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The development of cerebral malaria (CM) in mice with Plasmodium berghei ANKA infection is under genetic control. Brain gene-expression patterns were investigated in well-defined genetically CM-resistant (CM-R; BALB/c and DBA/2) and CM-susceptible (CM-S; C57BL/6 and CBA/J) mice by use of cDNA mic...


Delhaye, N.F.Coltel, N.Puthier, D.Flori, L.Houlgatte, R.Iraqi, F.A.Nguyen, C.Grau, G.E.Rihet, P.[Gene-expression profiling discriminates between cerebral malaria (CM) - susceptible mice and CM-resistant mice]Gene-expression profiling discriminates between cerebral malaria (CM) - susceptible mice and CM-resistant mice

We have previously obtained strong evidence for linkage of mild malaria attack to the MHC region, with a peak close to the tumor necrosis factor (TNF) gene. We screened, for polymorphisms, the entire TNF gene in the same sample of 34 families comprising 197 individuals living in a Plasmodium falc...


Flori, L.Delahaye, N.F.Iraqi, F.A.Hernández Valladares, M.Fumoux, F.Rihet, P.[TNF as a malaria candidate gene: Polymorphism-screening and family-based association analysis of mild malaria attack and parasitemia in Burkina Faso]TNF as a malaria candidate gene: Polymorphism-screening and family-based association analysis of mild malaria attack and parasitemia in Burkina Faso

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