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To map the genetic sources of trypanotolerance in mice, a linkage analysis of survival following trypanosome challenge was performed by selective genotyping in a large F2 population produced by crossing the resistant C57BL/6 and susceptible BALB/c inbred mouse lines. We report evidence of a chrom...


Kemp, Stephen J.Darvasi, A.Soller, M.Teale, A.J.[Genetic control of resistance to trypanosomiasis]Genetic control of resistance to trypanosomiasis

Tsetse fly-transmitted trypanosomes (Trypanosoma spp.) cause 'sleeping sickness' in man and have a serious impact on livestock-based agriculture in large areas of Africa. Multigene control of variation in susceptibility to trypanosomiasis is known to occur in mice, where the C57BI/6 (B6) strain i...


Kemp, Stephen J.Iraqi, F.A.Darvasi, A.Soller, M.Teale, A.J.[Localisation of genes controlling resistance to trypanosomiasis in mice]Localisation of genes controlling resistance to trypanosomiasis in mice

Tsetse fly-transmitted trypanosomes (Trypanosoma spp.) cause 'sleeping sickness' in man and have a serious impact on livestock-based agriculture in large areas of Africa. Multigene control of variation in susceptibility to trypanosomiasis is known to occur in mice, where the C57BI/6 (B6) strain i...


Kemp, Stephen J.Iraqi, F.A.Darvasi, A.Soller, M.Teale, A.J.[Localization of genes controlling resistance to trypanosomiasis in mice]Localization of genes controlling resistance to trypanosomiasis in mice

The goal of the Complex Trait Consortium is to promote the development of resources that can be used to understand, treat and ultimately prevent pervasive human diseases. Existing and proposed mouse resources that are optimized to study the actions of isolated genetic loci on a fixed background a...


Churchill, G.A.Airey, D.C.Allayee, H.Angel, J.M.Attie, A.D.Beatty, J.Beavis, W.D.Belknap, J.K.Bennett, B.Berrettini, W.Bleich, A.Bogue, M.Broman, K.W.Buck, K.J.Buckler, E.Burmeister, M.Chesler, E.J.Cheverud, J.M.Clapcote, S.Cook, M.N.Cox, R.D.Crabbe, J.C.Crusio, W.E.Darvasi, A.Deschepper, C.F.Doerge, R.W.Farber, C.R.Forejt, J.Gaile, D.Garlow, S.J.Geiger, H.Gershenfeld, H.Gordon, T.Gu, J.Gu, W.Haan, G. deHayes, N.L.Heller, C.Himmelbauer, H.Hitzemann, R.Hunter, K.Hsu, H.-C.Iraqi, F.A.Ivandic, B.Jacob, H.J.Jansen, R.C.Jepsen, K.J.Johnson, D.K.Johnson, T.E.Kempermann, G.Kendziorski, C.Kotb, M.Kooy, R.F.Llamas, B.Lammert, F.Lassalle, J.M.Lowenstein, P.R.Lu, L.Lusis, A.Manly, K.F.Marcucio, R.Matthews, D.Medrano, J.F.Miller, D.R.Mittleman, G.Mock, B.A.Mogil, J.S.Montagutelli, X.Morahan, G.Morris, D.G.Mott, R.Nadeau, J.H.Nagase, H.Nowakowski, R.S.O'Hara B.F.Osadchuk, A.V.Page, G.P.Paigen, B.Paigen, K.Palmer, A.A.Pan, H.J.Peltonen-Palotie, L.Peirce, J.Pomp, D.Pravenec, M.Prows, D.R.Qi, Z.Reeves, R.H.Roder, J.Rosen, G.D.Schadt, E.E.Schalkwyk, L.C.Seltzer, Z.Shimomura, K.Shou, S.Sillanpaa, M.J.Siracusa, L.D.Snoeck, H.W.Spearow, J.L.Svenson, K.Tarantino, L.M.Threadgill, D.Toth, L.A.Valdar, W.Pardo-Manuel de Villena, F.Warden, C.Whatley, S.Williams, R.W.Wiltshire, T.Yi, N.Zhang, D.Zhang, M.Zou, F.[The Collaborative Cross, a community resource for the genetic analysis of complex traits]The Collaborative Cross, a community resource for the genetic analysis of complex traits

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