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Article

Autor: Tapia, Oscar Riquelme, Ismael Leal, Pamela Sandoval, Alejandra Aedo, Susana Weber, Helga Letelier, Pablo Bellolio, Enrique Villaseca, Miguel Garcia, Patricia Carlos Roa, Juan

Signaling pathway alterations are important in the development of gastric cancer (GC). Deregulation of the PI3K/AKT/mTOR pathway plays a crucial role in the regulation of multiple cellular functions including cell growth, proliferation, metabolism, and angiogenesis. Our goal was to assess express...

Enlace original: http://repositoriodigital.uct.cl/handle/10925/3536

Repositorio Digital Universidad Católica de Temuco
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Tapia, Oscar ,  Riquelme, Ismael ,  Leal, Pamela ,  Sandoval, Alejandra ,  Aedo, Susana ,  Weber, Helga ,  Letelier, Pablo ,  Bellolio, Enrique ,  Villaseca, Miguel ,  Garcia, Patricia ,  Carlos Roa, Juan ,  [The PI3K/AKT/mTOR pathway is activated in gastric cancer with potential prognostic and predictive significance] ,  The PI3K/AKT/mTOR pathway is activated in gastric cancer with potential prognostic and predictive significance
Article

Autor: Ili, Carmen G. Brebi, Priscilla Garcia, Patricia Leal, Pamela Lopez, Jaime Tapia, Oscar Letelier, Pablo Weber, Helga Castillo, Jonathan Roa, Juan C.

Overexpression of Short and Raji variants of Cellular FLICE-like inhibitory protein (c-FLIP) is capable of inhibiting apoptosis, while the function of the Long isoform depends of c-FLIPL concentration in cells. The aim of this study was to determine the effects of c-FLIPL knockdown in cervical ce...

Enlace original: http://repositoriodigital.uct.cl/handle/10925/3558

Repositorio Digital Universidad Católica de Temuco
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Ili, Carmen G. ,  Brebi, Priscilla ,  Garcia, Patricia ,  Leal, Pamela ,  Lopez, Jaime ,  Tapia, Oscar ,  Letelier, Pablo ,  Weber, Helga ,  Castillo, Jonathan ,  Roa, Juan C. ,  [Effects of c-FLIPL Knockdown in Cervical Uterine Carcinoma Cell Lines] ,  Effects of c-FLIPL Knockdown in Cervical Uterine Carcinoma Cell Lines
Article

Autor: Letelier, Pablo Garcia, Patricia Leal, Pamela Alvarez, Hector Ili, Carmen Lopez, Jaime Castillo, Jonathan Brebi, Priscilla Roa, Juan Carlos

The development of miRNA-based therapeutics represents a new strategy in cancer treatment. The objectives of this study were to evaluate the differential expression of microRNAs in gallbladder cancer (GBC) and to assess the functional role of miR-1 and miR-145 in GBC cell behavior. A profile of m...

Enlace original: http://repositoriodigital.uct.cl/handle/10925/3858

Repositorio Digital Universidad Católica de Temuco
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Letelier, Pablo ,  Garcia, Patricia ,  Leal, Pamela ,  Alvarez, Hector ,  Ili, Carmen ,  Lopez, Jaime ,  Castillo, Jonathan ,  Brebi, Priscilla ,  Roa, Juan Carlos ,  [miR-1 and miR-145 act as tumor suppressor microRNAs in gallbladder cancer] ,  miR-1 and miR-145 act as tumor suppressor microRNAs in gallbladder cancer
Article

Autor: Espinoza, Jaime A. Riquelme, Ismael Sagredo, Eduardo A. Rosa, Lorena Garcia, Patricia Bizama, Carolina Apud Bell, Maria Leal, Pamela Weber, Helga Benavente Muñoz, Felipe Vargas, Sergio Romero, Diego Kalergis, Alexis M. Carlos Roa, Juan

Aims Gallbladder cancer (GBC) is an aggressive tumour that is usually diagnosed at advanced stages and is characterised by a poor prognosis. Using public data of normal human tissues, we found that mRNA and protein levels of mucin 5B (MUC5B) and carbonic anhydrase 9 (CA9) were highly increased in...

Enlace original: http://repositoriodigital.uct.cl/handle/10925/3993

Repositorio Digital Universidad Católica de Temuco
Enlace permanente
Espinoza, Jaime A. ,  Riquelme, Ismael ,  Sagredo, Eduardo A. ,  Rosa, Lorena ,  Garcia, Patricia ,  Bizama, Carolina ,  Apud Bell, Maria ,  Leal, Pamela ,  Weber, Helga ,  Benavente Muñoz, Felipe ,  Vargas, Sergio ,  Romero, Diego ,  Kalergis, Alexis M. ,  Carlos Roa, Juan ,  [Mucin 5B, carbonic anhydrase 9 and claudin 18 are potential theranostic markers of gallbladder carcinoma] ,  Mucin 5B, carbonic anhydrase 9 and claudin 18 are potential theranostic markers of gallbladder carcinoma

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