non-alcoholic fatty liver disease: Beneficial hepatic and systemic effects of hormone supplementation

[Cabrera_D_Somatotropic_Axis_Dysfunction.pdf]

Combined therapies for Duchenne muscular dystrophy to optimize treatment efficacy

[Cordova_Combined_Therapies.pdf]

Angiotensin-(1-7) attenuates disuse skeletal muscle atrophy in mice via its receptor, Mas

[Morales_M_Angiotensin.pdf]

Andrographolide Ameliorates Inflammation and Fibrogenesis and Attenuates Inflammasome Activation in Experimental Non-Alcoholic Steatohepatitis

[Castro-Nallar_Draft_Genome_Sequences.pdf]

Oxidative stress in disease and aging: Mechanisms and therapies 2018

[Cabello-Verrugio_Oxidative_Stress.pdf]

Gestational hypothyroxinemia affects its offspring with a reduced suppressive capacity impairing the outcome of the experimental autoimmune encephalomyelitis

[Haensgen_Gestational.pdf]