Two groups of five Boran (Bos indicus) cattle were infected with one of two populations of Trypanosoma congolense; one drug-sensitive (IL1180), and one drug-resistant (IL3330). The animals were then treated intramuscularly with homidium bromide at a dose rate of 1.0 mg kg - bodyweight 7 days afte...
Murilla, G.A.
,
Peregrine, A.S.
,
Ndung'u, J.M.
,
Holmes, P.H.
,
Eisler, M.C.
,
[The effects of drug-sensitive and drug-resistant Trypanosoma congolense infections on the pharmacokinetics of homidium in Boran cattle]
,
The effects of drug-sensitive and drug-resistant Trypanosoma congolense infections on the pharmacokinetics of homidium in Boran cattle
Two enzyme-linked immunosorbent assays (ELISA) for the determination of homidium in serum of treated cattle have been developed and evaluated. One is a direct competition (Assay 1) and the other an indirect competition assay (Assay 2). Both assays are highly sensitive with a limit of detection of...
Murilla, G.
,
Eisler, M.C.
,
Peregrine, A.S.
,
Ndung'u, J.M.
,
Holmes, P.H.
,
[Development and evaluation of an enzyme-linked immunosorbent assay (ELISA) for the determination of the trypanocidal drug homidium in serum of treated cattle]
,
Development and evaluation of an enzyme-linked immunosorbent assay (ELISA) for the determination of the trypanocidal drug homidium in serum of treated cattle
Pharmacokinetic studies on the trypanocidal drug homidium bromide using a competitive enzyme immunoassay (detection limit 0.1 ng/mL) are reported for non-infected Friesian and Boran steers following treatment with homidium bromide at a dose of 1.0 mg/kg b.w. Following intravenous (i.v.) treatment...
Murilla, G.
,
Holmes, P.H.
,
Peregrine, A.S.
,
Eisler, M.C.
,
Ndung'u, J.M.
,
[Some pharmacokinetic parameters of the trypanocidal drug homidium bromide in Friesian and Boran steers using an enzyme-linked immunosorbent assay (ELISA)]
,
Some pharmacokinetic parameters of the trypanocidal drug homidium bromide in Friesian and Boran steers using an enzyme-linked immunosorbent assay (ELISA)
A retrospective case–control study of human brucellosis in urban, peri-urban, and rural areas in Kampala, Uganda was undertaken to find the risks associated with the disease using the medical records of Mulago National Referral Hospital (Mulago Hospital). From the Brucella agglutination test (BAT...
Makita, K.
,
Fèvre, Eric M.
,
Waiswa, C.
,
Kaboyo, W.
,
Bronsvoort, B.M. de C.
,
Eisler, M.C.
,
Welburn, S.C.
,
[Human brucellosis in urban and peri-urban areas of Kampala, Uganda]
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Human brucellosis in urban and peri-urban areas of Kampala, Uganda
Classifying, describing and understanding the natural environment is an important element of studies of human, animal and ecosystem health, and baseline ecological data are commonly lacking in remote environments of the world. Human African trypanosomiasis is an important constraint on human well...
Anderson, N.E.
,
Bessell, P.R.
,
Mubanga, J.
,
Thomas, R.
,
Eisler, M.C.
,
Fèvre, Eric M.
,
Welburn, S.C.
,
[Ecological monitoring and health research in Luambe National Park, Zambia: Generation of baseline data layers]
,
Ecological monitoring and health research in Luambe National Park, Zambia: Generation of baseline data layers
Background
A retrospective case-control study was undertaken to examine the spatial risk factors for human brucellosis in Kampala, Uganda.
Methods
Information on age, sex and month of diagnosis was derived from records from plate agglutination tests undertaken at Mulago Hospital, Kampala. Informa...
Makita, K.
,
Fèvre, Eric M.
,
Waiswa, C.
,
Kaboyo, W.
,
Eisler, M.C.
,
Welburn, S.C.
,
[Spatial epidemiology of hospital-diagnosed brucellosis in Kampala, Uganda]
,
Spatial epidemiology of hospital-diagnosed brucellosis in Kampala, Uganda
Anderson, N.E.
,
Mubanga, J.
,
Fèvre, Eric M.
,
Picozzi, K.
,
Eisler, M.C.
,
Thomas, R.
,
[Characterisation of the wildlife reservoir community for human and animal trypanosomiasis in the Luangwa Valley, Zambia]
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Characterisation of the wildlife reservoir community for human and animal trypanosomiasis in the Luangwa Valley, Zambia
Welburn, S.C.
,
Coleman, P.G.
,
Maudlin, I.
,
Fèvre, Eric M.
,
Odiit, M.
,
Eisler, M.C.
,
[Crisis, what crisis? Control of Rhodesian sleeping sickness]
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Crisis, what crisis? Control of Rhodesian sleeping sickness