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A flow cytometric method using anti-parasite antibodies was developed to measure binding of theileria parva sporozoites to the target bovine lymphocyte membrane. Parasite-host cell interactions could be inhibited by monoclonal antibodies to bovine MHC class I and partially by one of two antibodie...


Syfrig, J.Wells, C.Daubenberger, C.A.Musoke, A.J.Naessens, Jan[Proteolytic cleavage of surface proteins enhances susceptibility of lymphocytes to invasion by Theileria parva sporozoites]Proteolytic cleavage of surface proteins enhances susceptibility of lymphocytes to invasion by Theileria parva sporozoites

Camels are the most valuable livestock species in the Horn of Africa and play a pivotal role in the nutritional sustainability for millions of people. Their health status is therefore of utmost importance for the people living in this region. Streptococcus agalactiae, a Group B Streptococcus (GBS...


Fischer, A.Liljander, Anne M.Kaspar, H.Muriuki, C.Fuxelius, H.H.Bongcam-Rudloff, E.Villiers, Etienne P. deHuber, C.A.Frey, J.Daubenberger, C.A.Bishop, Richard P.Younan, M.Jores, Joerg[Camel Streptococcus agalactiae populations are associated with specific disease complexes and acquired the tetracycline resistance gene tetM via a Tn916-like element]Camel Streptococcus agalactiae populations are associated with specific disease complexes and acquired the tetracycline resistance gene tetM via a Tn916-like element
Silva, Joana C.Drabek, E.Harris, D.Orvis, J.Tretina, KyleGotia, T.Bishop, Richard P.Daubenberger, C.A.[Genome-wide genetic variation: 2014 Brief review]Genome-wide genetic variation: 2014 Brief review

The tick population of Africa includes several important genera belonging to the family Ixodidae. Many of these ticks are vectors of protozoan and rickettsial pathogens including Theileria parva that causes East Coast fever, a debilitating cattle disease endemic to eastern, central and southern A...


Rothen, J.Githaka, Naftaly W.Kanduma, E.G.Olds, Cassandra L.Pflueger, V.Mwaura, S.Bishop, Richard P.Daubenberger, C.A.[Matrix-assisted laser desorption/ionization time of flight mass spectrometry for comprehensive indexing of East African Ixodid tick species]Matrix-assisted laser desorption/ionization time of flight mass spectrometry for comprehensive indexing of East African Ixodid tick species

Commercial vaccines based on the tick gut protein Bm86 have been successful in controlling the one-host tick Rhipicephalus (Boophilus) microplus and provide heterologous protection against certain other non-target ixodid tick species. This cross protection, however, does not extend to the three-h...


Olds, Cassandra L.Mwaura, S.Crowder, D.Odongo, D.Oers, M.M. vanOwen, J.Bishop, Richard P.Daubenberger, C.A.[Immunization of cattle with Ra86 impedes Rhipicephalus appendiculatus nymphal-to-adult molting]Immunization of cattle with Ra86 impedes Rhipicephalus appendiculatus nymphal-to-adult molting

Background Theileria parva is a tick-borne protozoan parasite, which causes East Coast Fever, a disease of cattle in sub-Saharan Africa. Like Plasmodium falciparum, the parasite undergoes a transient diploid life-cycle stage in the gut of the arthropod vector, which involves an obligate sexual cy...


Henson, S.Bishop, Richard P.Morzaria, S.P.Spooner, P.R.Pelle, RogerPoveda, L.Ebeling, M.Kung, E.Certa, U.Daubenberger, C.A.Weihong Qi[High-resolution genotyping and mapping of recombination and gene conversion in the protozoan Theileria parva using whole genome sequencing]High-resolution genotyping and mapping of recombination and gene conversion in the protozoan Theileria parva using whole genome sequencing

Liljander, Anne M.Fischer, A.Kaspar, H.Muriuki, C.Fuxelius, H.H.Bongcam-Rudloff, E.Villiers, Etienne P. deHuber, C.A.Frey, J.Daubenberger, C.A.Bishop, Richard P.Younan, M.Jores, Joerg[Biosciences Nairobi-Spread of tetracycline resistance gene tetM via TN916-like elements in East African camel GBS]Biosciences Nairobi-Spread of tetracycline resistance gene tetM via TN916-like elements in East African camel GBS

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