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Contagious caprine pleuropneumonia (CCPP), caused by Mycoplasma capricolum subsp. capripneumoniae is a severe disease widespread in Africa and Asia. Limited knowledge is available on the pathogenesis of this organism, mainly due to the lack of a robust in vivo challenge model and the means to do ...


Liljander, Anne M.Sacchini, F.Stoffel, M.H.Schieck, Elise G.Stokar-Regenscheit, N.Labroussaa, F.Heller, M.Salt, J.Frey, J.Falquet, L.Goovaerts, D.Jores, Joerg[Reproduction of contagious caprine pleuropneumonia reveals the ability of convalescent sera to reduce hydrogen peroxide production in vitro]Reproduction of contagious caprine pleuropneumonia reveals the ability of convalescent sera to reduce hydrogen peroxide production in vitro

Contagious caprine pleuropneumonia (CCPP) caused by Mycoplasma capricolum subsp. capripneumoniae is a severe epidemic affecting mainly domestic Caprinae species but also affects wild Caprinae species. M. capricolum subsp. capripneumoniae belongs to the “Mycoplasma mycoides cluster.” The disease f...


Falquet, LaurentLiljander, Anne M.Schieck, Elise G.Gluecks, Ilona V.Frey, J.Jores, Joerg[Complete genome sequences of virulent Mycoplasma capricolum subsp. capripneumoniae strains F38 and ILRI181]Complete genome sequences of virulent Mycoplasma capricolum subsp. capripneumoniae strains F38 and ILRI181

Mycoplasma mycoides subsp. capri (Mmc) and subsp. mycoides (Mmm) are important ruminant pathogens worldwide causing diseases such as pleuropneumonia, mastitis and septicaemia. They express galactofuranose residues on their surface, but their role in pathogenesis has not yet been determined. The M...


Schieck, Elise G.Lartigue, C.Frey, J.Vozza, N.Hegermann, J.Miller, R.A.Valguarnera, E.Muriuki, C.Meens, J.Nene, VishvanathNaessens, JanWeber, J.Lowary, T.L.Vashee, S.Feldman, M.F.Jores, Joerg[Galactofuranose in Mycoplasma mycoides is important for membrane integrity and conceals adhesins but does not contribute to serum resistance]Galactofuranose in Mycoplasma mycoides is important for membrane integrity and conceals adhesins but does not contribute to serum resistance

Contagious caprine pleuropneumonia (CCPP) is a highly contagious disease caused by Mycoplasma capricolum subsp. capripneumoniae that affects goats in Africa and Asia. Current available methods for the diagnosis of Mycoplasma infection, including cultivation, serological assays, and PCR, are time-...


Liljander, Anne M.Mingyan YuO'Brien, E.Heller, M.Nepper, J.F.Weibel, D.B.Gluecks, Ilona V.Younan, M.Frey, J.Falquet, LaurentJores, Joerg[Field-applicable recombinase polymerase amplification assay for rapid detection of Mycoplasma capricolum subsp. Capripneumonia]Field-applicable recombinase polymerase amplification assay for rapid detection of Mycoplasma capricolum subsp. Capripneumonia
Nicholson, P.Fathi, M.A.Fischer, A.Mohan, C.Schieck, Elise G.Mishra, N.Heinimann, A.Frey, J.Wieland, BarbaraJores, Joerg[Detection of Tilapia Lake Virus in Egyptian fish farms experiencing high mortalities in 2015]Detection of Tilapia Lake Virus in Egyptian fish farms experiencing high mortalities in 2015

Camels are the most valuable livestock species in the Horn of Africa and play a pivotal role in the nutritional sustainability for millions of people. Their health status is therefore of utmost importance for the people living in this region. Streptococcus agalactiae, a Group B Streptococcus (GBS...


Fischer, A.Liljander, Anne M.Kaspar, H.Muriuki, C.Fuxelius, H.H.Bongcam-Rudloff, E.Villiers, Etienne P. deHuber, C.A.Frey, J.Daubenberger, C.A.Bishop, Richard P.Younan, M.Jores, Joerg[Camel Streptococcus agalactiae populations are associated with specific disease complexes and acquired the tetracycline resistance gene tetM via a Tn916-like element]Camel Streptococcus agalactiae populations are associated with specific disease complexes and acquired the tetracycline resistance gene tetM via a Tn916-like element

The membrane-associated enzyme l-α-glycerol-3-phosphate oxidase (GlpO) of Mycoplasma mycoides subs. mycoides (Mmm), the causal agent of contagious bovine pleuropneumonia (CBPP) has been identified as a virulence factor responsible for the release of toxic by-products such as H2O2 that mediate hos...


Mulongo, M.M.Frey, J.Smith, K.Schnier, C.Wesonga, H.O.Naessens, JanMcKeever, Declan J.[Cattle immunized against the pathogenic l-α-glycerol-3-phosphate oxidase of Mycoplasma mycoides subs. mycoides in cattle fail to generate neutralizing antibodies and succumb to disease on challenge]Cattle immunized against the pathogenic l-α-glycerol-3-phosphate oxidase of Mycoplasma mycoides subs. mycoides in cattle fail to generate neutralizing antibodies and succumb to disease on challenge

Contagious bovine pleuropneumonia (CBPP) is a serious respiratory disease of cattle caused by Mycoplasma mycoides subsp. mycoides. Current vaccines against CBPP induce short-lived immunity and can cause severe postvaccine reactions. Previous studies have identified the N terminus of the transmemb...


Mulongo, M.Frey, J.Smith, K.Schnier, C.Wesonga, H.O.Naessens, JanMcKeever, Declan J.[Vaccination of cattle with the N terminus of LppQ of Mycoplasma mycoides subsp. mycoides results in type III immune complex disease upon experimental infection]Vaccination of cattle with the N terminus of LppQ of Mycoplasma mycoides subsp. mycoides results in type III immune complex disease upon experimental infection

Background: Mycoplasma mycoides subsp. mycoides (Mmm) is the causative agent of contagious bovine pleuropneumonia (CBPP), a respiratory disease of cattle, whereas the closely related Mycoplasma mycoides subsp. capri (Mmc) is a goat pathogen. Cyto-adherence is a crucial step in host colonization b...


Aye, R.Mwirigi, M.K.Frey, J.Pilo, P.Jores, JoergNaessens, Jan[Cyto-adherence of Mycoplasma mycoides subsp. mycoides to bovine lung epithelial cells]Cyto-adherence of Mycoplasma mycoides subsp. mycoides to bovine lung epithelial cells

Liljander, Anne M.Fischer, A.Kaspar, H.Muriuki, C.Fuxelius, H.H.Bongcam-Rudloff, E.Villiers, Etienne P. deHuber, C.A.Frey, J.Daubenberger, C.A.Bishop, Richard P.Younan, M.Jores, Joerg[Biosciences Nairobi-Spread of tetracycline resistance gene tetM via TN916-like elements in East African camel GBS]Biosciences Nairobi-Spread of tetracycline resistance gene tetM via TN916-like elements in East African camel GBS

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