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Influenza D virus has been identified in America, Europe, and Asia. We detected influenza D virus antibodies in cattle and small ruminants from North (Morocco) and West (Togo and Benin) Africa. Dromedary camels in Kenya harbored influenza C or D virus antibodies, indicating a potential new host f...


Salem, E.Cook, Elizabeth A.J.Lbacha, H.A.Oliva, J.Awoume, F.Aplogan, G.L.Hymann, E.C.Muloi, D.Deem, S.L.Alali, S.Zouagui, Z.Fèvre, Eric M.Meyer, G.Ducatez, M.F.[Serologic evidence for influenza C and D virus among ruminants and camelids, Africa, 1991–2015]Serologic evidence for influenza C and D virus among ruminants and camelids, Africa, 1991–2015

Background Leptospirosis is a neglected zoonosis of public health importance transmitted through contact with contaminated soil, water or urine of infected animals. In pigs the disease is characterized by abortion, still births and weak piglets. A cross-sectional study was conducted in May to Jul...


Ngugi, J.N.Fèvre, Eric M.Mgode, G.F.Obonyo, M.Mhamphi, G.G.Otieno, C.A.Cook, Elizabeth A.J.[Seroprevalence and associated risk factors of leptospirosis in slaughter pigs: A neglected public health risk, western Kenya]Seroprevalence and associated risk factors of leptospirosis in slaughter pigs: A neglected public health risk, western Kenya

Background The neglected zoonotic diseases (NZD) are an understudied group that are a major cause of illness throughout the developing world. In general, little is known about the prevalence and burden of NZDs in affected communities, particularly in relation to other infectious diseases with whi...


Fèvre, Eric M.Glanville, William A. deThomas, L.F.Cook, Elizabeth A.J.Kariuki, S.Wamae, C.N.[An integrated study of human and animal infectious disease in the Lake Victoria crescent small-holder crop-livestock production system, Kenya]An integrated study of human and animal infectious disease in the Lake Victoria crescent small-holder crop-livestock production system, Kenya

Eimeriosis is caused by a protozoan infection affecting most domestic animal species. Outbreaks in cattle are associated with various environmental factors in temperate climates but limited work has been done in tropical settings. The objective of this work was to determine the prevalence and env...


Makau, D.N.Gitau, G.K.Muchemi, G.K.Thomas, L.F.Cook, Elizabeth A.J.Wardrop, N.A.Fèvre, Eric M.Glanville, William A. de[Environmental predictors of bovine Eimeria infection in western Kenya]Environmental predictors of bovine Eimeria infection in western Kenya

Objectives Leptospirosis has been documented in slaughterhouse workers around the world. Risk factors include smoking and drinking at work, and performing tasks such as cleaning offal. This paper examined risk factors for leptospirosis seropositivity in slaughterhouse workers in western Kenya. M...


Cook, Elizabeth A.J.Glanville, William A. deThomas, L.F.Kariuki, S.Bronsvoort, B.M. de C.Fèvre, Eric M.[Risk factors for leptospirosis seropositivity in slaughterhouse workers in western Kenya]Risk factors for leptospirosis seropositivity in slaughterhouse workers in western Kenya

The major histocompatibility complex (MHC) region contains many genes that are key regulators of both innate and adaptive immunity including the polymorphic MHCI and MHCII genes. Consequently, the characterisation of the repertoire of MHC genes is critical to understanding the variation that dete...


Vasoya, D.Law, A.Motta, P.Mingyan YuMuwonge, A.Cook, Elizabeth A.J.Xiaoying LiBryson, K.MacCallam, A.Sitt, T.Toye, Philip G.Bronsvoort, B.M. de C.Watson, MickMorrison, W. IvanConnelley, T.[Rapid identification of bovine MHCI haplotypes in genetically divergent cattle populations using next-generation sequencing]Rapid identification of bovine MHCI haplotypes in genetically divergent cattle populations using next-generation sequencing

The neglected tropical diseases (NTDs) are characterized by their tendency to cluster within groups of people, typically the poorest and most marginalized. Despite this, measures of clustering, such as within-group correlation or between-group heterogeneity, are rarely reported from community-bas...


Glanville, William A. deThomas, Lian F.Cook, Elizabeth A.J.Bronsvoort, B.M. de C.Wardrop, N.Wamae, C.N.Kariuki, S.Fèvre, Eric M.[General contextual effects on neglected tropical disease risk in rural Kenya]General contextual effects on neglected tropical disease risk in rural Kenya

Wildebeest-associated malignant catarrhal fever (WA-MCF), a fatal disease of cattle caused by alcelaphine herpesvirus 1 (AlHV-1), is one of the most important seasonal diseases of cattle in wildebeest endemic areas, with annual incidence reaching 10%. Here we report efficacy of over 80% for a vac...


Cook, Elizabeth A.J.Russell, GeorgeGrant, DawnMutisya, Christine N.Omoto, LazarusDobson, ElizabethLankester, FelixNene, Vishvanath[A randomised vaccine field trial in Kenya demonstrates protection against wildebeest-associated malignant catarrhal fever in cattle]A randomised vaccine field trial in Kenya demonstrates protection against wildebeest-associated malignant catarrhal fever in cattle

Evidence suggests that the intracellular bacterial pathogen Coxiella burnetii (which causes Q fever) is widespread, with a near global distribution. While there has been increasing attention to Q fever epidemiology in high-income settings, a recent systematic review highlighted significant gaps i...


Wardrop, N.A.Thomas, L.F.Cook, Elizabeth A.J.Glanville, William A. deAtkinson, P.M.Wamae, C.N.Fèvre, Eric M.[The sero-epidemiology of Coxiella burnetii in humans and cattle, western Kenya: Evidence from a cross-sectional study]The sero-epidemiology of Coxiella burnetii in humans and cattle, western Kenya: Evidence from a cross-sectional study

Three hundred forty-three pigs slaughtered and marketed in western Kenya were subjected to lingual examination and HP10 Ag-ELISA for the serological detection of Taenia solium antigen. When estimates were adjusted for the sensitivity and specificity of the diagnostic assays, prevalence of T. soli...


Thomas, L.F.Harrison, L.J.S.Toye, Philip G.Glanville, William A. deCook, Elizabeth A.J.Wamae, C.N.Fèvre, Eric M.[Prevalence of Taenia solium cysticercosis in pigs entering the food chain in western Kenya]Prevalence of Taenia solium cysticercosis in pigs entering the food chain in western Kenya

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