Bayesian segregation analysis using a Gibbs sampling approach was applied to four sets of simulated data and one set of field data to detect evidence of major genes affecting the evaluated trait. The substitution effect of a major gene and its allelic frequency were estimated for each set of data...
Pan, Y.
,
Boettcher, P.J.
,
Gibson, John P.
,
[Bayesian segregation analysis of somatic cell scores of ontario Holstein cattle]
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Bayesian segregation analysis of somatic cell scores of ontario Holstein cattle
Some West African Bos taurus cattle breeds such as the N'Dama and a number of West African Shorthorns are resistant to tsetse fly-transmitted trypanosomosis. The trait is termed trypanotolerance, for which changes in packed red cell volume percent (PCV) and growth rate following infection are ge...
Waaij, E.H. van der
,
Hanotte, Olivier H.
,
Arendonk, Johan A.M. van
,
Kemp, Stephen J.
,
Kennedy, D.
,
Gibson, John P.
,
Teale, A.J.
,
[Population parameters for traits defining trypanotolerance in an F2 cross of N'Dama and Boran cattle]
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Population parameters for traits defining trypanotolerance in an F2 cross of N'Dama and Boran cattle
Quantitative trait loci (QTL) associated with resistance to an intestinal worm in a well-defined murine model are described. These have been identified in an F(2) population derived from resistant (SWR) and susceptible (CBA) parental mouse strains infected with the gastro-intestinal nematode par...
We developed an F(11) AIL population from an F(1) cross of A/J (susceptible) and C57BL/6J (resistant) mouse strains. One thousand F(11) mice were challenged with P.c. chabaudi 54X, and 340 mice selected from the phenotypic extremes for susceptibility and resistance were genotyped for microsatel...
Hernández Valladares, M.
,
Naessens, Jan
,
Gibson, John P.
,
Musoke, A.J.
,
Nagda, S.M.
,
Rihet, P.
,
Ole-MoiYoi, O.K.
,
Iraqi, F.A.
,
[Confirmation and dissection of QTL controlling resistance to malaria in mice]
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Confirmation and dissection of QTL controlling resistance to malaria in mice
A genome-wide scan for quantitative trait loci (QTL) affecting gastrointestinal nematode resistance in sheep was completed using a double backcross population derived from Red Maasai and Dorper ewes bred to F1 rams. This design provided an opportunity to map potentially unique genetic variation a...
Silva, M.V.B.
,
Sonstegard, T.S.
,
Hanotte, Olivier H.
,
Mugambi, J.M.M.
,
García, J.F.
,
Nagda, S.M.
,
Gibson, John P.
,
Iraqi, F.A.
,
McClintock, A.E.
,
Kemp, Stephen J.
,
Boettcher, P.J.
,
Malek, M.
,
Tassell, C.P. van
,
Baker, R.L.
,
[Identification of quantitative trait loci affecting resistance to gastrointestinal parasites in a double backcross population of Red Maasai and Dorper sheep]
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Identification of quantitative trait loci affecting resistance to gastrointestinal parasites in a double backcross population of Red Maasai and Dorper sheep
The expression of three putative QTL for upper thermal tolerance (UTT) was examined in two strains of outbred rainbow trout unselected for this trait using simple-sequence repeat (SSR; microsatellite) markers associated with UTT in backcrosses of lines selected on this trait. Two-way diallel lots...
Perry, G.M.L.
,
Danzmann, R.G.
,
Ferguson, M.M.
,
Gibson, John P.
,
[Quantitative trait loci for upper thermal tolerance in outbred strains of rainbow trout (Oncorhynchus mykiss)]
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Quantitative trait loci for upper thermal tolerance in outbred strains of rainbow trout (Oncorhynchus mykiss)
Sons (n = 71 to 75) of each of six Holstein sires were genotyped at 69 microsatellite loci covering a total of 676 cM on chromosomes 3, 5, 9, 10, 13, 15, 17, 20, 23, and 26. Estimates of quantitative trait loci (QTL) effect and location were made using a least squares interval mapping approach ba...
Plante, Y.
,
Gibson, John P.
,
Nadesalingam, J.
,
Mehrabani-Yeganeh, H.
,
Lefebvre, S.
,
Vandervoort, G.
,
Jansen, G.B.
,
[Detection of quantitative trait loci affecting milk production traits on 10 chromosomes in Holstein cattle]
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Detection of quantitative trait loci affecting milk production traits on 10 chromosomes in Holstein cattle
A genome-wide scan was performed to detect quantitative trait loci (QTL) for resistance to the gastrointestinal nematode Haemonchus contortus in a double backcross population of Red Maasai and Dorper sheep. The mapping population comprised six sire families, with 1026 lambs in total. The lambs we...
Marshall, Karen
,
Mugambi, J.M.M.
,
Nagda, S.M.
,
Sonstegard, T.S.
,
Tassell, C.P. van
,
Baker, R.L.
,
Gibson, John P.
,
[Quantitative trait loci for resistance to Haemonchus contortus artificial challenge in Red Maasai and Dorper sheep of East Africa]
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Quantitative trait loci for resistance to Haemonchus contortus artificial challenge in Red Maasai and Dorper sheep of East Africa
Orenge, C.O.
,
Munga, L.
,
Kimwele, C.N.
,
Kemp, Stephen J.
,
Korol, A.
,
Gibson, John P.
,
Hanotte, Olivier H.
,
Soller, M.
,
[Trypanotolerance in N’Dama x Boran crosses under natural trypanosome challenge: Effect of test-year environment, gender, and breed composition]
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Trypanotolerance in N’Dama x Boran crosses under natural trypanosome challenge: Effect of test-year environment, gender, and breed composition