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Background Leptospirosis is a neglected zoonosis of public health importance transmitted through contact with contaminated soil, water or urine of infected animals. In pigs the disease is characterized by abortion, still births and weak piglets. A cross-sectional study was conducted in May to Jul...


Ngugi, J.N.Fèvre, Eric M.Mgode, G.F.Obonyo, M.Mhamphi, G.G.Otieno, C.A.Cook, Elizabeth A.J.[Seroprevalence and associated risk factors of leptospirosis in slaughter pigs: A neglected public health risk, western Kenya]Seroprevalence and associated risk factors of leptospirosis in slaughter pigs: A neglected public health risk, western Kenya

Background The neglected zoonotic diseases (NZD) are an understudied group that are a major cause of illness throughout the developing world. In general, little is known about the prevalence and burden of NZDs in affected communities, particularly in relation to other infectious diseases with whi...


Fèvre, Eric M.Glanville, William A. deThomas, L.F.Cook, Elizabeth A.J.Kariuki, S.Wamae, C.N.[An integrated study of human and animal infectious disease in the Lake Victoria crescent small-holder crop-livestock production system, Kenya]An integrated study of human and animal infectious disease in the Lake Victoria crescent small-holder crop-livestock production system, Kenya

The Global Burden of Disease Study (GBD) is a landmark initiative that systematically quantifies the prevalence, morbidity, and mortality for hundreds of diseases, injuries, and risk factors of global health importance. For the neglected tropical diseases (NTDs), the GBD 2010 confirmed a high dis...


Herricks, J.R.Hotez, P.J.Wanga, V.Coffeng, L.E.Haagsma, J.A.Basáñez, M.-G.Buckle, G.Budke, C.M.Carabin, H.Fèvre, Eric M.Fürst, T.Halasa, Y.A.King, C.H.Murdoch, M.E.Ramaiah, K.D.Shepard, D.S.Stolk, W.A.Undurraga, E.A.Stanaway, J.D.Naghavi, M.Murray, C.J.L.[The global burden of disease study 2013: What does it mean for the NTDs?]The global burden of disease study 2013: What does it mean for the NTDs?

Rift Valley fever virus (RVFV) is a zoonotic arbovirus affecting livestock and people. This study was conducted in western Kenya where RVFV outbreaks have not previously been reported. The aims were to document the seroprevalence and risk factors for RVFV antibodies in a community-based sample fr...


Cook, Elizabeth A.J.Grossi-Soyster, E.N.Glanville, William A. deThomas, L.F.Kariuki, S.Bronsvoort, B.M. de C.Wamae, C.N.LaBeaud, A.D.Fèvre, Eric M.[The sero-epidemiology of Rift Valley fever in people in the Lake Victoria Basin of western Kenya]The sero-epidemiology of Rift Valley fever in people in the Lake Victoria Basin of western Kenya

Background Inadequate facilities and hygiene at slaughterhouses can result in contamination of meat and occupational hazards to workers. The objectives of this study were to assess current conditions in slaughterhouses in western Kenya and the knowledge, and practices of the slaughterhouse worker...


Cook, Elizabeth A.J.Glanville, William A. deThomas, L.F.Kariuki, S.Bronsvoort, B.M. de C.Fèvre, Eric M.[Working conditions and public health risks in slaughterhouses in western Kenya]Working conditions and public health risks in slaughterhouses in western Kenya

Commercial layer and indigenous chicken farming in Nairobi and associated activities in the egg value chains are a source of livelihood for urban families. A value chain mapping framework was used to describe types of inputs and outputs from chicken farms, challenges faced by producers and their ...


Onono, J.O.Alarcón, PabloKarani, M.Muinde, P.Akoko, James M.Carron, M.Fèvre, Eric M.Häsler, BarbaraRushton, Jonathan[Identification of production challenges and benefits using value chain mapping of egg food systems in Nairobi, Kenya]Identification of production challenges and benefits using value chain mapping of egg food systems in Nairobi, Kenya

There are substantial limitations in our understanding of the distribution of antimicrobial resistance (AMR) in humans and livestock in developing countries. Here, we present the results of an epidemiological study examining patterns of AMR in Escherichia coli isolates circulating in sympatric hu...


Muloi, DishonKiiru, J.Ward, M.J.Hassell, James M.Bettridge, Judy M.Robinson, T.P.Bunnik, B.A.D. vanChase-Topping, M.Robertson, G.Pedersen, A.B.Fèvre, Eric M.Woolhouse, Mark E.J.Kang'ethe, Erastus K.Kariuki, S.[Epidemiology of antimicrobial-resistant Escherichia coli carriage in sympatric humans and livestock in a rapidly urbanizing city]Epidemiology of antimicrobial-resistant Escherichia coli carriage in sympatric humans and livestock in a rapidly urbanizing city

Background Antimicrobial resistance (AMR) driven by antibiotic consumption is a growing global health threat. However, data on antimicrobial consumption patterns in low- and middle-income countries (LMICs) is sparse. Here, we investigate the patterns of antibiotic sales in humans and livestock in...


Muloi, DishonFèvre, Eric M.Bettridge, Judy M.Rono, RobertOng’are, DanielHassell, James M.Karani, Maurice K.Muinde, PatrickBunnik, B. vanStreet, A.Chase-Topping, M.Pedersen, A.B.Ward, M.J.Woolhouse, Mark E.J.[A cross-sectional survey of practices and knowledge among antibiotic retailers in Nairobi, Kenya]A cross-sectional survey of practices and knowledge among antibiotic retailers in Nairobi, Kenya

Large datasets are often not amenable to analysis using traditional single-step approaches. Here, our general objective was to apply imputation techniques, principal component analysis (PCA), elastic net and generalized linear models to a large dataset in a systematic approach to extract the most...


Tremblay, M.Dahm, J.S.Wamae, C.N.Glanville, William A. deFèvre, Eric M.Dopfer, D.[Shrinking a large dataset to identify variables associated with increased risk of Plasmodium falciparum infection in Western Kenya]Shrinking a large dataset to identify variables associated with increased risk of Plasmodium falciparum infection in Western Kenya

The neglected tropical diseases (NTDs) are characterized by their tendency to cluster within groups of people, typically the poorest and most marginalized. Despite this, measures of clustering, such as within-group correlation or between-group heterogeneity, are rarely reported from community-bas...


Glanville, William A. deThomas, Lian F.Cook, Elizabeth A.J.Bronsvoort, B.M. de C.Wardrop, N.Wamae, C.N.Kariuki, S.Fèvre, Eric M.[General contextual effects on neglected tropical disease risk in rural Kenya]General contextual effects on neglected tropical disease risk in rural Kenya

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