Cattle from 50 farms in Mukono County, Uganda, were monitored for trypanosomes every second month over an 18-month period (1995–1996) by mini-anion exchange chromatography and haematocrit centrifugation techniques. Eighteen trypanosome isolates collected from cattle during this period were charac...
Olila, D.
,
McDermott, John J.
,
Eisler, M.C.
,
Mitema, E.S.
,
Patzelt, R.J.
,
Clausen, P.H.
,
Poetzsch, C.J.
,
Zessin, K.H.
,
Mehlitz, D.
,
Peregrine, A.S.
,
[Drug sensitivity of trypanosome populations from cattle in a peri-urban dairy production system in Uganda]
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Drug sensitivity of trypanosome populations from cattle in a peri-urban dairy production system in Uganda
Barry, A.M.
,
Vial, Leigh K.
,
Diallo, A.
,
Diallo, B.
,
Diall, O.
,
Manstermann, S.
,
Randolph, Thomas F.
,
Clausen, P.H.
,
[Situation de la trypanosomose et de la résistance aux trypanocides dans les élevages de bovins Ndama de la zone cotonnière de Haute Guinée (Guinée-Conakry)]
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Situation de la trypanosomose et de la résistance aux trypanocides dans les élevages de bovins Ndama de la zone cotonnière de Haute Guinée (Guinée-Conakry)
Trypanocidal drugs are the most commonly purchased and used livestock input by resource-poor farmers in sub-Saharan Africa. The effective use of trypanocidal drugs by smallholder farmers is threatened by the development of widespread resistance. This is a particular concern for smallholder crop-l...
Clausen, P.H.
,
Bauer, B.
,
Zessin, K.H.
,
Diall, O.
,
Bocoum, Z.
,
Sidibe, I.
,
Affognon, Hippolyte D.
,
Waibel, H.
,
Grace, Delia
,
Randolph, Thomas F.
,
[Preventing and containing trypanocide resistance in the cotton zone of West Africa]
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Preventing and containing trypanocide resistance in the cotton zone of West Africa
This study assessed the degree of isometamidium resistance of trypanosomes infecting cattle in the upper Didessa valley of western Ethiopia. An initial prevalence study was conducted to identify sites with a high risk of trypanosmosis in cattle. The trypanosome prevalence varied widely, with t...
Tewelde, N.
,
Abebe, G.
,
Eisler, M.C.
,
McDermott, John J.
,
Greiner, M.
,
Afework, Y.
,
Kyule, M.
,
Munstermann, S.
,
Zessin, K.H.
,
Clausen, P.H.
,
[Application of field methods to assess isometamidium resistance of trypanosomes in cattle in western Ethiopia]
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Application of field methods to assess isometamidium resistance of trypanosomes in cattle in western Ethiopia
Resistance to the drugs used to control African animal trypanosomosis is increasingly recognised as a constraint to livestock production in sub-Saharan Africa. The most commonly used tests for detection of trypanocidal drug resistance are tests using mice or ruminants, but these suffer from lack ...
Eisler, M.C.
,
Brandt, J.
,
Bauer, B.
,
Clausen, P.H.
,
Delespaux, V.
,
Holmes, P.H.
,
Ilemobade, A.
,
Machila, N.
,
Mbwambo, H.
,
McDermott, John J.
,
Mehlitz, D.
,
Murilla, G.
,
Ndung'u, J.M.
,
Peregrine, A.S.
,
Sidibe, I.
,
Sinyangwe, L.
,
Geerts, S.
,
[Standardised tests in mice and cattle for the detection of drug resistance in tsetse-transmitted trypanosomes of African domestic cattle]
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Standardised tests in mice and cattle for the detection of drug resistance in tsetse-transmitted trypanosomes of African domestic cattle
Drug resistant trypanosome infections in livestock have been Reported from 13 sub-Saharan countries so far, in eight of which multiple resistance occurs. Since new trypanocides are unlikely to appear on the market in the near future, information about the occurrence, extent and impact of drug res...
Gall, Y.
,
Woitag, J.
,
Bauer, B.
,
Sidibe, I.
,
McDermott, John J.
,
Eisler, M.C.
,
Mehlitz, D.
,
Clausen, P.H.
,
[Detection of trypanocide failure in cattle: Diagnostic potential of PCR compared to parasitological methods]
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Detection of trypanocide failure in cattle: Diagnostic potential of PCR compared to parasitological methods
Trypanocidal drugs are the most widely applied method of trypanosomosis control in Africa and the only control method in Latin America and Asia . Treatment recommendations and strategies for chemotherapeutic control of trypanosomosis depends on information of trypanosomosis risk and the prevalenc...
Eisler, M.C.
,
McDermott, John J.
,
Mdachi, R.
,
Murilla, G.
,
Sinyangwe, L.
,
Mubanga, J.
,
Machila, N.
,
Mbwambo, H.
,
Coleman, P.G.
,
Clausen, P.H.
,
Bauer, B.
,
Sidibe, I.
,
Geerts, S.
,
Holmes, P.H.
,
Peregrine, A.S.
,
[Rapid method for the assessment of trypanocidal drug resistance in the field]
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Rapid method for the assessment of trypanocidal drug resistance in the field
Diall, O.
,
Randolph, Thomas F.
,
Clausen, P.H.
,
Waibel, H.
,
Sidibe, I.
,
Schoenefeld, A.
,
Boye, D.
,
Bocoum, Z.
,
Sangare, M.
,
[Detection and control of trypanocide resistance: achievements of the ILRI/BMZ project in the cotton zone of West Africa]
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Detection and control of trypanocide resistance: achievements of the ILRI/BMZ project in the cotton zone of West Africa
To investigate the importance of trypanosomosis, resistance to trypanocidal drugs and the potential impact of integrated control measures on these factors, a 3-phase study was initiated. The first phase was a cross-sectional study in which tsetse apparent density, cattle trypanosome prevalence, t...
McDermott, John J.
,
Sidibe, I.
,
Bauer, B.
,
Diarra, B.
,
Clausen, P.H.
,
Woitay, T.
,
Ouédraogo, T.
,
Kamuanga, M.
,
Peregrine, A.S.
,
Eisler, M.C.
,
Mehlitz, D.
,
[Field studies on the Development and impact of drug resistant animal trypanosomes in market oriented production systems in the Southern Guinean zone of West Africa]
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Field studies on the Development and impact of drug resistant animal trypanosomes in market oriented production systems in the Southern Guinean zone of West Africa