Wildebeest-associated malignant catarrhal fever (WA-MCF), a fatal disease of cattle caused by alcelaphine herpesvirus 1 (AlHV-1), is one of the most important seasonal diseases of cattle in wildebeest endemic areas, with annual incidence reaching 10%. Here we report efficacy of over 80% for a vac...
Cook, Elizabeth A.J.
,
Russell, George
,
Grant, Dawn
,
Mutisya, Christine N.
,
Omoto, Lazarus
,
Dobson, Elizabeth
,
Lankester, Felix
,
Nene, Vishvanath
,
[A randomised vaccine field trial in Kenya demonstrates protection against wildebeest-associated malignant catarrhal fever in cattle]
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A randomised vaccine field trial in Kenya demonstrates protection against wildebeest-associated malignant catarrhal fever in cattle
Taenia spp. infections, particularly cysticercosis, cause considerable health impacts in endemic countries. Despite previous evidence of spatial clustering in cysticercosis and the role of environmental factors (e.g. temperature and humidity) in the survival of eggs, little research has explored ...
Wardrop, N.A.
,
Thomas, L.F.
,
Atkinson, P.M.
,
Glanville, William A. de
,
Cook, Elizabeth A.J.
,
Wamae, C.N.
,
Gabriël, S.
,
Dorny, P.
,
Harrison, L.J.S.
,
Fèvre, Eric M.
,
[The influence of socio-economic, behavioural and environmental factors on Taenia spp. transmission in western Kenya: Evidence from a cross-sectional survey in humans and pigs]
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The influence of socio-economic, behavioural and environmental factors on Taenia spp. transmission in western Kenya: Evidence from a cross-sectional survey in humans and pigs
Evidence suggests that the intracellular bacterial pathogen Coxiella burnetii (which causes Q fever) is widespread, with a near global distribution. While there has been increasing attention to Q fever epidemiology in high-income settings, a recent systematic review highlighted significant gaps i...
Wardrop, N.A.
,
Thomas, L.F.
,
Cook, Elizabeth A.J.
,
Glanville, William A. de
,
Atkinson, P.M.
,
Wamae, C.N.
,
Fèvre, Eric M.
,
[The sero-epidemiology of Coxiella burnetii in humans and cattle, western Kenya: Evidence from a cross-sectional study]
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The sero-epidemiology of Coxiella burnetii in humans and cattle, western Kenya: Evidence from a cross-sectional study
Three hundred forty-three pigs slaughtered and marketed in western Kenya were subjected to lingual examination and HP10 Ag-ELISA for the serological detection of Taenia solium antigen. When estimates were adjusted for the sensitivity and specificity of the diagnostic assays, prevalence of T. soli...
Thomas, L.F.
,
Harrison, L.J.S.
,
Toye, Philip G.
,
Glanville, William A. de
,
Cook, Elizabeth A.J.
,
Wamae, C.N.
,
Fèvre, Eric M.
,
[Prevalence of Taenia solium cysticercosis in pigs entering the food chain in western Kenya]
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Prevalence of Taenia solium cysticercosis in pigs entering the food chain in western Kenya
In this cross-sectional seroepidemiological study we sought to examine the evidence for circulation of Rift Valley
fever virus (RVFV) among herders in Madagascar and Kenya. From July 2010 to June 2012, we enrolled 459
herders and 98 controls (without ruminant exposures) and studied their sera (im...
Gray, G.C.
,
Anderson, B.D.
,
LaBeaud, D.
,
Heraud, J.M.
,
Fèvre, Eric M.
,
Andriamandimby, S.F.
,
Cook, Elizabeth A.J.
,
Dahir, S.
,
Glanville, William A. de
,
Heil, G.L.
,
Khan, S.U.
,
Muiruri, S.
,
Olive, M.M.
,
Thomas, L.F.
,
Merrill, H.R.
,
Merrill, M.L.M.
,
Richt, J.A.
,
[Seroepidemiological study of interepidemic Rift Valley fever virus infection among persons with intense ruminant exposure in Madagascar and Kenya]
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Seroepidemiological study of interepidemic Rift Valley fever virus infection among persons with intense ruminant exposure in Madagascar and Kenya
The tapeworm Taenia solium is the parasite responsible for neurocysticercosis, a neglected tropical disease of public health importance, thought to cause approximately 1/3 of epilepsy cases across endemic regions. The consumption of undercooked infected pork perpetuates the parasite’s life-cycle ...
Thomas, L.F.
,
Glanville, William A. de
,
Cook, Elizabeth A.J.
,
Bronsvoort, B.M. de C.
,
Handel, I.
,
Wamae, C.N.
,
Kariuki, S.
,
Fèvre, Eric M.
,
[Modelling the risk of Taenia solium exposure from pork produced in western Kenya]
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Modelling the risk of Taenia solium exposure from pork produced in western Kenya
Orono, S.A.
,
Gitao, G.C.
,
Mpatswenumugabo, J.P.
,
Chepkwony, M.
,
Mutisya, Christine N.
,
Okoth, Edward A.
,
Bronsvoort, B.M.C. de
,
Russell, G.C.
,
Nene, Vishvanath
,
Cook, Elizabeth A.J.
,
[Field validation of clinical and laboratory diagnosis of wildebeest associated malignant catarrhal fever in cattle]
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Field validation of clinical and laboratory diagnosis of wildebeest associated malignant catarrhal fever in cattle
The importance of household socio-economic position (SEP) in shaping individual infectious disease risk is increasingly recognised, particularly in low income settings. However, few studies have measured the extent to which this association is consistent for the range of pathogens that are typica...
Glanville, William A. de
,
Thomas, L.F.
,
Cook, Elizabeth A.J.
,
Bronsvoort, B.M. de C.
,
Wamae, N.C.
,
Kariuki, S.
,
Fèvre, Eric M.
,
[Household socio-economic position and individual infectious disease risk in rural Kenya]
,
Household socio-economic position and individual infectious disease risk in rural Kenya
Patel, Ekta
,
Mwaura, Stephen
,
Giulio, Giuseppe di
,
Cook, Elizabeth A.J.
,
Lynen, Godelieve
,
Toye, Philip G.
,
[Infection and treatment method (ITM) vaccine against East Coast fever: Reducing the number of doses per straw for use in smallholder dairy herds by thawing, diluting and refreezing already packaged vaccine]
,
Infection and treatment method (ITM) vaccine against East Coast fever: Reducing the number of doses per straw for use in smallholder dairy herds by thawing, diluting and refreezing already packaged vaccine
Background: African swine fever (ASF), caused by African swine fever virus (ASFV), is a severe haemorrhagic disease
of pigs, outbreaks of which can have a devastating impact upon commercial and small-holder pig production. Pig
production in western Kenya is characterised by low-input, free-range ...
Thomas, L.F.
,
Bishop, Richard P.
,
Onzere, Cynthia K.
,
Mcintosh, M.T.
,
Lemire, K.A.
,
Glanville, William A. de
,
Cook, Elizabeth A.J.
,
Fèvre, Eric M.
,
[Evidence for the presence of African swine fever virus in an endemic region of Western Kenya in the absence of any reported outbreak]
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Evidence for the presence of African swine fever virus in an endemic region of Western Kenya in the absence of any reported outbreak