Background
Rhipicephalus appendiculatus is the primary vector of Theileria parva, the etiological agent of East Coast fever (ECF), a devastating disease of cattle in sub-Saharan Africa. We hypothesized that a vaccine targeting tick proteins that are involved in attachment and feeding might affect...
Olds, Cassandra L.
,
Mwaura, S.
,
Odongo, David O.
,
Scoles, Glen A.
,
Bishop, R.
,
Daubenberger, C.A.
,
[Induction of humoral immune response to multiple recombinant Rhipicephalus appendiculatus antigens and their effect on tick feeding success and pathogen transmission]
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Induction of humoral immune response to multiple recombinant Rhipicephalus appendiculatus antigens and their effect on tick feeding success and pathogen transmission
There are no commercially available vaccines against human protozoan parasitic diseases, despite the success of vaccination-induced long-term protection against infectious diseases. East Coast fever, caused by the protist Theileria parva, kills one million cattle each year in sub-Saharan Africa, ...
Norling, M.
,
Bishop, Richard P.
,
Pelle, Roger
,
Weihong Qi
,
Henson, S.
,
Drábek, E.F.
,
Tretina, K.
,
Odongo, D.
,
Mwaura, S.
,
Njoroge, T.
,
Bongcam-Rudloff, E.
,
Daubenberger, C.A.
,
Silva, J.C.
,
[The genomes of three stocks comprising the most widely utilized live sporozoite Theileria parva vaccine exhibit very different degrees and patterns of sequence divergence]
,
The genomes of three stocks comprising the most widely utilized live sporozoite Theileria parva vaccine exhibit very different degrees and patterns of sequence divergence
T cells bearing the gamma-delta antigen can constitute up to 50% of T cells in peripheral blood and lymphoid organs of calves below six months of age. This observation prompted us to investigate the involvement of gamma-delta T cells in the immune response of yound calves against Theileria parva.
Camels are the most valuable livestock species in the Horn of Africa and play a pivotal role in the nutritional sustainability for millions of people. Their health status is therefore of utmost importance for the people living in this region. Streptococcus agalactiae, a Group B Streptococcus (GBS...
Fischer, A.
,
Liljander, Anne M.
,
Kaspar, H.
,
Muriuki, C.
,
Fuxelius, H.H.
,
Bongcam-Rudloff, E.
,
Villiers, Etienne P. de
,
Huber, C.A.
,
Frey, J.
,
Daubenberger, C.A.
,
Bishop, Richard P.
,
Younan, M.
,
Jores, Joerg
,
[Camel Streptococcus agalactiae populations are associated with specific disease complexes and acquired the tetracycline resistance gene tetM via a Tn916-like element]
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Camel Streptococcus agalactiae populations are associated with specific disease complexes and acquired the tetracycline resistance gene tetM via a Tn916-like element
The tick population of Africa includes several important genera belonging to the family Ixodidae. Many of these ticks are vectors of protozoan and rickettsial pathogens including Theileria parva that causes East Coast fever, a debilitating cattle disease endemic to eastern, central and southern A...
Rothen, J.
,
Githaka, Naftaly W.
,
Kanduma, E.G.
,
Olds, Cassandra L.
,
Pflueger, V.
,
Mwaura, S.
,
Bishop, Richard P.
,
Daubenberger, C.A.
,
[Matrix-assisted laser desorption/ionization time of flight mass spectrometry for comprehensive indexing of East African Ixodid tick species]
,
Matrix-assisted laser desorption/ionization time of flight mass spectrometry for comprehensive indexing of East African Ixodid tick species
Background
Theileria parva is a tick-borne protozoan parasite, which causes East Coast Fever, a disease of cattle in sub-Saharan Africa. Like Plasmodium falciparum, the parasite undergoes a transient diploid life-cycle stage in the gut of the arthropod vector, which involves an obligate sexual cy...
Henson, S.
,
Bishop, Richard P.
,
Morzaria, S.P.
,
Spooner, P.R.
,
Pelle, Roger
,
Poveda, L.
,
Ebeling, M.
,
Kung, E.
,
Certa, U.
,
Daubenberger, C.A.
,
Weihong Qi
,
[High-resolution genotyping and mapping of recombination and gene conversion in the protozoan Theileria parva using whole genome sequencing]
,
High-resolution genotyping and mapping of recombination and gene conversion in the protozoan Theileria parva using whole genome sequencing
Liljander, Anne M.
,
Fischer, A.
,
Kaspar, H.
,
Muriuki, C.
,
Fuxelius, H.H.
,
Bongcam-Rudloff, E.
,
Villiers, Etienne P. de
,
Huber, C.A.
,
Frey, J.
,
Daubenberger, C.A.
,
Bishop, Richard P.
,
Younan, M.
,
Jores, Joerg
,
[Biosciences Nairobi-Spread of tetracycline resistance gene tetM via TN916-like elements in East African camel GBS]
,
Biosciences Nairobi-Spread of tetracycline resistance gene tetM via TN916-like elements in East African camel GBS