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Journal Article 2003

Autor: Behnke, J.M. Iraqi, F.A. Menge, D. Baker, R.L. Gibson, John P. Wakelin, D.

The host-protective immune response to infection with gastrointestinal (GI) nematodes involves a range of interacting processes that begin with recognition of the parasite's antigens and culminate in an inflammatory reaction in the intestinal mucosa. Precisely which immune effectors are responsib...

Enlace original: https://cgspace.cgiar.org/handle/10568/33007

Investigación en Agricultura
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Behnke, J.M. ,  Iraqi, F.A. ,  Menge, D. ,  Baker, R.L. ,  Gibson, John P. ,  Wakelin, D. ,  [Chasing the genes that control resistance to gastrointestinal nematodes] ,  Chasing the genes that control resistance to gastrointestinal nematodes
Journal Article 2010-02-15

Autor: Behnke, J.M. Menge, D.M. Nagda, S.M. Noyes, H. Iraqi, F.A. Kemp, Stephen J. Mugambi, R.J.M. Baker, R.L. Wakelin, D. Gibson, John P.

A comparison of F2 and F6/7 inter-cross lines of mice, derived from CBA and SWR parental strains, has provided strong evidence for several previously undetected quantitative trait loci (QTL) for resistance to Heligmosomoides bakeri. Five QTL affecting average faecal egg counts and/or worm burdens...

Enlace original: https://cgspace.cgiar.org/handle/10568/358

Investigación en Agricultura
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Behnke, J.M. ,  Menge, D.M. ,  Nagda, S.M. ,  Noyes, H. ,  Iraqi, F.A. ,  Kemp, Stephen J. ,  Mugambi, R.J.M. ,  Baker, R.L. ,  Wakelin, D. ,  Gibson, John P. ,  [Quantitative trait loci for resistance to Heligmosomoides bakeri and associated immunological and pathological traits in mice: comparison of loci on chromosomes 5, 8 and 11 in F2 and F6/7 inter-cross lines of mice] ,  Quantitative trait loci for resistance to Heligmosomoides bakeri and associated immunological and pathological traits in mice: comparison of loci on chromosomes 5, 8 and 11 in F2 and F6/7 inter-cross lines of mice
Journal Article 2006-06-15

Autor: Behnke, J.M. Iraqi, F.A. Mugambi, J.M.M. Clifford, S. Nagda, S.M. Wakelin, D. Kemp, Stephen J. Leyden, B. Gibson, John P.

Fine mapping of quantitative trait loci (QTL) associated with resistance to the gastrointestinal parasite Heligmosomoides polygyrus was achieved on F6/F7 offspring (1076 mice) from resistant (SWR) and susceptible (CBA) mouse strains by selective genotyping (top and bottom 20% selected on total wo...

Enlace original: https://cgspace.cgiar.org/handle/10568/1577

Investigación en Agricultura
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Behnke, J.M. ,  Iraqi, F.A. ,  Mugambi, J.M.M. ,  Clifford, S. ,  Nagda, S.M. ,  Wakelin, D. ,  Kemp, Stephen J. ,  Leyden, B. ,  Gibson, John P. ,  [High resolution mapping of chromosomal regions controlling resistance to gastrointestinal nematode infections in an advanced intercross line of mice] ,  High resolution mapping of chromosomal regions controlling resistance to gastrointestinal nematode infections in an advanced intercross line of mice
Journal Article 2002

Autor: Stella, A. Janson, G.B. Boettcher, P.J. Gibson, John P. Lohuis, M.M. Pagnacco, G.

The objective of this study was to evaluate whether the efficacy of marker assisted selection (MAS) could be improved by considering a confidence interval (CI) of QTL position. Specifically, MAS was applied for within-family selection in a stochastic simulation of a closed nucleus herd. The locat...

Enlace original: https://cgspace.cgiar.org/handle/10568/32972

Investigación en Agricultura
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Stella, A. ,  Janson, G.B. ,  Boettcher, P.J. ,  Gibson, John P. ,  Lohuis, M.M. ,  Pagnacco, G. ,  [Accounting for uncertainty in QTL location in marker-assisted pre-selection of young bulls prior to progeny test] ,  Accounting for uncertainty in QTL location in marker-assisted pre-selection of young bulls prior to progeny test
Journal Article 2006

Autor: Behnke, J.M. Mugambi, J.M.M. Clifford, S. Iraqi, F.A. Baker, R.L. Gibson, John P. Wakelin, D.

Since the publication of the mouse genome, attention has focused on the strains that were selected for sequencing. In this paper we report the results of experiments that characterized the response to infection with the murine gastrointestinal nematode Heligmosomoides polygyrus of eight new strai...

Enlace original: https://cgspace.cgiar.org/handle/10568/33090

Investigación en Agricultura
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Behnke, J.M. ,  Mugambi, J.M.M. ,  Clifford, S. ,  Iraqi, F.A. ,  Baker, R.L. ,  Gibson, John P. ,  Wakelin, D. ,  [Genetic variation in resistance to repeated infections with Heligmosomoides polygyrus bakeri, in inbred mouse strains selected for the mouse genome project] ,  Genetic variation in resistance to repeated infections with Heligmosomoides polygyrus bakeri, in inbred mouse strains selected for the mouse genome project
Newsletter 2001

Autor: Gibson, John P.

Over the past few years, research at ILRI and by its partners has identified genomic regions controlling trypanotolerance in cattle and in mice. In mice many of the genes lying within these genomic regions have been identified, leading the way to identification of the genes controlling trypanotol...

Enlace original: https://cgspace.cgiar.org/handle/10568/28678

Investigación en Agricultura
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Gibson, John P. ,  [Towards an understanding of genetic control of trypanotolerance] ,  Towards an understanding of genetic control of trypanotolerance
Journal Article 2010-11-09

Autor: Goodhead, I. Archibald, A.L. Amwayi, P. Brass, A. Gibson, John P. Hall, N. Hughes, Monica A. Limo, M.K.H. Iraqi, F.A. Kemp, Stephen J. Noyes, H.A.

African trypanosomes are protozoan parasites that cause “sleeping sickness” in humans and a similar disease in livestock. Trypanosomes also infect laboratory mice and three major quantitative trait loci (QTL) that regulate survival time after infection with T. congolense have been identified in t...

Enlace original: https://cgspace.cgiar.org/handle/10568/3500

Investigación en Agricultura
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Goodhead, I. ,  Archibald, A.L. ,  Amwayi, P. ,  Brass, A. ,  Gibson, John P. ,  Hall, N. ,  Hughes, Monica A. ,  Limo, M.K.H. ,  Iraqi, F.A. ,  Kemp, Stephen J. ,  Noyes, H.A. ,  [A comprehensive genetic analysis of candidate genes regulating response to Trypanosoma congolense infection in mice] ,  A comprehensive genetic analysis of candidate genes regulating response to Trypanosoma congolense infection in mice
Journal Article 2001

Autor: Pan, Y. Boettcher, P.J. Gibson, John P.

Bayesian segregation analysis using a Gibbs sampling approach was applied to four sets of simulated data and one set of field data to detect evidence of major genes affecting the evaluated trait. The substitution effect of a major gene and its allelic frequency were estimated for each set of data...

Enlace original: https://cgspace.cgiar.org/handle/10568/28892

Investigación en Agricultura
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Pan, Y. ,  Boettcher, P.J. ,  Gibson, John P. ,  [Bayesian segregation analysis of somatic cell scores of ontario Holstein cattle] ,  Bayesian segregation analysis of somatic cell scores of ontario Holstein cattle
Journal Article 2003

Autor: Waaij, E.H. van der Hanotte, Olivier H. Arendonk, Johan A.M. van Kemp, Stephen J. Kennedy, D. Gibson, John P. Teale, A.J.

Some West African Bos taurus cattle breeds such as the N'Dama and a number of West African Shorthorns are resistant to tsetse fly-transmitted trypanosomosis. The trait is termed trypanotolerance, for which changes in packed red cell volume percent (PCV) and growth rate following infection are ge...

Enlace original: https://cgspace.cgiar.org/handle/10568/29175

Investigación en Agricultura
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Waaij, E.H. van der ,  Hanotte, Olivier H. ,  Arendonk, Johan A.M. van ,  Kemp, Stephen J. ,  Kennedy, D. ,  Gibson, John P. ,  Teale, A.J. ,  [Population parameters for traits defining trypanotolerance in an F2 cross of N'Dama and Boran cattle] ,  Population parameters for traits defining trypanotolerance in an F2 cross of N'Dama and Boran cattle
Journal Article 2003

Autor: Iraqi, F.A. Behnke, J.M. Menge, D.M. Lowe, A.M. Teale, A.J. Gibson, John P. Baker, L.R. Wakelin, D.R.

Quantitative trait loci (QTL) associated with resistance to an intestinal worm in a well-defined murine model are described. These have been identified in an F(2) population derived from resistant (SWR) and susceptible (CBA) parental mouse strains infected with the gastro-intestinal nematode par...

Enlace original: https://cgspace.cgiar.org/handle/10568/29203

Investigación en Agricultura
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Iraqi, F.A. ,  Behnke, J.M. ,  Menge, D.M. ,  Lowe, A.M. ,  Teale, A.J. ,  Gibson, John P. ,  Baker, L.R. ,  Wakelin, D.R. ,  [Chromosomal regions controlling resistance to gastro-intestinal nematode infections in mice] ,  Chromosomal regions controlling resistance to gastro-intestinal nematode infections in mice

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