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Eisler, M.C.Arowolo, R.O.A.Gault, E.A.Moloo, S.K.Holmes, P.H.Peregrine, A.S.[Isometamidium concentrations in the sera of Boran cattle. Correlation with prophylaxis against tsetse-transmitted Trypanosoma congolense]Isometamidium concentrations in the sera of Boran cattle. Correlation with prophylaxis against tsetse-transmitted Trypanosoma congolense

Cattle from 50 farms in Mukono County, Uganda, were monitored for trypanosomes every second month over an 18-month period (1995–1996) by mini-anion exchange chromatography and haematocrit centrifugation techniques. Eighteen trypanosome isolates collected from cattle during this period were charac...


Olila, D.McDermott, John J.Eisler, M.C.Mitema, E.S.Patzelt, R.J.Clausen, P.H.Poetzsch, C.J.Zessin, K.H.Mehlitz, D.Peregrine, A.S.[Drug sensitivity of trypanosome populations from cattle in a peri-urban dairy production system in Uganda]Drug sensitivity of trypanosome populations from cattle in a peri-urban dairy production system in Uganda
Machila, N.Fèvre, Eric M.Maudlin, I.Eisler, M.C.[Farmer estimation of live bodyweight of cattle: Implications for veterinary drug dosing in East Africa]Farmer estimation of live bodyweight of cattle: Implications for veterinary drug dosing in East Africa

Sensitivity and specificity of the FAO/IAEA kits for diagnosis of bovine trypanosomosis were investigated using sera from experimental cattle infected by tsetse challenge with cloned populations of Trypanosoma congolense (three populations) or T. vivax (one population). The kits are based on mono...


Eisler, M.C.Lessard, P.Masake, R.A.Moloo, S.K.Peregrine, A.S.[Sensitivity and specificity of antigen-capture ELISAs for diagnosis of Trypanosoma congolense and Trypansoma vivax infections in cattle]Sensitivity and specificity of antigen-capture ELISAs for diagnosis of Trypanosoma congolense and Trypansoma vivax infections in cattle

A survey to investigate resistance to drugs used in the treatment of bovine trypanosomosis was conducted in the eastern province of Zambia between 1996 and 1998. A cross-sectional study was conducted in three districts (Petauke, Katete, Lundazi) at 34 village sampling sites selected at random fr...


Sinyangwe, L.Delespaux, V.Brandt, J.Geerts, S.Mubanga, J.Machila, N.Holmes, P.H.Eisler, M.C.[Trypanocidal drug resistance in eastern province of Zambia]Trypanocidal drug resistance in eastern province of Zambia

The relationship between serum concentrations of the prophylactic trypanocidal drug isometamidium chloride and protection against tsetse challenge with two populations of Trypanosoma congolense was investigated in Boran (Bos indicus) cattle, using an isometamidium-ELISA. Isometamidium chloride (S...


Eisler, M.C.Gault, E.A.Moloo, S.K.Holmes, P.H.Peregrine, A.S.[Concentrations of isometamidium in the sera of cattle challenged with drug-resistant Trypanosoma congolense]Concentrations of isometamidium in the sera of cattle challenged with drug-resistant Trypanosoma congolense

A study using a structured questionnaire was conducted in Busia District, Western Kenya and Kwale District, Coastal Kenya to obtain qualitative and quantitative information from 256 cattle owners about their production systems, their perceptions of the diseases encountered in their cattle, the ...


Machila, N.Wanyangu, S.W.McDermott, John J.Welburn, S.C.Maudlin, I.Eisler, M.C.[Cattle owners' perceptions of African bovine trypanosomiasis and its control in Busia and Kwale Districts of Kenya]Cattle owners' perceptions of African bovine trypanosomiasis and its control in Busia and Kwale Districts of Kenya

This study assessed the degree of isometamidium resistance of trypanosomes infecting cattle in the upper Didessa valley of western Ethiopia. An initial prevalence study was conducted to identify sites with a high risk of trypanosmosis in cattle. The trypanosome prevalence varied widely, with t...


Tewelde, N.Abebe, G.Eisler, M.C.McDermott, John J.Greiner, M.Afework, Y.Kyule, M.Munstermann, S.Zessin, K.H.Clausen, P.H.[Application of field methods to assess isometamidium resistance of trypanosomes in cattle in western Ethiopia]Application of field methods to assess isometamidium resistance of trypanosomes in cattle in western Ethiopia

Field studies were conducted to assess the occurrence of resistance to isometamidium chloride and diminazene aceturate in trypanosomes infecting cattle in Kenedougou Province of Burkina Faso. Forty-five of the 166 villages in Kenedougou were randomly sampled and visited to assess livestock numb...


McDermott, John J.Woitag, T.Sidibe, I.Bauer, B.Diarra, B.Ouédraogo, D.Kamuanga, M.Peregrine, A.S.Eisler, M.C.Zessin, K.H.[Field studies of drug-resistant cattle trypanosomes in Kenedougou Province, Burkina Faso]Field studies of drug-resistant cattle trypanosomes in Kenedougou Province, Burkina Faso

Control of trypanosomes in cattle, sheep and goats in endemic areas has depended largely on the use of chemotherapeutic or chemoprophylactic agents. One such agent is homidium. The normal use of homidium has been in the treatment of infections due to both Trypanosoma congolense and T.vivax in cat...


Murilla, G.A.Peregrine, A.S.Holmes, P.H.Eisler, M.C.Ndung'u, J.M.[Investigation into the effects of Trypanosoma congolense infections on the pharmacokinetics of Homidium in Boran cattle]Investigation into the effects of Trypanosoma congolense infections on the pharmacokinetics of Homidium in Boran cattle

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