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Contreras Saavedra, Osvaldo IsaíasOlguín Marín, Hugo CésarBrandan, EnriqueRebolledo López, Daniela VictoriaOyarzún, Juan Esteban[Connective tissue cells expressing fibro/adipogenic progenitor markers increase under chronic damage : relevance in fibroblast-myofibroblast differentiation and skeletal muscle fibrosis.]Connective tissue cells expressing fibro/adipogenic progenitor markers increase under chronic damage : relevance in fibroblast-myofibroblast differentiation and skeletal muscle fibrosis.

Contreras Saavedra, Osvaldo IsaíasSoliman, HeshamTheret, MarineRossi, Fabio M. V.Brandan, Enrique[TGF-β-driven downregulation of the transcription factor TCF7L2 affects Wnt/β-catenin signaling in PDGFRα+ fibroblasts]TGF-β-driven downregulation of the transcription factor TCF7L2 affects Wnt/β-catenin signaling in PDGFRα+ fibroblasts

Contreras Saavedra, Osvaldo IsaíasCruz-Soca, MeilynTheret, MarineSoliman, HeshamWei Tung, LinGroppa, ElenaRossi, Fabio M.Brandan, Enrique[Cross-talk between TGF-β and PDGFRα signaling pathways regulates the fate of stromal fibro–adipogenic progenitors]Cross-talk between TGF-β and PDGFRα signaling pathways regulates the fate of stromal fibro–adipogenic progenitors
Contreras Saavedra, Osvaldo IsaíasRebolledo, D.Oyarzún, J.Olguín Marín, Hugo CésarBrandan, Enrique[Connective tissue cells expressing fibro/adipogenic progenitor markers increase under chronic damage: relevance in fibroblast-myofibroblast differentiation and skeletal muscle fibrosismuscle fibrosis]Connective tissue cells expressing fibro/adipogenic progenitor markers increase under chronic damage: relevance in fibroblast-myofibroblast differentiation and skeletal muscle fibrosismuscle fibrosis
González Vicente, GilbertoBaudrand, R.Sepúlveda, M. F.Vucetich, N.Guarda, F. J.Villanueva, P.Contreras Saavedra, Osvaldo IsaíasVilla, A.Salech, F.Toro, L.Florenzano, P.[Tumor induced-osteomalacia: experience from a Southamerican academic center]Tumor induced-osteomalacia: experience from a Southamerican academic center

Fibrosis, the dysregulated accumulation of connective tissue (CT), is a hallmark of multiple pathologies where inflammation is not fully resolved. The main components of the CT are the extracellular matrix (ECM) and its tissue-resident mesenchymal stromal cells (MSCs), which actively produce and ...


Contreras Saavedra, Osvaldo Isaías[Role of mesenchymal fibro/adipogenic progenitors in homeostasis and disease : from signaling to fibrosis]Role of mesenchymal fibro/adipogenic progenitors in homeostasis and disease : from signaling to fibrosis

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