T cells bearing the gamma delta antigen receptor (gamma delta T cells) can constitute up to 50 percent of T cells in the peripheral blood and lymphoid organs of young cattle. We present data showing that gamma delta T cells are involved in immune responses against Theileria parva. Gamma delta T c...
Daubenberger, C.A.
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Taracha, E.L.N.
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Gaidulis, L.
,
Davis, W.C.
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McKeever, Declan J.
,
[Bovine gamma delta T cell responses to the intracellular protozoan parasite Theileria parva]
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Bovine gamma delta T cell responses to the intracellular protozoan parasite Theileria parva
We describe the characterization of two subsets of bovine gamma delta T cells having distinct cell surface phenotype and tissue distribution. One population expresses the previously described 215000 MW WC1 antigen and is negative for the cell-surface differentiation antigens CD2. CD4, and CD8. Th...
MacHugh, Niall D.
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Mburu, J.K.
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Carol, M.J.
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Wyatt, C.R.
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Orden, J.A.
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Davis, W.C.
,
[Identification of two distinct subsets of gamma/delta T cells with unique cell surface phenotype and tissue distribution]
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Identification of two distinct subsets of gamma/delta T cells with unique cell surface phenotype and tissue distribution
The characterisation of a monoclonal antibody (mAb), designated MM1A, which reacts with an antigen molecule on the surface of bovine alfa beta and gama delta TcR+ T cells is described. The mAb immunoprecipitated a series of polypeptides of 21 kDa, 22 kDa, 36 kDa and 44 kDa which is consistent wit...
MacHugh, Niall D.
,
Mburu, J.K.
,
Hamilton, M.J.
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Davis, W.C.
,
[Characterisation of a monoclonal antibody recognising the CD3 epsilon chain of the bovine T cell receptor complex]
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Characterisation of a monoclonal antibody recognising the CD3 epsilon chain of the bovine T cell receptor complex
Davis, W.C.
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MacHugh, Niall D.
,
Park, Y.H.
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Hamilton, M.J.
,
Wyatt, C.R.
,
[Identification of a monoclonal antibody reactive with the bovine orthologue of CD3 (BoCD3)]
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Identification of a monoclonal antibody reactive with the bovine orthologue of CD3 (BoCD3)