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The 'Muguga cocktail' which is composed of three Theileria parva stocks Muguga. Kiambu 5 and Serengeti-transformed has been used extensively for live vaccination against East Coast fever in cattle in eastern, central and southern Africa. Herein we describe the molecular characterization of the T....


Bishop, Richard P.Geysen, D.Spooner, P.R.Skilton, Robert A.Nene, VishvanathDolan, T.T.Morzaria, S.P.[Molecular and immunological characterisation of Theileria parva stocks which are components of the Muguga cocktail used for vaccination against East Coast fever in cattle]Molecular and immunological characterisation of Theileria parva stocks which are components of the Muguga cocktail used for vaccination against East Coast fever in cattle

The effects of holding temperature, pH and medium on the infectivity of Theileria parva sporozoites were investigated using an in vitro infectivity assay. The sporozoite infectivity lasted for 72 h at a holding temperature of 4 C but for only 24 h at 24 degrees C. Sporozoite infectivity was fo...


Kimbita, E.N.Silayo, R.S.Dolan, T.T.[Theileria parva: In vitro studies on the effects of holding temperature, PH and medium on sporozoite infectivity]Theileria parva: In vitro studies on the effects of holding temperature, PH and medium on sporozoite infectivity

Theileria parva (Boleni) stock from Zimbabwe was used to immunise 24 susceptible Friesian calves by infection and treatment with oxytetracycline. Twenty-eight days after immunisation the animals in groups of 6 plus 2 susceptible controls were subjected to challenge: 3 groups with heterologous sto...


Hove, T.Musisi, F.L.Kanhai, G.K.Latif, A.Masaka, S.Munatswa, F.C.Pegram, R.G.Kamwendo, S.P.Quiroga, J.C.Mwangondwe, R.Dolan, T.T.[Challenge of Theileria parva (Boleni) immunised cattle with selected East African Theileria stocks]Challenge of Theileria parva (Boleni) immunised cattle with selected East African Theileria stocks

Over 500 cattle of all age groups on 2 farms in Zimbabwe were immunised against theileriosis using the "infection and treatment" method and disease prevalence and their productivity assessed during a period of 18 months. The immunising stock, Theileria parva (Boleni) was isolated in Zimbabwe. Non...


Pegram, R.G.James, A.D.Bamhare, C.Dolan, T.T.Hove, T.Kanhai, G.K.Latif, A.A.[Effects of immunisation against Theileria parva on beef cattle productivity and economics of control options]Effects of immunisation against Theileria parva on beef cattle productivity and economics of control options
Brown, W.C.Shaw, M.K.Conrad, P.A.Dolan, T.T.[Theileria-parva: Reappearance of schizonts in infected lymphoblastoid cells treated with parvaquone is dependent on interleukin 2-like growth factors]Theileria-parva: Reappearance of schizonts in infected lymphoblastoid cells treated with parvaquone is dependent on interleukin 2-like growth factors

A large database on the transmission of a stabilate of the Theileria parva Muguga stock from one breed of cattle using two stocks of Rhipicephalus appendiculatus, Muguga and O1 Pejeta was developed and analysed. Factors associated with the ticks and cattle, and the infections developing in cattle...


Young, A.S.Dolan, T.T.Morzaria, S.P.Mwakima, F.N.Norval, R.A.I.Scott, J.Sherriff, A.Gettinby, G.[Factors influencing infections in Rhipicephalus appendiculatus ticks fed on cattle infected with Theileria parva]Factors influencing infections in Rhipicephalus appendiculatus ticks fed on cattle infected with Theileria parva
Young, A.S.Grootenhuis, J.G.Smith, K.Flowers, M.J.Dolan, T.T.Brocklesby, D.W.[Structures associated with Theileria parasites in eland erythrocytes]Structures associated with Theileria parasites in eland erythrocytes
Dolan, T.T.Injairu, R.Gisemba, F.Maina, J.N.Mbadi, G.Mbwiria, S.K.Mulela, G.H.M.Othieno, D.A.O.[A clinical trial of buparvaquone in the treatment of East Coast fever]A clinical trial of buparvaquone in the treatment of East Coast fever

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