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Haplotype resolution of human genomes is essential to describe and interpret genetic variation and its impact on biology and disease. Our approach to haplotyping relies on converting genomic DNA into a fosmid library, which represents the entire diploid genome as a collection of haploid DNA clone...


Suk, Eun-KyungSchulz, SabrinaMentrup, BirgitHuebsch, ThomasDuitama, JorgeHoehe, Margret R.[A Fosmid pool-based next generation sequencing approach to haplotype-resolve whole genomes]A Fosmid pool-based next generation sequencing approach to haplotype-resolve whole genomes

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