Trypanosoma congolense is a protozoan parasite that causes severe diseases in livestock. Three major quantative trait loci (QTL), Tir1, Tir2, and Tir3, control the survival time of mice after infection with T. congolense. Congenic mice carrying the C57BL/6 resistance alleles on the A/J background...
Rathkolb, B.
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Noyes, H.A.
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Brass, A.
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Dark, P.
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Fuchs, H.
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Gailus-Durner, V.
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Gibson, John P.
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Angelis, M.H. de
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Ogugo, M.
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Iraqi, F.A.
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Kemp, Stephen J.
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Naessens, Jan
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Pope, M.E.
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Wolf, E.
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Agaba, Morris
,
[Clinical chemistry of congenic mice with quantitative trait loci for predicted responses to Trypanosoma congolense infection]
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Clinical chemistry of congenic mice with quantitative trait loci for predicted responses to Trypanosoma congolense infection
This paper reports the results of a genome-wide search for quantitative trait loci (QTL) influencing immunological responses to infection with the gastro-intestinal nematode parasite Heligmosomoides polygyrus in an F2 population created by crossing the resistant SWR and the susceptible CBA inbr...
Menge, D.M.
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Behnke, J.M.
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Lowe, A.
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Gibson, John P.
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Iraqi, F.A.
,
Baker, R.L.
,
Wakelin, D.
,
[Mapping of chromosomal regions influencing immunological responses to gastrointestinal nematode infections in mice]
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Mapping of chromosomal regions influencing immunological responses to gastrointestinal nematode infections in mice
Quantitative trait loci (QTL) associated with resistance to an intestinal worm in a well-defined murine model are described. These have been identified in an F(2) population derived from resistant (SWR) and susceptible (CBA) parental mouse strains infected with the gastro-intestinal nematode par...