To formally quantify the level of under-detection of Trypanosoma brucei rhodesiense sleeping sickness (SS) during an epidemic in Uganda, a decision tree (under-detection) model was developed; concurrently, to quantify the subset of undetected cases that sought health care but were not diagnosed, ...
Odiit, M.
,
Coleman, P.G.
,
Liu, W.C.
,
McDermott, John J.
,
Fèvre, Eric M.
,
Welburn, S.C.
,
Woolhouse, Mark E.J.
,
[Quantifying the level of under-detection of Trypanosoma brucei rhodesiense sleeping sickness cases]
,
Quantifying the level of under-detection of Trypanosoma brucei rhodesiense sleeping sickness cases
The tapeworm Taenia solium is the parasite responsible for neurocysticercosis, a neglected tropical disease of public health importance, thought to cause approximately 1/3 of epilepsy cases across endemic regions. The consumption of undercooked infected pork perpetuates the parasite’s life-cycle ...
Thomas, L.F.
,
Glanville, William A. de
,
Cook, Elizabeth A.J.
,
Bronsvoort, B.M. de C.
,
Handel, I.
,
Wamae, C.N.
,
Kariuki, S.
,
Fèvre, Eric M.
,
[Modelling the risk of Taenia solium exposure from pork produced in western Kenya]
,
Modelling the risk of Taenia solium exposure from pork produced in western Kenya
Classifying, describing and understanding the natural environment is an important element of studies of human, animal and ecosystem health, and baseline ecological data are commonly lacking in remote environments of the world. Human African trypanosomiasis is an important constraint on human well...
Anderson, N.E.
,
Bessell, P.R.
,
Mubanga, J.
,
Thomas, R.
,
Eisler, M.C.
,
Fèvre, Eric M.
,
Welburn, S.C.
,
[Ecological monitoring and health research in Luambe National Park, Zambia: Generation of baseline data layers]
,
Ecological monitoring and health research in Luambe National Park, Zambia: Generation of baseline data layers
Background: Q fever in Kenya is poorly reported and its surveillance is highly neglected. Standard empiric
treatment for febrile patients admitted to hospitals is antimalarials or penicillin-based antibiotics, which have no
activity against Coxiella burnetii. This study aimed to assess the seropr...
Njeru, J.
,
Henning, K.
,
Pletz, M.W.
,
Heller, R.
,
Forstner, C.
,
Kariuki, S.
,
Fèvre, Eric M.
,
Neubauer, H.
,
[Febrile patients admitted to remote hospitals in Northeastern Kenya: seroprevalence, risk factors and a clinical prediction tool for Q-Fever]
,
Febrile patients admitted to remote hospitals in Northeastern Kenya: seroprevalence, risk factors and a clinical prediction tool for Q-Fever
Foodborne diseases (FBDs) are a major cause of morbidity and mortality in the human population. Accurate information on the burden of FBDs is needed to inform policy makers and allocate appropriate resources for food safety control and intervention. Consequently, in 2006 the WHO launched an initi...
Torgerson, P.R.
,
Silva, N.R. de
,
Fèvre, Eric M.
,
Kasuga, F.
,
Rokni, M.B.
,
Zhou, X.N.
,
Sripa, B.
,
Gargouri, N.
,
Willingham, A.L.
,
Stein, C.
,
[The global burden of foodborne parasitic diseases: An update]
,
The global burden of foodborne parasitic diseases: An update
Background
Antimicrobial resistance is one of the great challenges facing global health security in the modern era. Wildlife, particularly those that use urban environments, are an important but understudied component of epidemiology of antimicrobial resistance. We investigated antimicrobial resi...
Hassell, J.M.
,
Ward, M.J.
,
Muloi, D.
,
Bettridge, Judy M.
,
Robinson, T.P.
,
Kariuki, S.
,
Ogendo, A.
,
Kiiru, J.
,
Imboma, T.
,
Kang'ethe, Erastus K.
,
Öghren, E.M.
,
Williams, N.J.
,
Begon, M.
,
Woolhouse, Mark E.J.
,
Fèvre, Eric M.
,
[Clinically relevant antimicrobial resistance at the wildlife–livestock–human interface in Nairobi: An epidemiological study]
,
Clinically relevant antimicrobial resistance at the wildlife–livestock–human interface in Nairobi: An epidemiological study
Coxiella burnetii, the causative agent of Query fever (Q fever), is among the most highly infectious zoonotic pathogens transmitted among livestock, with chronic effects challenging to veterinary and medical detection and care systems. Transmission among domestic livestock species can vary region...
Larson, P.S.
,
Espira, L.
,
Grabow, C.
,
Wang, C.A.
,
Muloi, D.
,
Browne, A.S.
,
Deem, S.L.
,
Fèvre, Eric M.
,
Foufopoulos, J.
,
Hardin, R.
,
Eisenberg, J.N.S.
,
[The sero‐epidemiology of Coxiella burnetii (Q fever) across livestock species and herding contexts in Laikipia County, Kenya]
,
The sero‐epidemiology of Coxiella burnetii (Q fever) across livestock species and herding contexts in Laikipia County, Kenya
Land-use change is predicted to act as a driver of zoonotic disease emergence through human exposure to novel microbial diversity, but evidence for the effects of environmental change on microbial communities in vertebrates is lacking. We sample wild birds at 99 wildlife-livestock-human interface...
Hassell, J.M.
,
Ward, M.J.
,
Muloi, D.
,
Bettridge, Judy M.
,
Phan, H.
,
Robinson, T.P.
,
Ogendo, A.
,
Imboma, T.
,
Kiiru, J.
,
Kariuki, S.
,
Begon, M.
,
Kang'ethe, Erastus K.
,
Woolhouse, Mark E.J.
,
Fèvre, Eric M.
,
[Deterministic processes structure bacterial genetic communities across an urban landscape]
,
Deterministic processes structure bacterial genetic communities across an urban landscape
The importance of household socio-economic position (SEP) in shaping individual infectious disease risk is increasingly recognised, particularly in low income settings. However, few studies have measured the extent to which this association is consistent for the range of pathogens that are typica...
Glanville, William A. de
,
Thomas, L.F.
,
Cook, Elizabeth A.J.
,
Bronsvoort, B.M. de C.
,
Wamae, N.C.
,
Kariuki, S.
,
Fèvre, Eric M.
,
[Household socio-economic position and individual infectious disease risk in rural Kenya]
,
Household socio-economic position and individual infectious disease risk in rural Kenya
Background: African swine fever (ASF), caused by African swine fever virus (ASFV), is a severe haemorrhagic disease
of pigs, outbreaks of which can have a devastating impact upon commercial and small-holder pig production. Pig
production in western Kenya is characterised by low-input, free-range ...
Thomas, L.F.
,
Bishop, Richard P.
,
Onzere, Cynthia K.
,
Mcintosh, M.T.
,
Lemire, K.A.
,
Glanville, William A. de
,
Cook, Elizabeth A.J.
,
Fèvre, Eric M.
,
[Evidence for the presence of African swine fever virus in an endemic region of Western Kenya in the absence of any reported outbreak]
,
Evidence for the presence of African swine fever virus in an endemic region of Western Kenya in the absence of any reported outbreak