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The impact of cassava transformation technologies for agricultural development in Africa will depend largely on how successfully these capabilities are transferred and adapted to the African environment and local needs. Here we report on the first successful establishment of cassava regeneration ...


Hankoua, B.Taylor, N.Ng, S.Fawole, I.Puonti-Kaerlas, J.Padmanabhan, C.Yadav, J.S.Fauquet, Claude M.Dixon, A.Fondong, V.N.[Production of the first transgenic cassava in Africa via direct shoot organogenesis from friable embryogenic calli and germination of maturing somatic embryos]Production of the first transgenic cassava in Africa via direct shoot organogenesis from friable embryogenic calli and germination of maturing somatic embryos

Cassava mosaic disease (CMD) caused by cassava mosaic geminiviruses (CMGs) (Geminiviridae:Begomovirus) is undoubtedly the most important constraint to the production of cassava in Africa at the outset of the 21st century. Although the disease was recorded for the first time in the latter part of ...


Legg, J.P.Fauquet, Claude M.[Cassava mosaic geminiviruses in Africa]Cassava mosaic geminiviruses in Africa
Legg, J.P.Attiogbevi Somado, EklouBarker, IanBeach, LarryCeballos, H.Cuéllar, Wilmer J.Elkhoury, WaridGerling, DanHelsen, JanHershey, Clair H.Jarvis, AndyKulakow, P.A.Kumar, LavaLorenzo, JimLynam, John K.McMahon, MatthewMaruthi, GowdaMiano, DougMtunda, KiddoNtawuruhunga, PheneasOkogbenin, EmmanuelPezo, PhembaTerry, Eugene R.Thiele, GrahamThresh, MichaelWadsworth, JonathanWalsh, SteveWinter, StephanTohme, Joseph M.Fauquet, Claude M.[A global alliance declaring war on cassava viruses in Africa]A global alliance declaring war on cassava viruses in Africa

Artificial miRNAs (amiRNA) were generated targeting conserved sequences within the genomes of the two causal agents of Cassava brown streak disease (CBSD): Cassava brown streak virus (CBSV) and Ugandan cassava brown streak virus (UCBSV). Transient expression studies on ten amiRNAs targeting 21 nt...


Wagaba, HenryPatil, Basavaprabhu L.Mukasa, SettumbaAlicai, TitusFauquet, Claude M.Taylor, Nigel J.[Artificial microRNA-derived resistance to Cassava brown streak disease]Artificial microRNA-derived resistance to Cassava brown streak disease

Geminivirus defective interfering DNAs arise spontaneously in mechanically inoculated test plants, and have previously been found with DNA‐B of the bipartite cassava mosaic geminiviruses, but not DNA‐A. Reported here for the first time is the cloning and characterization of a naturally occurring ...


Ndunguru, J.Legg, J.Fofana, B.Aveling, T.Thompson, G.Fauquet, Claude M.[Identification of a defective molecule derived from DNAA of the bipartite begomovirus of East African Cassava Mosaic Virus]Identification of a defective molecule derived from DNAA of the bipartite begomovirus of East African Cassava Mosaic Virus

Cassava brown streak disease (CBSD) threatens food and economic security for smallholder farmers throughout East and Central Africa, and poses a threat to cassava production in West Africa. CBSD is caused by two whitefly-transmitted virus species: Cassava brown streak virus (CBSV) and Ugandan cas...


Beyene, GetuChauhan, Raj DeepikaIlyas, MuhammadWagaba, HenryFauquet, Claude M.Miano, DouglasAlicai, TitusTaylor, Nigel J.[A Virus-derived stacked RNAi construct confers robust resistance to cassava brown streak disease]A Virus-derived stacked RNAi construct confers robust resistance to cassava brown streak disease
Chauhan, Raj DeepikaBeyene, GetuKalyaeva, MarinaFauquet, Claude M.Taylor, Nigel J.[Improvements in Agrobacterium-mediated transformation of cassava (Manihot esculenta Crantz) for large-scale production of transgenic plants]Improvements in Agrobacterium-mediated transformation of cassava (Manihot esculenta Crantz) for large-scale production of transgenic plants
Patil, B.L.Ogwok, E.Wagaba, HenryMohammed, I.U.Yadav, J.S.Bagewadi, B.Taylor, Nigel J.Kreuze, J.F.Maruthi, M.N.Alicai, TitusFauquet, Claude M.[RNAi-mediated resistance to diverse isolates belonging to two virus species involved in Cassava brown streak disease.]RNAi-mediated resistance to diverse isolates belonging to two virus species involved in Cassava brown streak disease.

Cassava brown streak disease (CBSD) has emerged as the most important viral disease of cassava (Manihot esculenta) in Africa and is a major threat to food security. CBSD is caused by two distinct species of ipomoviruses, Cassava brown streak virus and Ugandan cassava brown streak virus, belonging...


Patil, B.L.Legg, J.P.Kanju, E.Fauquet, Claude M.[Cassava brown streak disease: a threat to food security in Africa]Cassava brown streak disease: a threat to food security in Africa

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