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Infection of livestock with African trypanosomes leads to haematological changes such as anaemia and pancytopenia and to immune defects, including suppression of T-cell responsiveness and an excessive increase in the CD5+ B-cell population in blood and spleen. It has been shown that certain breed...


Mertens, B.Gaidulis, L.Mwangi, S.Suliman, H.Taylor, K.A.[Development of bovine-specific cytokine reagents at ILRAD]Development of bovine-specific cytokine reagents at ILRAD

This paper determines whether tumour necrosis factor (TNF alpha) (a cytokine that is predominantly secreted by cells of the monocyte/macrophage lineage) production is induced during bovine trypanosomiasis and wheather or not production is correlated with disease. TNF alpha titres in plasma from B...


Sileghem, M.R.Gaidulis, L.[Production of tumour necrosis factor alpha during bovine trypanosomiasis: possible correlation with severity of anaemia associated with the disease]Production of tumour necrosis factor alpha during bovine trypanosomiasis: possible correlation with severity of anaemia associated with the disease

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