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A survey to investigate resistance to drugs used in the treatment of bovine trypanosomosis was conducted in the eastern province of Zambia between 1996 and 1998. A cross-sectional study was conducted in three districts (Petauke, Katete, Lundazi) at 34 village sampling sites selected at random fr...


Sinyangwe, L.Delespaux, V.Brandt, J.Geerts, S.Mubanga, J.Machila, N.Holmes, P.H.Eisler, M.C.[Trypanocidal drug resistance in eastern province of Zambia]Trypanocidal drug resistance in eastern province of Zambia

Resistance to the drugs used to control African animal trypanosomosis is increasingly recognised as a constraint to livestock production in sub-Saharan Africa. The most commonly used tests for detection of trypanocidal drug resistance are tests using mice or ruminants, but these suffer from lack ...


Eisler, M.C.Brandt, J.Bauer, B.Clausen, P.H.Delespaux, V.Holmes, P.H.Ilemobade, A.Machila, N.Mbwambo, H.McDermott, John J.Mehlitz, D.Murilla, G.Ndung'u, J.M.Peregrine, A.S.Sidibe, I.Sinyangwe, L.Geerts, S.[Standardised tests in mice and cattle for the detection of drug resistance in tsetse-transmitted trypanosomes of African domestic cattle]Standardised tests in mice and cattle for the detection of drug resistance in tsetse-transmitted trypanosomes of African domestic cattle

In order to compare the prophylactic effect provided by a poly(D,L-lactide) sustained-release device (SRD) containing isometamidium (ISMM; Trypamidium) with that provided by the classical im injection of the drug, a field trial was carried out at the Madina Diassa Ranch in Mali, beginning in Nove...


Diarra, B.Diall, O.Geerts, S.Kageruka, P.Lemmouchi, Y.Schacht, E.Eisler, M.C.Holmes, P.[Field evaluation of the prophylactic effect of an isometamidium sustained-release device against trypanosomiasis in cattle]Field evaluation of the prophylactic effect of an isometamidium sustained-release device against trypanosomiasis in cattle

Trypanocidal drugs are the most widely applied method of trypanosomosis control in Africa and the only control method in Latin America and Asia . Treatment recommendations and strategies for chemotherapeutic control of trypanosomosis depends on information of trypanosomosis risk and the prevalenc...


Eisler, M.C.McDermott, John J.Mdachi, R.Murilla, G.Sinyangwe, L.Mubanga, J.Machila, N.Mbwambo, H.Coleman, P.G.Clausen, P.H.Bauer, B.Sidibe, I.Geerts, S.Holmes, P.H.Peregrine, A.S.[Rapid method for the assessment of trypanocidal drug resistance in the field]Rapid method for the assessment of trypanocidal drug resistance in the field

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