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Mice were immunized with either an isometamidium-human serum albumin (HSA) conjugate or an isometamidium-porcine thyroglobulin conjugate (PTG). Thereafter, monoclonal antibodies (MAbs) IL-A 1001, IL-A 1002, IL-A 1003, 5F7.B7, and 5F7.C9 were generated and selected on the basis that they recognize...


Peregrine, A.S.Eisler, M.C.Katende, J.Flynn, J.N.Gault, E.A.Kinabo, L.D.B.Holmes, P.H.[Generation of monoclonal antibodies to the anti-trypanosomal drug isometamidium]Generation of monoclonal antibodies to the anti-trypanosomal drug isometamidium
Sileghem, M.R.Flynn, J.N.[Suppression of interleukin 2 secretion and interleukin 2 receptor expression during tsetse-transmitted trypanosomiasis in cattle]Suppression of interleukin 2 secretion and interleukin 2 receptor expression during tsetse-transmitted trypanosomiasis in cattle
Sileghem, M.R.Flynn, J.N.[Suppression of T-cell responsiveness during tsetse-transmitted trypanosomiasis in cattle]Suppression of T-cell responsiveness during tsetse-transmitted trypanosomiasis in cattle

Isometamidium chloride (Samorin, Trypanidium is a phenanthridine-aromatic amidine that is commonly used in cattle as a prophylactic agent against trypanosomiasis. Although the compound has been used for over 30 years, very little is known about its mode of action. Various workers have demonstrate...


Peregrine, A.S.Eisler, M.C.Flynn, J.N.Katende, J.Gault, E.A.Kinabo, L.D.B.Homes, P.H.[Generation of monoclonal antibodies to the anti-trypanosomal drug Samorin]Generation of monoclonal antibodies to the anti-trypanosomal drug Samorin

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