Isometamidium chloride has remained a very important prophylactic and therapeutic drug against trypanosomosis in cattle since its introduction into the market in the 1950s with, unfortunately, a concomitant development of resistance in trypanosomosis endemic areas. Amplified Fragment Length Polym...
Delespaux, V.
,
Geysen, D.
,
Majiwa, P.A.O.
,
Geerts, S.
,
[Identification of a genetic marker for isometamidium chloride resistance in Trypanosoma congolense]
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Identification of a genetic marker for isometamidium chloride resistance in Trypanosoma congolense
A survey to investigate resistance to drugs used in the treatment of bovine trypanosomosis was conducted in the eastern province of Zambia between 1996 and 1998. A cross-sectional study was conducted in three districts (Petauke, Katete, Lundazi) at 34 village sampling sites selected at random fr...
Sinyangwe, L.
,
Delespaux, V.
,
Brandt, J.
,
Geerts, S.
,
Mubanga, J.
,
Machila, N.
,
Holmes, P.H.
,
Eisler, M.C.
,
[Trypanocidal drug resistance in eastern province of Zambia]
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Trypanocidal drug resistance in eastern province of Zambia
Surveys were carried out in the slaughterhouses of Abuko and Banjul and on 16 farms involving 391 cattle in the Central River Division of The Gambia. Using conventional meat inspection, 12 (0.75%) out of 1595 slaughter cattle were found infected with cysticerci of Taenia saginata. On-farm screeni...
Resistance to the drugs used to control African animal trypanosomosis is increasingly recognised as a constraint to livestock production in sub-Saharan Africa. The most commonly used tests for detection of trypanocidal drug resistance are tests using mice or ruminants, but these suffer from lack ...
Eisler, M.C.
,
Brandt, J.
,
Bauer, B.
,
Clausen, P.H.
,
Delespaux, V.
,
Holmes, P.H.
,
Ilemobade, A.
,
Machila, N.
,
Mbwambo, H.
,
McDermott, John J.
,
Mehlitz, D.
,
Murilla, G.
,
Ndung'u, J.M.
,
Peregrine, A.S.
,
Sidibe, I.
,
Sinyangwe, L.
,
Geerts, S.
,
[Standardised tests in mice and cattle for the detection of drug resistance in tsetse-transmitted trypanosomes of African domestic cattle]
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Standardised tests in mice and cattle for the detection of drug resistance in tsetse-transmitted trypanosomes of African domestic cattle
In order to compare the prophylactic effect provided by a poly(D,L-lactide) sustained-release device (SRD) containing isometamidium (ISMM; Trypamidium) with that provided by the classical im injection of the drug, a field trial was carried out at the Madina Diassa Ranch in Mali, beginning in Nove...
Diarra, B.
,
Diall, O.
,
Geerts, S.
,
Kageruka, P.
,
Lemmouchi, Y.
,
Schacht, E.
,
Eisler, M.C.
,
Holmes, P.
,
[Field evaluation of the prophylactic effect of an isometamidium sustained-release device against trypanosomiasis in cattle]
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Field evaluation of the prophylactic effect of an isometamidium sustained-release device against trypanosomiasis in cattle