The indirect enzyme-linked immunosorbent assay (ELISA) for the detection of anti-trypanosomal antibodies in bovine serum was adapted for use with dried blood spots on filter paper. Aborbance (450 nm) results for samples were expressed as percent positivity, i.e., percentage of the median absorban...
Hopkins, J.S.
,
Chitambo, H.
,
Machila, N.
,
Luckins, A.G.
,
Rae, P.F.
,
Bossche, P. van den
,
Eisler, M.C.
,
[Adaptation and validation of antibody-ELISA using dried blood spots on filter paper for epidemiological surveys of tsetse-transmitted trypanosomosis in cattle]
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Adaptation and validation of antibody-ELISA using dried blood spots on filter paper for epidemiological surveys of tsetse-transmitted trypanosomosis in cattle
Drug resistant trypanosome infections in livestock have been Reported from 13 sub-Saharan countries so far, in eight of which multiple resistance occurs. Since new trypanocides are unlikely to appear on the market in the near future, information about the occurrence, extent and impact of drug res...
Gall, Y.
,
Woitag, J.
,
Bauer, B.
,
Sidibe, I.
,
McDermott, John J.
,
Eisler, M.C.
,
Mehlitz, D.
,
Clausen, P.H.
,
[Detection of trypanocide failure in cattle: Diagnostic potential of PCR compared to parasitological methods]
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Detection of trypanocide failure in cattle: Diagnostic potential of PCR compared to parasitological methods
Trypanocidal drugs are the most widely applied method of trypanosomosis control in Africa and the only control method in Latin America and Asia . Treatment recommendations and strategies for chemotherapeutic control of trypanosomosis depends on information of trypanosomosis risk and the prevalenc...
Eisler, M.C.
,
McDermott, John J.
,
Mdachi, R.
,
Murilla, G.
,
Sinyangwe, L.
,
Mubanga, J.
,
Machila, N.
,
Mbwambo, H.
,
Coleman, P.G.
,
Clausen, P.H.
,
Bauer, B.
,
Sidibe, I.
,
Geerts, S.
,
Holmes, P.H.
,
Peregrine, A.S.
,
[Rapid method for the assessment of trypanocidal drug resistance in the field]
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Rapid method for the assessment of trypanocidal drug resistance in the field
Bovine trypanosomiasis caused by pathogenic trypanosomes, and cyclically transmitted by tsetse flies, is considered to be a major disease constraint to livestock production in sub-Saharan Africa, preventing full use of the land to feed the rapidly increasing human population. Privatisation of vet...
Machila, N.
,
Eisler, M.C.
,
Wanyangu, S.W.
,
McDermott, John J.
,
Welburn, S.C.
,
Maudlin, I.
,
[Cattle owners' perceptions of African bovine trypanosomiasis and its control in Busia and Kwale districts of Kenya]
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Cattle owners' perceptions of African bovine trypanosomiasis and its control in Busia and Kwale districts of Kenya
To investigate the importance of trypanosomosis, resistance to trypanocidal drugs and the potential impact of integrated control measures on these factors, a 3-phase study was initiated. The first phase was a cross-sectional study in which tsetse apparent density, cattle trypanosome prevalence, t...
McDermott, John J.
,
Sidibe, I.
,
Bauer, B.
,
Diarra, B.
,
Clausen, P.H.
,
Woitay, T.
,
Ouédraogo, T.
,
Kamuanga, M.
,
Peregrine, A.S.
,
Eisler, M.C.
,
Mehlitz, D.
,
[Field studies on the Development and impact of drug resistant animal trypanosomes in market oriented production systems in the Southern Guinean zone of West Africa]
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Field studies on the Development and impact of drug resistant animal trypanosomes in market oriented production systems in the Southern Guinean zone of West Africa
Isometamidium chloride (Samorin, Trypanidium is a phenanthridine-aromatic amidine that is commonly used in cattle as a prophylactic agent against trypanosomiasis. Although the compound has been used for over 30 years, very little is known about its mode of action. Various workers have demonstrate...
Peregrine, A.S.
,
Eisler, M.C.
,
Flynn, J.N.
,
Katende, J.
,
Gault, E.A.
,
Kinabo, L.D.B.
,
Homes, P.H.
,
[Generation of monoclonal antibodies to the anti-trypanosomal drug Samorin]
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Generation of monoclonal antibodies to the anti-trypanosomal drug Samorin
Anderson, N.E.
,
Mubanga, J.
,
Fèvre, Eric M.
,
Picozzi, K.
,
Eisler, M.C.
,
Thomas, R.
,
[Characterisation of the wildlife reservoir community for human and animal trypanosomiasis in the Luangwa Valley, Zambia]
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Characterisation of the wildlife reservoir community for human and animal trypanosomiasis in the Luangwa Valley, Zambia
Welburn, S.C.
,
Coleman, P.G.
,
Maudlin, I.
,
Fèvre, Eric M.
,
Odiit, M.
,
Eisler, M.C.
,
[Crisis, what crisis? Control of Rhodesian sleeping sickness]
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Crisis, what crisis? Control of Rhodesian sleeping sickness