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Tomato crops can be affected by several infectious diseases produced by bacteria, fungi, and oomycetes. Four phytopathogens are of special concern because of the major economic losses they generate worldwide in tomato production; Clavibacter michiganensis subsp. michiganensis and Pseudomonas syri...


Montenegro, I.Madrid, A.Cuellar, M.Seeger, M.Alfaro, J.F.Besoain, X.Martínez, J.P.Ramirez, I.Olguín, Y.Valenzuela, M.[Biopesticide activity from drimanic compounds to control tomato pathogens]Biopesticide activity from drimanic compounds to control tomato pathogens

Eugenol (4-allyl-2-methoxyphenol) (1) has been reported to possess antioxidant and anticancer properties. In an attempt to enhance intrinsic activity of this natural compound, some derivatives were synthesized. Eugenol was extracted from cloves oil and further, the eugenol analogues (2-6) were ob...


Carrasco, H.Espinoza, L.Cardile, V.Gallardo, C.Cardona, W.Lombardo, L.Catálan, K.Cuellar, M.Russo, A.[Eugenol and its Synthetic Analogues Inhibit Cell Growth of Human Cancer Cells (Part I)]Eugenol and its Synthetic Analogues Inhibit Cell Growth of Human Cancer Cells (Part I)

The beta(3) adrenergic receptor is raising as an important drug target for the treatment of pathologies such as diabetes, obesity, depression, and cardiac diseases among others. Several attempts to obtain selective and high affinity ligands have been made. Currently, Mirabegron is the only availa...


Apablaza, G.Montoya, L.Morales-Verdejo, C.Mellado, M.Cuellar, M.Lagos, C.F.Soto-Delgado, J.Chung, H.Pessoa-Mahana, C.D.Mella, J.[2D-QSAR and 3D-QSAR/CoMSIA studies on a series of (R)-2-((2-(1H-Indol-2-yl)ethyl)amino)-1-phenylethan-1-ol with human β3-adrenergic activity]2D-QSAR and 3D-QSAR/CoMSIA studies on a series of (R)-2-((2-(1H-Indol-2-yl)ethyl)amino)-1-phenylethan-1-ol with human β3-adrenergic activity

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