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Cassava is infected by numerous geminiviruses in Africa and India that cause devastating losses to poor farmers. We here describe the molecular diversity of seven representative cassava mosaic geminiviruses (CMGs) infecting cassava from multiple locations in Tanzania. We report for the first time...


Ndunguru, J.Legg, J.P.Aveling, T.Thompson, G.Fauquet, Claude M.[Molecular biodiversity of cassava begomoviruses in Tanzania: evolution of cassava geminiviruses in Africa and evidence for East Africa being a center of diversity of cassava geminiviruses]Molecular biodiversity of cassava begomoviruses in Tanzania: evolution of cassava geminiviruses in Africa and evidence for East Africa being a center of diversity of cassava geminiviruses
Thro, Ann MarieBeachy, Roger N.Bonierbale, Merideth W.Fauquet, Claude M.Henry, GuyHenshaw, Graham G.Hughes, Monica A.Kawano, KazuoRaemakers, C.J.J.M.Roca, William M.Sch"pke, C.Taylor, Nigel J.Visser, Richard G.F.[International research on biotechnology of cassava (tapioca, Manihot esculenta Crantz) and its relevance to Southeast Asian economies: a cassava biotechnology network review]International research on biotechnology of cassava (tapioca, Manihot esculenta Crantz) and its relevance to Southeast Asian economies: a cassava biotechnology network review

The impact of cassava transformation technologies for agricultural development in Africa will depend largely on how successfully these capabilities are transferred and adapted to the African environment and local needs. Here we report on the first successful establishment of cassava regeneration ...


Hankoua, B.Taylor, N.Ng, S.Fawole, I.Puonti-Kaerlas, J.Padmanabhan, C.Yadav, J.S.Fauquet, Claude M.Dixon, A.Fondong, V.N.[Production of the first transgenic cassava in Africa via direct shoot organogenesis from friable embryogenic calli and germination of maturing somatic embryos]Production of the first transgenic cassava in Africa via direct shoot organogenesis from friable embryogenic calli and germination of maturing somatic embryos

Cassava mosaic disease (CMD) caused by cassava mosaic geminiviruses (CMGs) (Geminiviridae:Begomovirus) is undoubtedly the most important constraint to the production of cassava in Africa at the outset of the 21st century. Although the disease was recorded for the first time in the latter part of ...


Legg, J.P.Fauquet, Claude M.[Cassava mosaic geminiviruses in Africa]Cassava mosaic geminiviruses in Africa

The genome of cassava common mosaic potexvirus (CsCMV) has been sequenced from cDNA clones and consists of 6376 nucleotides (nt). A 76 nt untranslated region (UTR) at the 5? terminus was followed by ORF1 which potentially encodes a protein of 1449 amino acids (aa). ORFs 2, 3, and 4 were predicted...


Calvert, Lee A.Cuervo Ibáñez, MaritzaOspina, MDFauquet, Claude M.Ramírez, B.C.[Characterization of cassava common mosaic virus and a defective RNA species]Characterization of cassava common mosaic virus and a defective RNA species
Legg, J.P.Attiogbevi Somado, EklouBarker, IanBeach, LarryCeballos, H.Cuéllar, Wilmer J.Elkhoury, WaridGerling, DanHelsen, JanHershey, Clair H.Jarvis, AndyKulakow, P.A.Kumar, LavaLorenzo, JimLynam, John K.McMahon, MatthewMaruthi, GowdaMiano, DougMtunda, KiddoNtawuruhunga, PheneasOkogbenin, EmmanuelPezo, PhembaTerry, Eugene R.Thiele, GrahamThresh, MichaelWadsworth, JonathanWalsh, SteveWinter, StephanTohme, Joseph M.Fauquet, Claude M.[A global alliance declaring war on cassava viruses in Africa]A global alliance declaring war on cassava viruses in Africa

Artificial miRNAs (amiRNA) were generated targeting conserved sequences within the genomes of the two causal agents of Cassava brown streak disease (CBSD): Cassava brown streak virus (CBSV) and Ugandan cassava brown streak virus (UCBSV). Transient expression studies on ten amiRNAs targeting 21 nt...


Wagaba, HenryPatil, Basavaprabhu L.Mukasa, SettumbaAlicai, TitusFauquet, Claude M.Taylor, Nigel J.[Artificial microRNA-derived resistance to Cassava brown streak disease]Artificial microRNA-derived resistance to Cassava brown streak disease

Geminivirus defective interfering DNAs arise spontaneously in mechanically inoculated test plants, and have previously been found with DNA‐B of the bipartite cassava mosaic geminiviruses, but not DNA‐A. Reported here for the first time is the cloning and characterization of a naturally occurring ...


Ndunguru, J.Legg, J.Fofana, B.Aveling, T.Thompson, G.Fauquet, Claude M.[Identification of a defective molecule derived from DNAA of the bipartite begomovirus of East African Cassava Mosaic Virus]Identification of a defective molecule derived from DNAA of the bipartite begomovirus of East African Cassava Mosaic Virus

Cassava brown streak disease (CBSD) threatens food and economic security for smallholder farmers throughout East and Central Africa, and poses a threat to cassava production in West Africa. CBSD is caused by two whitefly-transmitted virus species: Cassava brown streak virus (CBSV) and Ugandan cas...


Beyene, GetuChauhan, Raj DeepikaIlyas, MuhammadWagaba, HenryFauquet, Claude M.Miano, DouglasAlicai, TitusTaylor, Nigel J.[A Virus-derived stacked RNAi construct confers robust resistance to cassava brown streak disease]A Virus-derived stacked RNAi construct confers robust resistance to cassava brown streak disease

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