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Article 2018-07

Autor: Campanini-Salinas, J. Andrades-Lagos, J. Gonzalez Rocha, G. Choquesillo-Lazarte, D. Bollo Dragnic, S. Faúndez, M. Alarcón, P. Silva, F. Vidal, R. Salas-Huenuleo, E. Kogan, M. Mella, J. Recabarren Gajardo, G. Vásquez-Velásquez, D.

A rapid emergence of resistant bacteria is occurring worldwide, endangering the efficacy of antibiotics and reducing the therapeutic arsenal available for treatment of infectious diseases. In the present study, we developed a new class of compounds with antibacterial activity obtained by a simple...

Enlace original: http://repositorio.unab.cl/xmlui/handle/ria/11461

Repositorio Universidad Andrés Bello
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Campanini-Salinas, J. ,  Andrades-Lagos, J. ,  Gonzalez Rocha, G. ,  Choquesillo-Lazarte, D. ,  Bollo Dragnic, S. ,  Faúndez, M. ,  Alarcón, P. ,  Silva, F. ,  Vidal, R. ,  Salas-Huenuleo, E. ,  Kogan, M. ,  Mella, J. ,  Recabarren Gajardo, G. ,  Vásquez-Velásquez, D. ,  [A New Kind of Quinonic-Antibiotic Useful Against Multidrug-Resistant S. aureus and E. faecium Infections] ,  A New Kind of Quinonic-Antibiotic Useful Against Multidrug-Resistant S. aureus and E. faecium Infections
Article 2018

Autor: Lorca, M. Morales-Verdejo, C. Vásquez-Velásquez, D. Andrades-Lagos, J. Campanini-Salinas, J. Soto-Delgado, J. Recabarren-Gajardo, G. Mella, J.

The wide tissue distribution of the adrenergic β3 receptor makes it a potential target for the treatment of multiple pathologies such as diabetes, obesity, depression, overactive bladder (OAB), and cancer. Currently, there is only one drug on the market, mirabegron, approved for the treatment of ...

Enlace original: http://repositorio.unab.cl/xmlui/handle/ria/8959

Repositorio Universidad Andrés Bello
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Lorca, M. ,  Morales-Verdejo, C. ,  Vásquez-Velásquez, D. ,  Andrades-Lagos, J. ,  Campanini-Salinas, J. ,  Soto-Delgado, J. ,  Recabarren-Gajardo, G. ,  Mella, J. ,  [Structure-activity relationships based on 3D-QSAR CoMFA/CoMSIA and design of aryloxypropanol-amine agonists with selectivity for the human β3-adrenergic receptor and anti-obesity and anti-diabetic profiles] ,  Structure-activity relationships based on 3D-QSAR CoMFA/CoMSIA and design of aryloxypropanol-amine agonists with selectivity for the human β3-adrenergic receptor and anti-obesity and anti-diabetic profiles

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